Kerala State Drug Formulary.pdf

More documents

Recommendations

Info

ABBREVIATIONS A/E .......................... - adverse effects amp ......................... - ampoule BD/bid/bd ................. - two times daily bw ........................... - body weight C/I ........................... - contraindication Cap .......................... - capsule CNS .......................... - central nervous system D/I ........................... - drug interaction g ............................. - gram GI/GIT ...................... - gastro intestinal tract hs ............................ - at bed time I .............................. - indication IG ............................ - Immunoglobulin IM ........................... - intramuscularly Inj ........................... - injection IV ............................ - intravenously IU ............................ - international units kg ............................ - kilogram L ............................. - litre max .......................... - maximum mcg ......................... - microgram mdi .......................... - metered dose inhalation mg ........................... - milligram min .......................... - minute mL ........................... - milliliter od ........................... - once daily P/A .......................... - preparations available P/C .......................... - precaution q ............................. - every qid/qds ..................... - four times daily SC ........................... - subcutaneously SJS .......................... - Steven Johnson’s Syndrome SLE .......................... - Systemic Lupus Erythematosus sos .......................... - when required SR ........................... - sustained release stat .......................... - immediately tab .......................... - tablet tid/tds ...................... - three times daily xi
CONTENTS PART I GENERAL ADVICE TO PRESCRIBERS ........................................1 Rational approach to therapeutics ........................................ 1 Variation in dose response .................................................. 3 Adherence with drug treatment ........................................... 5 Adverse effects and drug interactions ................................... 8 P – drug concept ............................................................ 11 Prescription writing ........................................................ 12 Sample Prescription ........................................................ 14 Assessing cost effectiveness in clinical Medicine..................... 14 SECTION –1: DRUGS USED IN ANAESTHESIA ............................ 18 General anaesthetics and oxygen ...................................... 18 Local Anaesthetics ......................................................... 22 Preoperative medication and sedation ................................. 27 Muscle relaxants ............................................................ 30 SECTION – 2: ANALGESICS, ANTIPYRETICS, NONSTEROIDAL ANTI-INFLAMMATORY DRUGS(NSAIDS),MEDICINES USED TO TREAT GOUT, DISEASE MODIFYING AGENTS IN RHEUMATOID DISORDERS (DMARDS) ...................................................... 31 Non opioid Non steroidal anti-inflammatory drugs .................... 31 Opioid analgesics ............................................................ 38 Disease modifying agents used in Rheumatoid disorders ............ 42 <strong>Drug</strong>s used in Gout ......................................................... 47 SECTION – 3: ANTICONVULSANTS / ANTIEPILEPTICS .................. 49 SECTION – 4: ANTIINFECTIVE DRUGS .................................... 61 Antimicrobials ................................................................ 61 Antileprotic drugs .......................................................... 83 Antituberculous drugs ..................................................... 83 Antifungal drugs ............................................................. 83 Antiviral drugs ............................................................... 85 xii
Page 2 and 3: KERALA STATE DRUG FORMULARY NUMBER
Page 4 and 5: CENTRAL DRUG FORMULARY COMMITTEE CH
Page 6 and 7: LIST OF CONTRIBUTORS 1. Dr. K.V. Kr
Page 8 and 9: FOREWORD Medicines play a crucial r
Page 10 and 11: Dr. V. Geetha, Director of Medical
Page 14 and 15: Antiretroviral drugs ..............
Page 16 and 17: Dyes used in ophthalmology ........
Page 18 and 19: Antipsychotic drugs ...............
Page 20 and 21: Eclampsia .........................
Page 23 and 24: PART - I GENERAL ADVICE TO PRESCRIB
Page 25 and 26: General advice to Prescribers Monit
Page 27 and 28: General advice to Prescribers Pharm
Page 29 and 30: General advice to Prescribers refil
Page 31 and 32: General advice to Prescribers neces
Page 33 and 34: General advice to Prescribers 2C19
Page 35 and 36: General advice to Prescribers possi
Page 37 and 38: General advice to Prescribers Cost
Page 39 and 40: General advice to Prescribers Did w
Page 41 and 42: Inhalational agents I:, C/I:,D/I: s
Page 43 and 44: Intravenous General Anaesthetics Re
Page 45 and 46: Local Anaesthetics anaesthesia. Low
Page 47 and 48: Local Anaesthetics A/E: P/A: Dose:
Page 49 and 50: Preoperative Medication PREOPERATIV
Page 51 and 52: Preoperative Medication A/E: P/A: D
Page 53 and 54: SECTION - 2 ANALGESICS, ANTIPYRETIC
Page 55 and 56: Non-Steroidal Anti-Inflammatory Dru
Page 61 and 62: Opioid Analgesics P/A : Injection:
Page 63 and 64:
Opioid Analgesics pain, 100 mg init
Page 65 and 66:
Drugs in Rheumatoid Disorders P/A:
Page 67 and 68:
Drugs in Rheumatoid Disorders IMPOR
Page 69 and 70:
Medicines used for Gout Dose: Admin
Page 71 and 72:
SECTION - 3 ANTI CONVULSANTS/ANTIEP
Page 73 and 74:
Antiepileptics A/E: Cardiovascular
Page 75 and 76:
Antiepileptics Ethosuximide I: Drug
Page 77 and 78:
Antiepileptics hypotonia, coordinat
Page 79 and 80:
Antiepileptics Topiramate I: Adjunc
Page 81 and 82:
Antiepileptics Felbamate I: Unrespo
Page 83 and 84:
SECTION - 4 ANTIINFECTIVE DRUGS ANT
Page 85 and 86:
Pencillins Phenoxymethyl penicillin
Page 87 and 88:
Cephalosporins Cephazolin I: Surgic
Page 89 and 90:
Pencillins Cefdinir I: Pneumonia, c
Page 91 and 92:
Aminoglycosides Gentamicin I: Urina
Page 93 and 94:
Broad spectrum antibiotics I: Ricke
Page 95 and 96:
Macrolides pertussis, endemic trach
Page 97 and 98:
Macrolides photosensitivity; hepati
Page 99 and 100:
Teicoplanin Cost: Tab 50 mg (10) Rs
Page 101 and 102:
Fluoroquinolones A/E: Nausea, epiga
Page 103 and 104:
Sulphonamides A/E: same as in cipro
Page 105 and 106:
Antifungal drugs Sulphacetamide I:
Page 107 and 108:
Antiviral drugs ANTI VIRAL DRUGS An
Page 109 and 110:
Non selective antiviral drugs Dose:
Page 111 and 112:
Antiretroviral drugs Dose: Oral, 30
Page 113 and 114:
Antiretroviral drugs A/E : Rash inc
Page 115 and 116:
Antimalarial drugs Artesunate I: Ml
Page 117 and 118:
Antimalarial drugs Quinine I: Acts
Page 119 and 120:
Antiamoebic and other protozoal dru
Page 121 and 122:
Anthelmintics drugs Other drugs use
Page 123 and 124:
Antifilarial drugs SCHISTOSOMICIDES
Page 125 and 126:
SECTION - 5 ANTIMIGRAINE MEDICINES
Page 127 and 128:
SECTION 6 ANTINEOPLASTIC DRUGS ALKY
Page 129 and 130:
Antimetabolites Cost : Inj: 1 g via
Page 131 and 132:
Antineoplastic Drugs Cost : 5-Fluor
Page 133 and 134:
Cytotoxis Antibiotics P/A: Injectio
Page 135 and 136:
Mitotic Inhibitors Epirubicin I: Ca
Page 137 and 138:
Hormones and Hormonal antagonists P
Page 139 and 140:
Targeted agents Progestins Medroxy
Page 141 and 142:
Cytoprotective agents A/E: Infusion
Page 143 and 144:
Dopaminergic agonist P/A: Dose: Bro
Page 145 and 146:
MAO B Inhibitor MAO B Inhibitor Sel
Page 147 and 148:
Central Anticholinergics daily (wit
Page 149 and 150:
SECTION - 8 DRUGS ACTING ON BLOOD A
Page 151 and 152:
Drug affecting Coagulation P/C: Can
Page 153 and 154:
Haemolytic Anaemias HAEMOLYTIC ANAE
Page 155 and 156:
Iron chelating drugs iron, aluminiu
Page 157 and 158:
Acute Myelogenous Leukemia (All Tra
Page 159 and 160:
Chronic Lymphocytic Leukemia dyspne
Page 161 and 162:
Antiplatelet drugs Dose: 300 mg in
Page 163 and 164:
Thrombolytic drugs Cost: lnj vial (
Page 165 and 166:
Antifibrinolytics Tranexamic acid P
Page 167 and 168:
Whole Blood/Components Storage and
Page 169 and 170:
Plasma substitutes I: Short-term bl
Page 171 and 172:
Plasma fractions for specific use H
Page 173 and 174:
SECTION 10 CARDIOVASCULAR DRUGS DRU
Page 175 and 176:
Drugs for Angina Dose : Oral : 10 m
Page 177 and 178:
Drugs for Angina I : Angina pectori
Page 179 and 180:
Lipid Lowering Drugs A/E: Reversibl
Page 181 and 182:
Antihypertensive Drugs failure,neph
Page 183 and 184:
Antihypertensive Drugs D/I: Arrhyth
Page 185 and 186:
Antihypertensive Drugs Labetolol I:
Page 187 and 188:
Antihypertensive Drugs Parenteral :
Page 189 and 190:
Antihypertensive Drugs Mainly these
Page 191 and 192:
Antihypertensive Drugs Alpha Methyl
Page 193 and 194:
Antihypertensive Drugs Dose : In hy
Page 195 and 196:
Drugs for Pulmonary Hypertension D/
Page 197 and 198:
Drugs for Heart Failure Dopamine Do
Page 199 and 200:
Anti Arrhythmic Drugs Dose: 250 - 5
Page 201 and 202:
Anti Arrhythmic Drugs enzyme elevat
Page 203 and 204:
Positive inotropic agents Dose : 2.
Page 205 and 206:
Drugs for Superficial Mycosis P/A:
Page 207 and 208:
Drugs for Deep Mycosis D/I: Increas
Page 209 and 210:
Anti Bacterial for Topical Use P/C:
Page 211 and 212:
Drugs used for Psoriasis Dithranol
Page 213 and 214:
Drugs used for Warts P/C: Avoid use
Page 215 and 216:
Drugs for other Dermatological Cond
Page 217 and 218:
Drugs for other Dermatological Cond
Page 219 and 220:
Drugs forLeprosy Rifampicin I: Lepr
Page 221 and 222:
SECTION 12 DIAGNOSTIC AGENTS RADIOC
Page 223 and 224:
Diagnostic agents A/E: Nausea, vomi
Page 225 and 226:
Diagnostic agents reactions;hyperth
Page 227 and 228:
SECTION 13 DISINFECTANTS AND ANTISE
Page 229 and 230:
Disinfectants And Antiseptics ADMIN
Page 231 and 232:
Disinfectants And Antiseptics Gluta
Page 233 and 234:
Loop Diuretics P/A: Dose: Tablets 4
Page 235 and 236:
Osmotic Diuretics D/I: Increases di
Page 237 and 238:
SECTION 15 DRUGS USED IN DENTISTRY
Page 239 and 240:
Drugs for Dentistry STEROIDS Triamc
Page 241 and 242:
Drugs for ENT A/E: P/A: Candidiasis
Page 243 and 244:
Drugs for ENT C/I : Hypersensitivit
Page 245 and 246:
Ulcer Healing Drugs mecamylamine,ps
Page 247 and 248:
Antispasmodics syndrome. Lansoprazo
Page 249 and 250:
Antiemetics And Prokinetics radioth
Page 251 and 252:
Anti Diarrhoeals gastroenteritis an
Page 253 and 254:
Laxatives osteomalacia; complete de
Page 255 and 256:
Drugs Used In Inflammatory Bowel Di
Page 257 and 258:
Drugs Used In Gall Stones and Heamo
Page 259 and 260:
SECTION 18 HORMONES AND OTHER ENDOC
Page 261 and 262:
Adrenal Hormones And Synthetic Subs
Page 263 and 264:
Adrenal Hormones And Synthetic Subs
Page 265 and 266:
Antiandrogens Ointment 2 % w/w, 5 %
Page 267 and 268:
Oestrogens And AntiOestrogens A/E:
Page 269 and 270:
Progestins And Antiprogestins A/E :
Page 271 and 272:
Insulin and Other Anidiabetic Drugs
Page 273 and 274:
Insulin and Other Anidiabetic Drugs
Page 275 and 276:
Thyroid and Anit Thyroid Drugs Cost
Page 277 and 278:
Vitamin D Derivatives orally. Anxie
Page 279 and 280:
Bisphosphonates Dose: Hypercalcemia
Page 281 and 282:
Sera and immunoglobulins Hypersensi
Page 283 and 284:
Vaccines Hepatitis B Immunoglobulin
Page 285 and 286:
Vaccines Dose: Primary immunization
Page 287 and 288:
Vaccines Child:1-15 years: IM, 0.5
Page 289 and 290:
SECTION 20 IMMUNOSUPPRESSANT DRUGS
Page 291 and 292:
Cytotoxic drugs A/E: Hypersensitivi
Page 293 and 294:
Glucocorticoids I : C/I: P/C : A/E:
Page 295 and 296:
Drug treatment of Urolithiasis I: I
Page 297 and 298:
Benign prostatic hypertrophy Terazo
Page 299 and 300:
Urinary Frequency and Enuresis Dose
Page 301 and 302:
Drugs For Impotence A/E : Penile pa
Page 303 and 304:
SECTION 22 MUSCLE RELAXANTS AND ANT
Page 305 and 306:
Central Muscle Relaxants Botulinum
Page 307 and 308:
Peripheral Muscle Relaxant D/I: Sam
Page 309 and 310:
Anticholinesterases C/I: P/C: A/E:
Page 311 and 312:
SECTION 23 OPHTHALMOLOGICAL PREPARA
Page 313 and 314:
Corticosteroids used in Ophthalmolo
Page 315 and 316:
Drug used for Glaucoma Antagonists
Page 317 and 318:
Nutritional Disorders affecting the
Page 319 and 320:
Drugs and Pregnancy Drugs to be avo
Page 321 and 322:
Oxytocics The drip is started with
Page 323 and 324:
Drugs for Induction of Labour PROST
Page 325 and 326:
Drugs for Vaginitis 2. Oral : fluco
Page 327 and 328:
Drugs for Dysfunctional Uterine Ble
Page 329 and 330:
SECTION 25 PSYCHOTHERAPEUTIC DRUGS
Page 331 and 332:
Antipsychotic Drugs Fluphenazine Hy
Page 333 and 334:
Antipsychotic Drugs start initially
Page 335 and 336:
Antipsychotic Drugs dose upto 200 m
Page 337 and 338:
Antipsychotic Drugs Discontinue, if
Page 339 and 340:
Antidepressants reduction of effect
Page 341 and 342:
Antidepressants Doxepin I: Depressi
Page 343 and 344:
Antidepressants Citalopram I, A/E a
Page 345 and 346:
Antidepressants P/C: Renal or hepat
Page 347 and 348:
Anxiolytics C/I: P/C: A/E: P/A: Dos
Page 349 and 350:
Anxiolytics Adjunct in acute alcoho
Page 351 and 352:
Drugs used in substance dependence
Page 353 and 354:
SECTION 26 PAEDIATRIC DRUGS AND NUT
Page 355 and 356:
Paediatric drugs 333
Page 357 and 358:
Page 359 and 360:
Page 361 and 362:
Paediatric drugs Medication >50 % 1
Page 363 and 364:
Paediatric drugs Dicyclomine Hydroc
Page 365 and 366:
Paediatric drugs Terbutaline A/E: T
Page 367 and 368:
Paediatric drugs Amiodarone: A/E :
Page 369 and 370:
Paediatric drugs STATINS Atorvastat
Page 371 and 372:
Paediatric drugs Fosphenytoin P/A:
Page 373 and 374:
Paediatric Nutrition NUTRITION Reco
Page 375 and 376:
Paediatric Nutrition Daily requirem
Page 377 and 378:
Paediatric Nutrition 6. Vitamin K M
Page 379 and 380:
Paediatric Nutrition Calcium Calciu
Page 381 and 382:
Paediatric Nutrition Combination wi
Page 383 and 384:
Drugs for Respiratory Diseases P/A:
Page 385 and 386:
Drugs for Upper Respiratory tract i
Page 387 and 388:
Drugs for Tuberculosis headache, at
Page 389 and 390:
Drugs for Tuberculosis several mont
Page 391 and 392:
Drugs for Asthma and COPD may produ
Page 393 and 394:
Drugs for Tuberculosis Dose: Etophy
Page 395 and 396:
Drugs for Tuberculosis P/A: Inhaler
Page 397 and 398:
Drugs for Tuberculosis Drugs availa
Page 399 and 400:
Cough Suppressants and Mucolytics I
Page 401 and 402:
SECTION 28 SOLUTIONS CORRECTING WAT
Page 403 and 404:
Oral rehydration Salts I : P/C: A/E
Page 405 and 406:
Parental Solutions mmol/litre in 24
Page 407 and 408:
Parental Solutions oedema or water
Page 409 and 410:
Parental Solutions I: pre- and peri
Page 411 and 412:
Total Parental Nutritions solution
Page 413 and 414:
Intravenous access device used for
Page 415 and 416:
Intravenous access device advanced
Page 417 and 418:
Forms of Intravenous Therapy Effect
Page 419 and 420:
Forms of Intravenous Therapy Fluid
Page 421 and 422:
Vitamins and Minerals severe, iodiz
Page 423 and 424:
Vitamins and Minerals be precipitat
Page 425 and 426:
Vitamins and Minerals CHILD 75-125
Page 427 and 428:
Vitamins and Minerals INFANT under
Page 429 and 430:
PART II GUIDELINES FOR FIRST LINE M
Page 431 and 432:
General Topics pulmonary emergencie
Page 433 and 434:
General Topics If the patient is sh
Page 435 and 436:
General Topics DECONTAMINATION The
Page 437 and 438:
General Topics should be monitored.
Page 439 and 440:
General Topics 13. Benzodiazepines
Page 441 and 442:
General Topics FIRST AID 1. Reassur
Page 443 and 444:
General Topics When to repeat ASV A
Page 445 and 446:
General Topics stings should be war
Page 447 and 448:
Paediatrics Dose: 1 packet of ORS d
Page 449 and 450:
Paediatrics 5. fatigue and exhausti
Page 451 and 452:
Paediatrics RECUSCITATION OF NEWBOR
Page 453 and 454:
Paediatrics neurological status. If
Page 455 and 456:
CARDIOLOGY Evaluation of chest pain
Page 457 and 458:
Cardiology ST segment elevation can
Page 459 and 460:
Cardiology Contraindications for be
Page 461 and 462:
Cardiology Cardiac arrest and its m
Page 463 and 464:
Cardiology the procedure so that mo
Page 465 and 466:
Cardiology Approach to treatment de
Page 467 and 468:
Cardiology Adrenergic inhibitors La
Page 469 and 470:
Respiratory System case crystalline
Page 471 and 472:
Respiratory System 3. Acute Iaryngi
Page 473 and 474:
Respiratory System PLEURAL EFFUSION
Page 475 and 476:
Alimentary System comatose. Cardiac
Page 477 and 478:
Alimentary System such as aluminium
Page 479 and 480:
Endocrinology ‣ Tachycardia ‣ H
Page 481 and 482:
Endocrinology Thyroid crisis can be
Page 483 and 484:
NEUROLOGY COMA Coma is one of the m
Page 485 and 486:
Neurology anticonvulsant action of
Page 487 and 488:
OBSTETRICS AND GYNECOLOGY HYPEREMES
Page 489 and 490:
Obstetrics and Gynecology Transfer
Page 491 and 492:
Ophthalmology does not warrant any
Page 493 and 494:
PART III A. LIST OF ESSENTIAL DRUGS
Page 495 and 496:
Primary Care Hospitals 7. ANTIEPILE
Page 497 and 498:
Secondary Care Hospitals 23.IMMUNOL
Page 499 and 500:
Secondary Care Hospitals 44 TERBUTA
Page 501 and 502:
Secondary Care Hospitals 90 GLYCERI
Page 503 and 504:
Taluk Hospitals 140 INSULIN BOVINE,
Page 505 and 506:
Taluk Hospitals 33 METRONIDAZOLE IN
Page 507 and 508:
Taluk Hospitals 7. ANTIDOTES AND OT
Page 509 and 510:
Taluk Hospitals 126 DIGOXIN TAB IP
Page 511 and 512:
Taluk Hospitals 176 DEXTROSE INJ IP
Page 513 and 514:
Tertiary Hospitals 28.VITAMINS & MI
Page 515 and 516:
Tertiary Hospitals 46 AZITHROMYCIN
Page 517 and 518:
Tertiary Hospitals 7. ANTIDOTES AND
Page 519 and 520:
Tertiary Hospitals 145 HEPARIN SODI
Page 521 and 522:
Tertiary Hospitals 19. OPHTHALMIC D
Page 523 and 524:
Tertiary Hospitals 249 HYDROGEN PER
Page 525 and 526:
Tertiary Hospitals 303 FERROUS SULP
Page 527 and 528:
Child Health 1. Progesterone only p
Page 529 and 530:
Diarrhoea Control Programme end of
Page 531 and 532:
National Immunization Schedule 5. N
Page 533 and 534:
National TB Control Programme DOTS
Page 535 and 536:
National Filaria Control Programme
Page 537 and 538:
APPENDIX 1 PREGNANCY During pregnan
Page 539 and 540:
Alcuronium Amitriptyline Amoxyillin
Page 541 and 542:
Didanosine Diethylcarbamazine Doxyc
Page 543 and 544:
Magnesium sulfate Medroxyprogestero
Page 545 and 546:
methaemoglobinaemia; fear of increa
Page 547 and 548:
Table of medicines present in breas
Page 549 and 550:
Gentamicin Hydrochlorothiazide Insu
Page 551 and 552:
dose leaving the normal interval be
Page 553 and 554:
Benzathine penicillin Severe Neurot
Page 555 and 556:
elimination such as clearance and h
Page 557 and 558:
Heparin Hydralazine Hydrochlorothia
Page 559 and 560:
APPENDIX : 6 LIST OF EMERGENCY MEDI
Page 561 and 562:
1. ANAESTHETICS 1.1. General anesth
Page 563 and 564:
4.2. Specific Antisnake Venom U Inj
Page 565 and 566:
Clarithromycin* S,T Capsules 500 mg
Page 567 and 568:
6.4.2.3 Protease inhibitors Indinav
Page 569 and 570:
Etoposide* T Capsules 100mg Injecti
Page 571 and 572:
12. CARDIOVASCULAR MEDICINES 12.1.
Page 573 and 574:
Provide Iodine U Solution or Ointme
Page 575 and 576:
17.2 Antiemetics Domperidone U Tabl
Page 577 and 578:
Norethisterone U Tablets 5 mg 18.8
Page 579 and 580:
Methyl Ergometrine U Tablets 0.125m
Page 581 and 582:
Calcium salts U Tablets 250,500 mg
Page 583 and 584:
Drugs Minimum Maximum Rifampicin 45
Page 585 and 586:
54. Fixed dose combination of Analg
Page 587 and 588:
APPENDIX 8 ADVERSE DRUG EVENT REPOR
Page 589 and 590:
Amiloride .........................
Page 591 and 592:
Bromhexine ........................
Page 593 and 594:
Conjugated oestrogen ..............
Page 595 and 596:
Esmolol ...........................
Page 597 and 598:
Hydrochlorothiazide ...............
Page 599 and 600:
Loxapine ..........................
Page 601 and 602:
Nitrous Oxide .....................
Page 603 and 604:
Povidone iodine ...................
Page 605 and 606:
Sodium Thiosulphate ...............
Page 607:
Vaccines ..........................
show all

Kerala State Drug Formulary.pdf

Create successful ePaper yourself

Delete template?

Save as template?