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Kerala State Drug Formulary.pdf

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Immunologicals<br />

of child beating age are advised not to become<br />

pregnant for 2 months after vaccination.<br />

A/E: Skin rashes, pharyngitis, fever, lymphadenopathy,<br />

arthralgia, arthropathy, thrombocytopenia and<br />

neurological symptoms including neuropathy and<br />

paraesthesia have been reported rarely<br />

Dose: Adult and Child:12 months and above, deep SC, 0.5mL<br />

as single dose.<br />

Typhoid vaccine<br />

I: Active immunization against typhoid<br />

C/I: Congenital acquired immunodeficiency,treatment with<br />

immunosuppressives and antimitotic drugs; acute<br />

febrile illness,acute intestinal infection<br />

P/C: thrombocytopenia;avoid simultaneous administration<br />

of antibacterials.Mefloquine should not be<br />

taken at least 12 hours before or after a dose<br />

A/E: Redness pain and swelling, fever, headache, malaise,<br />

nausea, itching, rarely anaphylaxis<br />

Dose: Adult:IM single dose of 0.5 ml,revaccinated every 3<br />

years if necessary<br />

Child:>2 years, same as adult dose<br />

Cholera vaccine<br />

I: Active immunization against cholera<br />

C/I: Hypersensitivity to previous dose<br />

P/C: Immunity last only upto 6 months,hence attention to<br />

hygiene food and water is essential<br />

A/E: Mild transient gastrointestinal disturbances reported<br />

Dose: Adult 0.5 ml IM second dose after 4 weeks 1 ml IM;<br />

Child 1-5 years 0.1ml second dose 0.3 ml;<br />

6-10 years,0.3 ml,second dose 0.5 ml<br />

Hepatitis A vaccine<br />

I: active immunization against hepatitis A virus infection<br />

C/I: Hypersensitivity<br />

P/C: Serious infections,cardiovascular disease pulmonary<br />

disorders pregnancy,breast feeding<br />

A/E: Fatigue,fever,transient LFT abnormalities, headache,<br />

reactions at injection sites rarely<br />

Dose: Adult:IM,1 ml as a single dose;and a booster dose 1 ml<br />

6-12 months after usual dose<br />

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