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Photonic crystals in biology

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Poster Session, Tuesday, June 15<br />

Theme A1 - B702<br />

Nano TiO 2 Doped Hydroxyapatite Composites<br />

Azade Yelten<br />

1 , Suat Yilmaz 1 *, S. Agathopoulos, 2 and Faik Nuzhet Oktar, 3-4<br />

1 Department of Metallurgical and Materials Eng<strong>in</strong>eer<strong>in</strong>g, Istanbul University, 34320, Avcilar, Istanbul, Turkey<br />

2 Materials Science and Eng<strong>in</strong>eer<strong>in</strong>g Department, Ioann<strong>in</strong>a University, Greece<br />

3 Department of Radiology, School of Health Related Professions , Marmara University, Istanbul, Turkey<br />

4 Nanotechnology and Biomaterials Application and Research Centre, Marmara University, Istanbul 34722, Turkey<br />

Abstract-We predict here that nano-dopants <strong>in</strong> correct amounts could be very useful to prepare hydroxyapatite (HA) composites, which were<br />

not be used at load-barrier conditions. Here show that nano dopants could be effective if correct amounts <strong>in</strong> the HA matrix will used.<br />

The number of treated skeletal deficiencies steadily<br />

<strong>in</strong>creases <strong>in</strong> a global scale. Effective ways for bone<br />

replacements and enhancement of bone formation together<br />

with research directed to f<strong>in</strong>d ideal biomaterials for graft<strong>in</strong>g<br />

purposes, which will feature biocompatibility and production<br />

simplicity and economy, are required. Hydroxyapatite (HA,<br />

Ca 10 (PO 4 ) 6 (OH) 2 ), the ma<strong>in</strong> m<strong>in</strong>eral component of bones and<br />

teeth, is among the lead<strong>in</strong>g biomaterials satisfy<strong>in</strong>g these<br />

requirements. Nevertheless, pure HA features low mechanical<br />

strength and fracture toughness, which limit their use <strong>in</strong> loadbear<strong>in</strong>g<br />

applications [1]. The applications of pure HA are<br />

restricted to non load-bear<strong>in</strong>g implants due to the poor<br />

mechanical properties of HA. Dop<strong>in</strong>g with (biocompatible or<br />

even better bioactive) oxides may result <strong>in</strong> strong HA<br />

composites [2]. There are lots of studies us<strong>in</strong>g various oxides,<br />

whiskers <strong>in</strong> the literature but they are almost noth<strong>in</strong>g about<br />

add<strong>in</strong>g nano-dopants <strong>in</strong>to HA matrix <strong>in</strong> the recent literature.<br />

The aim of this study is to produce stronger HA composites<br />

add<strong>in</strong>g nano-dopands than regular composites.<br />

Calc<strong>in</strong>ed (at 850 °C) HA powder was produced from fresh<br />

bov<strong>in</strong>e femoral bones (BHA). The nano-dopant TiO2 was<br />

obta<strong>in</strong>ed from Sigma Aldrich TiO with

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