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Pesticide residues in food — 2007: Toxicological ... - ipcs inchem

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WHO Library Catalogu<strong>in</strong>g-<strong>in</strong>-Publication Data<br />

<strong>Pesticide</strong> <strong>residues</strong> <strong>in</strong> <strong>food</strong> : <strong>2007</strong>, toxicological evaluations, sponsored jo<strong>in</strong>tly by FAO and WHO, with the<br />

support of the International Programme on Chemical Safety / Jo<strong>in</strong>t Meet<strong>in</strong>g of the FAO Panel of Experts on<br />

<strong>Pesticide</strong> Residues <strong>in</strong> Food and the Environment and WHO Core Assessment Group, Geneva, Switzerland,<br />

18–27 September <strong>2007</strong>.<br />

(WHO pesticide <strong>residues</strong> series)<br />

1.<strong>Pesticide</strong> <strong>residues</strong> - toxicity. 2.No-observed-adverse-effect level. 3.Food contam<strong>in</strong>ation. I.FAO Panel of Experts<br />

on <strong>Pesticide</strong> Residues <strong>in</strong> Food and Environment. II.WHO Core Assessment Group on <strong>Pesticide</strong> R esidues. III.<br />

<strong>Pesticide</strong> <strong>residues</strong> <strong>in</strong> <strong>food</strong> <strong>2007</strong> : evaluations. Part 2, <strong>Toxicological</strong>.<br />

ISBN 978 92 4 166523 0 (NLM classification: WA 240)<br />

This report conta<strong>in</strong>s the collective views of two <strong>in</strong>ternational groups of experts and does not necessarily represent the d ecisions<br />

nor the stated policy of the Food and Agriculture Organization of the United Nations or the World Health O rganization.<br />

The preparatory work for the toxicological evaluations of pesticide <strong>residues</strong> carried out by the WHO Expert Group on<br />

<strong>Pesticide</strong> Residues for consideration by the FAO/WHO Jo<strong>in</strong>t Meet<strong>in</strong>g on <strong>Pesticide</strong> Residues <strong>in</strong> Food and the Environment<br />

is actively supported by the International Programme on Chemical Safety with<strong>in</strong> the framework of the I nter-Organization<br />

Programme for the Sound Management of Chemicals.<br />

The International Programme on Chemical Safety (IPCS), established <strong>in</strong> 1980, is a jo<strong>in</strong>t venture of the United N ations<br />

Environment Programme (UNEP), the International Labour Organization (ILO), and the World Health Organization (WHO).<br />

The overall objectives of the IPCS are to establish the scientific basis for assess<strong>in</strong>g the risk to human health and the<br />

e nvironment to exposure from chemicals, through <strong>in</strong>ternational peer-review processes as a prerequisite for the promotion<br />

of chemical safety, and to provide technical assistance <strong>in</strong> strengthen<strong>in</strong>g national capacities for the sound m anagement<br />

of chemicals.<br />

The Inter-Organization Programme for the Sound Management of Chemicals (IOMC) was established <strong>in</strong> 1995 by<br />

UNEP, the Food and Agriculture Organization of the United Nations, WHO, the United Nations Industrial Development<br />

Organization, and the Organisation for Economic Co-operation and Development (Participat<strong>in</strong>g Organizations), follow<strong>in</strong>g<br />

recommendations made by the 1992 United Nations Conference on the Environment and Development to strengthen<br />

cooperation and <strong>in</strong>crease coord<strong>in</strong>ation <strong>in</strong> the field of chemical safety. The purpose of the IOMC is to promote c oord<strong>in</strong>ation<br />

of the policies and activities pursued by the Participat<strong>in</strong>g Organizations, jo<strong>in</strong>tly or separately, to achieve the sound<br />

m anagement of chemicals <strong>in</strong> relation to human health and the environment.<br />

© World Health Organization 2009<br />

All rights reserved. Publications of the World Health Organization can be obta<strong>in</strong>ed from WHO Press, World Health Organization,<br />

20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: bookorders@who.<br />

<strong>in</strong>t). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution<br />

– should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: permissions@who.<strong>in</strong>t).<br />

The designations employed and the presentation of the material <strong>in</strong> this publication do not imply the expression of any op<strong>in</strong>ion<br />

whatsoever on the part of the World Health Organization concern<strong>in</strong>g the legal status of any country, territory, city or area or of<br />

its authorities, or concern<strong>in</strong>g the delimitation of its frontiers or boundaries. Dotted l<strong>in</strong>es on maps represent approximate border<br />

l<strong>in</strong>es for which there may not yet be full agreement.<br />

The mention of specific companies or of certa<strong>in</strong> manufacturers’ products does not imply that they are endorsed or recommended<br />

by the World Health Organization <strong>in</strong> preference to others of a similar nature that are not mentioned. Errors and omissions<br />

excepted, the names of proprietary products are dist<strong>in</strong>guished by <strong>in</strong>itial capital letters.<br />

All reasonable precautions have been taken by the World Health Organization to verify the <strong>in</strong>formation conta<strong>in</strong>ed <strong>in</strong> this publication.<br />

However, the published material is be<strong>in</strong>g distributed without warranty of any k<strong>in</strong>d, either expressed or implied. The<br />

responsibility for the <strong>in</strong>terpretation and use of the material lies with the reader. In no event shall the World Health Organization<br />

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This publication conta<strong>in</strong>s the collective views of an <strong>in</strong>ternational group of experts and does not necessarily represent the<br />

d ecisions or the policies of the World Health Organization.<br />

Typeset <strong>in</strong> India<br />

Pr<strong>in</strong>ted <strong>in</strong> Spa<strong>in</strong>

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