Kerala State Drug Formulary.pdf

Pencillins
Phenoxymethyl penicillin (Penicillin V)
Dose: 500 mg every 6 hours orally,increase upto 750 mg in
severe infections.
Cost: 250 mg (10) Rs:13.50/-
Beta lactamase resistant penicillins
Cloxacillin
I: Infections due to penicillinase resistant staphylococci
C/I: P/C: A/E: D/I: Similar to that of Benzyl penicillin
P/A: Capsules 250 mg, 500 mg, Injection 250 mg, 500
mg(Powder for reconstitution) Combination
preparations (tablet, injection, syrup) with ampicillin
in different ratios are available.
Dose: 250-500 mg orally 4 times daily half an hour before
food;250 mg IM every 4-6 hours;500 mg slow IV every
4-6 hours.
Cost: Caps 500 mg (10) Rs. 63.00; Injection 250 mg (1 vial)
Rs. 6.00 -10.00
Broad spectrum penicillins
Spectrum of Penicillin G + activity against g –ve bacteria
Ampicillin
I: Urinary tract infection, respiratory tract
infections,otitis media,sinusitis,chronic bronchitis,
invasive salmonellosis and gonorrhea.
C/l: Penicillin hypersensitivity
P/C: D/I: As for of benzyl penicillin.
A/E: As for of benzyl penicillin;nausea,diarrhoea,rashes
P/A: Capsules 250 mg, 500 mg
Injection 500 mg/vial (Powder for reconstitution)
Dose : 250 mg-1 g 6 hourly atleast 30 minutes before or 2
hours after food;500 mg IM/slow IV every 4-6 hours
Cost: Caps 250mg (10) Rs. 32.00 - 36.00
Injection 500 mg (vial) Rs.10.00 - 23.00
Ampicillin + Sulbactam
I: Infections caused by beta lactamase producing
organisms
P/A: Injection Ampicillin1g + Sulbactam 0.5g
Dose: 1.5 – 3 g IV/deep IM 6-8 hourly
Cost: Injection Ampicillin1g + Sulbactam 0.5g vial
Rs. 78.00 – 110.00
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