Pesticide residues in food — 2007: Toxicological ... - ipcs inchem

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Figure 2. Main pathways of biotransformation of cyhalothrin in mammals
F 3 C
Cl
O
O
C N
O
C H 3
C H 3
Es ter cleavage
F 3 C
Cl
O
O H
H
C N
O
C H 3
C H 3
Compound Ia
Compound III
Cl
H 3
C
+
O
CH 3
O H
H
O
O
F 3 C Compound Ib
Compound IV
F 3
C
Cl
O
O -Gluc
H O
O
O
C H 3
O H
Compound V
Compound XI
H O
O
O
Compound XXIII
Compound Ia (1RS)-cis-3-(Z-2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanoic acid
Compound Ib (1RS)-trans-3-(Z-2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanoic acid
Compound III (RS)-α-cyano-3-phenoxybenzyl alcohol,Mixture of R and S isomers
Compound IV 3-phenoxybenzaldehyde
Compound V 3-phenoxy benzoic acid
Compound XI EZ)-1-(RS)-2-trans-3-cis-3-(2-chloro-3,3,3-trifluoromethylpropenyl)-2-hydroxymethyl-2-methylcyclopropanoic
acid
Compound XXIII 3-(4’-hydroxyphenoxy) benzoic acid
O H
LAMBDA-CYHALOTHRIN 173–200 JMPR 2007