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Kerala State Drug Formulary.pdf

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Paediatrics<br />

neurological status. If the child is seen soon after ingestion, vomiting<br />

should be induced,by tricking the throat after giving 1 glass of water or<br />

fruit juice.. If induction of emesis is not successful gastric lavage should be<br />

done carefully using a ryles tube. 30 -50 mL water or 1/2 N. saline is<br />

introduced each time and then aspirated until returning fluid is clear.<br />

Specific antidote if available should be given immediately eg. Desferrioxamine<br />

for Iron poisoning. Close observation and masterly inactivity is all that is<br />

required in most cases.<br />

Symptomatic and supportive treatment will be required in all cases.<br />

Severe cases with organ dysfunction should be managed in secondary<br />

care units Therapeutic interventions include treatment of shock,<br />

anticonvulsants, correction of acidosis and fluid-electrolyte balance and<br />

infections .Urinary excretion of poisons like salicylate, and phenobarbitone<br />

can be hastened by forced alkaline diuresis.Haemodialysis may be required<br />

at times. At the time of discharge parents should be advised on prevention<br />

of poisoning<br />

Some Common Poisoning in Children and their Management .<br />

Sl.<br />

No. Poison Clinical features Treatment<br />

1. Acids<br />

Severe pain, erythema and<br />

swelling/ulceration of mouth<br />

Laryngeal oedema-watch for<br />

shock, renal failure<br />

No emetic/lavage<br />

cold water/milk, IVfluid<br />

antibiotic + steroid surgical<br />

consultation<br />

2 Alkali<br />

Pain, swelling, white plaques in<br />

the mouth Dysphagia, drooling<br />

No emetics/lavage. Cold Water<br />

milk IV. fluid, antibiotic<br />

surgical consultation<br />

3. Aspirin<br />

Vomiting, flushing, tinnitus, Lavage/emetics Fluid<br />

abdominal.<br />

electrolyte<br />

Pain, Gl bleed, acidotic breathing therapy. Correct acidosis,<br />

seizure, coma. hypoglycaemia, Glucose, Vit.K, forced alkaline<br />

salicylate level >l00mg/dl. diuresis. Dialysis<br />

in severe poisoning<br />

431

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