Kerala State Drug Formulary.pdf

Psychotherapeutic Drugs
P/A: Tablets 2mg, 5 mg, 10 mg Capsule 2mg, 5mg, 10 mg,
Injection 5mg/ mL. Injection (emulsion) 5mg/ mL for
i.v. injection or as infusion.
Dose: Anxiety Oral - 2 mg tds increased if necessary to
15-30 mg od in divided doses; Elderly half the adult
dose; Insomnia associated with anxiety 5-15 mg hs;
Children with night terrors and somnabulism, 1-5 mg
hs Parenteral - slow IV injection into a large vein at a
rate of not more than 5 mg/ min, for the management
of severe acute anxiety, control of acute panic
attacks, and acute alcohol withdrawal. 10 mg may be
repeated, if necessary after 4 h. Injection (IM) canbe
given but absorption from the site is erratic and the
are unpredictable. Rectal — for acute anxiety and
agitation, as rectal solution or suppositories 10 mg. If
necessary a further 10mg may be given after at least
10 min.; elderly 5 mg.
D / I: Isoniazid, omeprazole and disulfiram inhibit metabolism
of diazepam and other benzodiazepines.
Benzodiazepines antagonise the effect of levodopa.
Cost : Tab 10 mg (10) Rs. 4.00 — 24.00 Cap10 mg (10) Rs. 12.
00- 13.00 Inj 5 mg/mL ( 2 mL) Rs. 10.00
Alprazolam
I: For the short term management of anxiety states.
C/I, P/C, A/E: Same as for diazepam.
P/A: Tablets 0.25 mg, 0.5 mg, I mg Sustained Release (SR)
1.5 mg
Dose: 0.25-0.5 mg tds, Elderly 250 mcg bd — tds, increased
if necessary to a total of 3 mg
D/I: Same as for diazepam
Cost: Tab 0.5 mg (10) Rs. 14.00 — 15.00
Chlordiazepoxide
I: For short term use in anxiety. Adjunct in acute alcohol
withdrawal symptoms.
C/I, P/C, A/E, D/I: Same as diazepam.
P/A: Tablets 10 mg and 25 mg
Dose: Anxiety 10 mg tds increased if necessary to 60-100 mg
od in divided doses; For elderly half adult dose.
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