Kerala State Drug Formulary.pdf

Antipsychotic Drugs
Fluphenazine Hydrochloride
I: Schizhophrenia and other psychoses, mania, short
term adjunctive management of severe anxiety,
psychomotor agitation, excitement and violent,
dangerously impulsive behaviour.
C/l, P/C, A/E, D/I: Same as for chlorpromazine.
P/A: Tablet 1 mg, 2.5 mg, 5 mg, Injection 25 mg /mL contain
oily solution of fluphenazine decanoate for depot use.
Dose: Schizophrenia and other psychoses Oral : 2.5 -10 mg
od in 2-3 divided doses; adjusted according to
response to 20 mg od; doses above 20 mg (10 mg in
elderly) should be given cautiously. Parenteral: 25 mg
as deep IM injection once in 2 - 4 weeks. Anxiety,
agitation and excitement Oral: initially 1 mg bd,
increased as necessary to 2 mg bd.
Cost : Inj 25 mg/ml. (1 mL) Rs. 26.90-29.90
Prochlorperazine
I: Schizophrenia and other psychoses, mania, severe
anxiety, nausea, vomiting, vertigo, labyrinthine
disorders.
C/I, P/C, A/E, D/l: Same as for chlorpromazine.
P/A: Tablets 5 mg, 25mg Injection 12.5 mg/mL.
Dose: Schizophrenia and other psychosis
Oral: Mania: start with 12.5 mg bd for 7 days and adjust at
intervals of 4-7 days to reach the usual dose of 75-100
mg od according to response;
Anxiety: 15 to 20 mg od in divided doses upto a
maximum of 40 mg.
Parenteral: IM 12.5 mg initially and followed if
necessary after 6 hours an oral dose. Labyrinthine
disorders: 5 mg t.d.s., gradually increased upto 30 mg
od and then reduced after several weeks to the
maintenance dose of 5-10 mg od
Cost: Tab 5 mg (10) Rs. 8.00 - 9.00 lnj 12.5 mg/mL (10 mL) Rs.
40.00 - 43.00
Haloperidol
I: Schizophrenia and other psychoses, mania, short term
adjunctive management of psychomotor agitation,
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