Pesticide residues in food — 2007: Toxicological ... - ipcs inchem

207
Figure 3. Proposed metabolic pathway of difenoconazole in mammals
CI
O
CI
O
N
O N
N
Difenoconazole
CI
O
CI
O
N
N
N
CI
O
OH
CI
O
N
O N
N
CGA 205374
hydroxy-CGA 205375 (metabolite B)
CI
CI
N
N
O
N
OH
CGA 205375 (metabolite C)
CI
OH
CI
N
N
O
N
OH
hydroxy-CGA 205375 (metabolite A)
CI
CI
O
O
HN
N
CGA 71019
CI
CI
N
O
CGA 189138
OH
O
OH
OH
CGA 205374: 1-(2-chloro-4-(4-chloro-phenoxy)-phenyl)-2-(1,2,4-triazol)-1-yl-ethanone;
CGA 205375 (metabolite C): 1-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-2-(1,2,4-triazol)-1-yl-ethanol;
CGA 71019: 1,2,4-triazole.
CGA 189138: 2-chloro-4-(4-chlorophenoxy)-benzoic acid;
From Capps et al. (1990)
DIFENOCONAZOLE 201–272 JMPR 2007