IARC MONOGRAPHS ON THE EVALUATION OF CARCINOGENIC ...

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NAPHTHALENE 435 Worley, G., Erwin, C.W., Goldstein, R.F., Provenzale, J.M. & Ware, E.R. (1996) Delayed development of sensorineural hearing loss after neonatal hyperbilirubinemia: A case report with brain magnetic resonance imaging. Dev. Med. Child Neurol., 38, 271–277 Xu, G., Zigler, J.S., Jr & Lou, M.F. (1992) The possible mechanism of naphthalene cataract in rat and its prevention by an aldose reductase inhibitor (ALØ1576). Exp. Eye Res., 54, 63–72 Yamauchi, T., Komura, S. & Yagi, K. (1986) Serum lipid peroxide levels of albino rats administered naphthalene. Biochem. int., 13, 1–6 Yang, M., Koga, M., Katoh, T. & Kawamoto, T. (1999) A study for the proper application of urinary naphthols, new biomarkers for airborne polycyclic aromatic hydrocarbons. Arch. environ. Contam. Toxicol., 36, 99–108 Yrjänheikki, E., Pyy, L., Hakala, E., Lapinlampi, T., Lisko, A. & Vähäkangas, K. (1995) Exposure to polycyclic aromatic hydrocarbons in a new coking plant. Am. ind. Hyg. Assoc. J., 56, 782–787 Yu, X., Wang, X., Bartha, R. & Rosen, J.D. (1990) Supercritical fluid extraction of coal tar contaminated soil. Environ. Sci. Technol., 24, 1732–1738 Zey, J.N. & Stephenson, R. (1986) Roofing and Waterproofing Sites, Chicago, Illinois (Health Hazard Evaluation Report No. HETA-85-416-1742), Cincinnati, OH, National Institute for Occupational Safety and Health Zinkham, W.H. & Childs, B. (1958) A defect of glutathione metabolism in erythrocytes from patients with a naphthalene-induced hemolytic anemia. Pediatrics, 22, 461–471 Zuelzer, W.W. & Apt, L. (1949) Acute hemolytic anemia due to naphthalene poisoning. A clinical and experimental study. J. Am. med. Assoc., 141, 185–190
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WORLD HEALTH ORGANIZATION INTERNATI
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IARC MONOGRAPHS In 1969, the Intern
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iv IARC MONOGRAPHS VOLUME 82 3.2 Th
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vi IARC MONOGRAPHS VOLUME 82 SOME M
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IARC WORKING GROUP ON THE EVALUATIO
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PARTICIPANTS 5 Observer, representi
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PREAMBLE
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10 IARC MONOGRAPHS VOLUME 82 plasms
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12 IARC MONOGRAPHS VOLUME 82 collec
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14 agents present. For processes, i
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16 IARC MONOGRAPHS VOLUME 82 Finall
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18 IARC MONOGRAPHS VOLUME 82 and mi
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20 IARC MONOGRAPHS VOLUME 82 (c) St
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22 IARC MONOGRAPHS VOLUME 82 may le
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24 IARC MONOGRAPHS VOLUME 82 It is
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26 IARC MONOGRAPHS VOLUME 82 Data r
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28 when there is strong evidence th
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30 IARC MONOGRAPHS VOLUME 82 Vol. 7
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GENERAL REMARKS ON THE SUBSTANCES C
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SOME TRADITIONAL HERBAL MEDICINES
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44 which may include, for example,
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46 2. Use of Traditional Herbal Med
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48 IARC MONOGRAPHS VOLUME 82 decade
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50 IARC MONOGRAPHS VOLUME 82 Table
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52 3.2.1 Definition of herbal medic
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54 3.2.8 Individual supply Herbal m
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58 3.3.2 Germany (see Kraft, 1999;
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60 beyond placebo, and this informa
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62 3.3.5 Canada The Canadian Food a
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64 of adverse reactions to OTC drug
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66 IARC MONOGRAPHS VOLUME 82 3.3.12
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68 IARC MONOGRAPHS VOLUME 82 Jellin
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70 IARC MONOGRAPHS VOLUME 82 Simila
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72 IARC MONOGRAPHS VOLUME 82 Figure
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74 diameter of 4-6 cm or more, lobe
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76 1.2 Use 1.2.1 Aristolochia conto
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78 1.3.3 Aristolochia fangchi Compo
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80 1.6.2 Structural and molecular f
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82 chromatographic separation with
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84 may contain aristolochic acids.
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86 IARC MONOGRAPHS VOLUME 82 A bila
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88 received distilled water. The an
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90 IARC MONOGRAPHS VOLUME 82 Figure
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92 varied from undetectable (< 0.02
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94 lochic acids enhanced immune res
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96 4.4 Genetic and related effects
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Table 3 (contd) Details of study DN
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Table 4. DNA adduct formation with
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Table 4 (contd) Details of study Co
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Table 5 (contd) Species Treatment I
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Table 6. DNA adduct formation by ar
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Table 6 (contd) Test system Assay D
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Table 6 (contd) Test system Assay D
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Table 7. Polymerase action on arist
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Table 8 (contd) Test system Drosoph
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116 of the forestomach and lung of
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118 lochic acid II (three metabolit
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120 IARC MONOGRAPHS VOLUME 82 Che,
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122 IARC MONOGRAPHS VOLUME 82 Healt
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124 IARC MONOGRAPHS VOLUME 82 Nishi
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126 IARC MONOGRAPHS VOLUME 82 Schme
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128 IARC MONOGRAPHS VOLUME 82 Yang,
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130 Figure 1. Morinda officinalis H
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132 1.3.2 Morinda officinalis A num
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134 by Soxhlet extraction with ethy
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136 2.1 Case-control studies 2.1.1
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138 3. Studies of Cancer in Experim
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140 1,3-Dihydroxy-2-hydroxymethylan
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142 4.3 Reproductive and developmen
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Table 1 (contd) Test system Result
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146 5.1 Exposure data 5. Summary of
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148 IARC MONOGRAPHS VOLUME 82 Brigg
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150 IARC MONOGRAPHS VOLUME 82 Nusko
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D. SENECIO SPECIES AND RIDDELLIINE
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metry (Witte et al., 1992). Thin-la
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sex were killed after a seven-week
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4.2.2 Experimental systems SOME TRA
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Table 1. Genetic and related effect
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Riddelliine induced unscheduled DNA
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5.3 Animal carcinogenicity data In
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SOME TRADITIONAL HERBAL MEDICINES 1
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SOME MYCOTOXINS
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172 Aflatoxin G 1 IARC MONOGRAPHS V
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Table 2 (contd) Method no. Aflatoxi
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178 indicates that A. flavus and A.
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Table 4. Occurrence of aflatoxin B1
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182 IARC MONOGRAPHS VOLUME 82 aflat
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Table 6. Co-occurrence of aflatoxin
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186 IARC MONOGRAPHS VOLUME 82 Figur
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188 1.4 International exposure esti
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190 (c) Impact of establishing maxi
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192 IARC MONOGRAPHS VOLUME 82 used
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Table 10 (contd) Reference Area Uni
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198 were collapsed into a conventio
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Table 11 (contd) Reference Area Stu
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202 IARC MONOGRAPHS VOLUME 82 histo
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204 IARC MONOGRAPHS VOLUME 82 resid
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Table 12. Summary of principal case
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208 IARC MONOGRAPHS VOLUME 82 disea
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210 3. Studies of Cancer in Experim
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212 IARC MONOGRAPHS VOLUME 82 diet
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214 3.4 Administration with known c
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216 IARC MONOGRAPHS VOLUME 82 The 8
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218 observed in rat liver slices, a
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222 IARC MONOGRAPHS VOLUME 82 an α
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224 (mainly hepatocellular carcinom
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226 IARC MONOGRAPHS VOLUME 82 but i
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228 lordosis and reduction in conce
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232 IARC MONOGRAPHS VOLUME 82 sampl
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234 In eight subjects (four from Ho
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Table 16 (contd) Test system Result
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240 IARC MONOGRAPHS VOLUME 82 anima
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242 difference between the two stud
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244 IARC MONOGRAPHS VOLUME 82 HBV-t
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246 In a large cohort study in Shan
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248 experimental data in showing th
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250 IARC MONOGRAPHS VOLUME 82 Ander
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252 IARC MONOGRAPHS VOLUME 82 Buetl
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254 IARC MONOGRAPHS VOLUME 82 Denis
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256 IARC MONOGRAPHS VOLUME 82 Galla
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258 IARC MONOGRAPHS VOLUME 82 Heino
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260 IARC MONOGRAPHS VOLUME 82 Jalon
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262 IARC MONOGRAPHS VOLUME 82 Kirk,
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264 IARC MONOGRAPHS VOLUME 82 Lunn,
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266 IARC MONOGRAPHS VOLUME 82 Olubu
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268 IARC MONOGRAPHS VOLUME 82 Roll,
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270 IARC MONOGRAPHS VOLUME 82 Stett
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272 IARC MONOGRAPHS VOLUME 82 Verge
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274 IARC MONOGRAPHS VOLUME 82 Yang,
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Table 1. IARC evaluations Previous
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278 kernels and in less than 0.1% o
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280 2.5.3 Cottonseed A. flavus is a
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294 IARC MONOGRAPHS VOLUME 82 8. Re
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296 IARC MONOGRAPHS VOLUME 82 Guo,
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298 IARC MONOGRAPHS VOLUME 82 Marti
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300 IARC MONOGRAPHS VOLUME 82 Sharm
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302 (d ) Solubility: Soluble in wat
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304 1.4 Occurrence Fumonisins have
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306 Table 1 (contd) IARC MONOGRAPHS
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308 (c) Formation in commodities ot
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312 IARC MONOGRAPHS VOLUME 82 3.1 O
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314 3.2.2 Rat IARC MONOGRAPHS VOLUM
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316 with NDEA and fumonisin B 1, wh
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318 IARC MONOGRAPHS VOLUME 82 In pi
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Figure 2. Allometric relationship b
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322 IARC MONOGRAPHS VOLUME 82 obser
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324 IARC MONOGRAPHS VOLUME 82 Hepat
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326 4.2.3 Related studies IARC MONO
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328 4.3.2 Experimental systems IARC
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330 and litters on postnatal day 21
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Table 4. Genetic and related effect
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334 IARC MONOGRAPHS VOLUME 82 The f
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336 IARC MONOGRAPHS VOLUME 82 (d )
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338 IARC MONOGRAPHS VOLUME 82 treat
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340 4.5.2 Interference with fatty a
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344 5.2 Human carcinogenicity data
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346 IARC MONOGRAPHS VOLUME 82 Alber
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348 IARC MONOGRAPHS VOLUME 82 Chamb
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350 IARC MONOGRAPHS VOLUME 82 Floss
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352 IARC MONOGRAPHS VOLUME 82 Hiroo
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354 IARC MONOGRAPHS VOLUME 82 Lee,
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356 IARC MONOGRAPHS VOLUME 82 Mobio
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358 IARC MONOGRAPHS VOLUME 82 Prelu
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360 IARC MONOGRAPHS VOLUME 82 Savar
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362 IARC MONOGRAPHS VOLUME 82 Steve
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364 IARC MONOGRAPHS VOLUME 82 Flett
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366 IARC MONOGRAPHS VOLUME 82 Yu, C
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368 disulfide, carbon tetrachloride
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Table 1 (contd) Sample matrix Sampl
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Table 3. Naphthalene production (th
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374 1.4 Occurrence 1.4.1 Natural oc
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Table 5. Occupational exposure to n
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378 water assuming a water concentr
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380 (Scheepers & Bos, 1992). The av
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382 (d ) Biodegradation Studies on
Page 391 and 392: 384 IARC MONOGRAPHS VOLUME 82 Table
Page 393 and 394: 386 3.2 Inhalation exposure 3.2.1 M
Page 395 and 396: 388 3.3.2 Rat Ten BD I and BD III r
Page 397 and 398: Figure 1. Main metabolic pathways o
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Page 403 and 404: 396 IARC MONOGRAPHS VOLUME 82 1-240
Page 405 and 406: 398 IARC MONOGRAPHS VOLUME 82 Perfu
Page 407 and 408: 400 Siegel and Wason (1986) reviewe
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Page 411 and 412: 404 IARC MONOGRAPHS VOLUME 82 to id
Page 413 and 414: 406 IARC MONOGRAPHS VOLUME 82 Alkal
Page 415 and 416: 408 hyperplasia, atrophy, chronic i
Page 417 and 418: 410 had deficient glucose-6-phospha
Page 419 and 420: Table 10. Genetic and related effec
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Page 423 and 424: 416 assay with or without metabolic
Page 425 and 426: 418 There is some evidence of devel
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Page 429 and 430: 422 IARC MONOGRAPHS VOLUME 82 Conkl
Page 431 and 432: 424 IARC MONOGRAPHS VOLUME 82 Envir
Page 433 and 434: 426 IARC MONOGRAPHS VOLUME 82 Ho, C
Page 435 and 436: 428 IARC MONOGRAPHS VOLUME 82 Lynch
Page 437 and 438: 430 IARC MONOGRAPHS VOLUME 82 O’B
Page 439 and 440: 432 IARC MONOGRAPHS VOLUME 82 Schee
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Page 445 and 446: 438 (e) Spectroscopy data: Infrared
Page 447 and 448: 440 Methods of isotope-dilution GC-
Page 449 and 450: 442 IARC MONOGRAPHS VOLUME 82 produ
Page 451 and 452: 444 1.4 Occurrence A comprehensive
Page 453 and 454: 446 IARC MONOGRAPHS VOLUME 82 In a
Page 455 and 456: Table 4. Occupational exposure to s
Page 457 and 458: Table 4 (contd) Country and year of
Page 459 and 460: 452 IARC MONOGRAPHS VOLUME 82 study
Page 461 and 462: 454 Completely insulating personal
Page 463 and 464: 456 (a) Air IARC MONOGRAPHS VOLUME
Page 465 and 466: 458 (see monograph in this volume);
Page 467 and 468: 460 IARC MONOGRAPHS VOLUME 82 The F
Page 469 and 470: 462 IARC MONOGRAPHS VOLUME 82 at th
Page 471 and 472: Table 10. Characteristics of cohort
Page 473 and 474: Table 10 (contd) Reference (country
Page 475 and 476: 468 IARC MONOGRAPHS VOLUME 82 worke
Page 477 and 478: 470 IARC MONOGRAPHS VOLUME 82 cance
Page 479 and 480: 472 IARC MONOGRAPHS VOLUME 82 more
Page 481 and 482: 474 mandelic acid samples were coll
Page 483 and 484: 476 3.1.2 Rat Groups of 50 male and
Page 485 and 486: 478 incidence of lung tumours was s
Page 487 and 488: 480 1968; Engström et al., 1978a,b
Page 489 and 490: 482 IARC MONOGRAPHS VOLUME 82 Many
Page 491 and 492: 484 Haufroid et al. (2001) examined
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486 (c) Metabolism IARC MONOGRAPHS
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488 IARC MONOGRAPHS VOLUME 82 (1.07
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490 IARC MONOGRAPHS VOLUME 82 high
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492 IARC MONOGRAPHS VOLUME 82 accor
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494 IARC MONOGRAPHS VOLUME 82 posit
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496 IARC MONOGRAPHS VOLUME 82 guine
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498 IARC MONOGRAPHS VOLUME 82 pancr
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500 Styrene caused a dose-dependent
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502 On the basis of these results,
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504 4.4 Genetic and related effects
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506 IARC MONOGRAPHS VOLUME 82 repor
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508 (iv) Protein adducts Christakop
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510 showed increased levels of N7-d
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Table 14. Genetic and related effec
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514 increase in the induction of mi
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516 IARC MONOGRAPHS VOLUME 82 The r
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518 Circulating styrene 7,8-oxide m
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520 The increased risks for lymphat
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522 biologically significant extent
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524 IARC MONOGRAPHS VOLUME 82 Berga
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526 IARC MONOGRAPHS VOLUME 82 Chakr
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528 IARC MONOGRAPHS VOLUME 82 Darra
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530 IARC MONOGRAPHS VOLUME 82 Flodi
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532 IARC MONOGRAPHS VOLUME 82 Hansc
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534 IARC MONOGRAPHS VOLUME 82 Karak
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536 IARC MONOGRAPHS VOLUME 82 Latti
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538 IARC MONOGRAPHS VOLUME 82 Mäki
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540 IARC MONOGRAPHS VOLUME 82 Mutti
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542 IARC MONOGRAPHS VOLUME 82 Otten
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544 IARC MONOGRAPHS VOLUME 82 Salom
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546 IARC MONOGRAPHS VOLUME 82 Sulli
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548 IARC MONOGRAPHS VOLUME 82 Vodic
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550 IARC MONOGRAPHS VOLUME 82 pheny
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LIST OF ABBREVIATIONS USED IN THIS
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LIST OF ABBREVIATIONS 555 HPRT: hyp
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CUMULATIVE CROSS INDEX TO IARC MONO
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ortho-Anisidine 27, 63 (1982); Supp
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CUMULATIVE INDEX 561 Beryllium fluo
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CUMULATIVE INDEX 563 Chlorambucil 9
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CUMULATIVE INDEX 565 Clomiphene cit
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CUMULATIVE INDEX 567 Dibenzodioxins
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1,4-Dimethylphenanthrene 32, 349 (1
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Formaldehyde 29, 345 (1982); Suppl.
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Hypochlorite salts 52, 159 (1991) I
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CUMULATIVE INDEX 575 Malondialdehyd
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Methylthiouracil 7, 53 (1974); Supp
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CUMULATIVE INDEX 579 N-Nitrosodieth
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CUMULATIVE INDEX 581 Paracetamol 50
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Pronetalol hydrochloride 13, 227 (1
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CUMULATIVE INDEX 585 Sodium arsenit
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CUMULATIVE INDEX 587 Tetranitrometh
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V Vat Yellow 4 48, 161 (1990) Vinbl
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List of IARC Monographs on the Eval
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Volume 61 Schistosomes, Liver Fluke
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