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how do adolescents define depression? - cIRcle - University of ...

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Chapter II: Literature Review<br />

affect and behavior are largely determined by the way in which he or she structures the world<br />

(Beck et al., 1979).<br />

Pharmacological interventions involve medications such as tricyclic antidepressants<br />

(TCAs), serotonin reuptake inhibitors (SSRIs), and monoamine oxidase inhibitors (MAOIs). The<br />

combination <strong>of</strong> the two therapies, psychotherapy and pharmacotherapy, known as multimodal,<br />

has been found to be the most beneficial for the treatment <strong>of</strong> acute depressive disorders in young<br />

people (AACAP, 1998). Opinions differ regarding the most beneficial order <strong>of</strong> the treatments<br />

and which is the most efficient modality (Jacobson, Dobson, & Truax, 1996). In fact, the<br />

combination <strong>of</strong> the two therapies is sel<strong>do</strong>m studied (AACAP, 1998). In North America, the use<br />

<strong>of</strong> pharmacological therapies has increased over the past decade for both children and<br />

a<strong>do</strong>lescents. There are few studies, <strong>how</strong>ever, <strong>of</strong> the safety and efficacy <strong>of</strong> most <strong>of</strong> the medication<br />

prescribed (Emslie et al., 1997; Kurt & Crowley, 2002). Controversy also exists about possible<br />

serious side effects when antidepressants are used to treat <strong>depression</strong> in a<strong>do</strong>lescents (Garland,<br />

2004a, 2004b).<br />

Treatment <strong>of</strong> a<strong>do</strong>lescent <strong>depression</strong> mostly consists <strong>of</strong> psychotherapy and<br />

pharmacotherapy (Brent et al., 1997; Clarke, Rohde, Lewinsohn, Hops, & Seeley, 1999; Clarke<br />

et al., 2001; Mufson, Weissman, Moreau, & Garfinkel, 1999); <strong>how</strong>ever, there is emerging<br />

evidence that early intervention with at-risk <strong>of</strong>fspring a<strong>do</strong>lescents <strong>of</strong> adults treated for <strong>depression</strong><br />

may prevent <strong>depression</strong> (Clarke et al., 2001). Furthermore, protective factors may even hedge<br />

depressive symptomatology. Studies indicate that influences <strong>of</strong> family and school attachments<br />

can protect a<strong>do</strong>lescents against harmful behaviors associated with mental health problems (Ma &<br />

Zhang, 2002; Resnick et al., 1997). For example, the B.C. government initiated planning and<br />

providing for improved early intervention, working with community organizations and<br />

institutions (e.g., Child and Youth Mental Health Plan for BC; Ministry <strong>of</strong> Children and Family<br />

Development, 2004). In the A<strong>do</strong>lescent Health Survey <strong>of</strong> over 36,000 students in grades 7 to 12<br />

in the US, Resnick, Harris, and Blum (1993) report that the three protective factors for "quietly<br />

disturbed behaviors" (e.g., poor body image, emotional stress, suicidal involvement, p. 4) were<br />

family connectedness, school connectedness, and low family stress.<br />

27

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