Kerala State Drug Formulary.pdf

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Gastrointestinal <strong>Drug</strong>s P/A : Tablet 150 mg Dose : 8 - 10 mg/kg/day in divided doses, taken with meals. ANTIHAEMORRHOIDAL DRUGS Haemorrhoids are to be treated surgically for complete relief.Symptomatic treatment for constipation, local pain, discomfort, inflammation are managed medically. A mild laxative such as liquid paraffin or bulk laxative such as Ispaghula helps to soften the faeces.Inflammation is to be treated with antibacterial agents such as Ciprofloxacin or Amoxicillin. Pain relief is obtained by a NSAID such as diclofenac or Ibuprofen P/A : Anovate to be applied twice a day once following defaecation and once at bed time . Cost : Anovate 15 g - Rs. 9.70; 20 gms - Rs.49.56; Shield 15 g Rs 45 .00 236
SECTION 18 HORMONES AND OTHER ENDOCRINE DRUGS ADRENAL HORMONES AND SYNTHETIC SUBSTANCES The adrenal hormones are steroids synthesized from cholestrerol derived from the diet. The main groups of hormones are glucocorticoids (cortisol), mineralocorticoids (aldosterone) and adrenal androgens. (dehydroepiandrosterone) each produced in a specific zone of the cortex. At present all the available adrenal hormones are synthetic. Glucocoricoids Short acting Hydrocortisone Intermediate acting Prednisolone Methyl Prednisolone Triamcinolone Long Acting Betamethasone Dexamethasone Mineralocorticoids Deoxycorticosterone acetate Fludrocortisone Prednisolone I : Suppression of inflammatory and allergic disorders. asthma ,immunosuppression, rheumatic disease. C/I : Systemic infection; avoid live virus vaccines in those receiving immunosuppressive doses P/C : Adrenal suppression, children and adolescents, elderly; frequent monitoring required if history of tuberculosis, hypertension,myocardial infarction, congestive heart failure, liver failure, impairment, diabetes mellitus, osteoporosis, glaucoma, epilepsy,ulcer, hypothyroidism, history of steroid myopathy; pregnancy and breast feeding, avoid sudden withdrawal. 237
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KERALA STATE DRUG FORMULARY NUMBER
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CENTRAL DRUG FORMULARY COMMITTEE CH
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LIST OF CONTRIBUTORS 1. Dr. K.V. Kr
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FOREWORD Medicines play a crucial r
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Dr. V. Geetha, Director of Medical
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ABBREVIATIONS A/E .................
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Antiretroviral drugs ..............
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Dyes used in ophthalmology ........
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Antipsychotic drugs ...............
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Eclampsia .........................
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PART - I GENERAL ADVICE TO PRESCRIB
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General advice to Prescribers Monit
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General advice to Prescribers Pharm
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General advice to Prescribers refil
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General advice to Prescribers neces
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General advice to Prescribers 2C19
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General advice to Prescribers possi
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General advice to Prescribers Cost
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General advice to Prescribers Did w
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Inhalational agents I:, C/I:,D/I: s
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Intravenous General Anaesthetics Re
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Local Anaesthetics anaesthesia. Low
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Local Anaesthetics A/E: P/A: Dose:
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Preoperative Medication PREOPERATIV
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Preoperative Medication A/E: P/A: D
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SECTION - 2 ANALGESICS, ANTIPYRETIC
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Non-Steroidal Anti-Inflammatory Dru
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Opioid Analgesics P/A : Injection:
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Opioid Analgesics pain, 100 mg init
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Drugs in Rheumatoid Disorders P/A:
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Drugs in Rheumatoid Disorders IMPOR
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Medicines used for Gout Dose: Admin
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SECTION - 3 ANTI CONVULSANTS/ANTIEP
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Antiepileptics A/E: Cardiovascular
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Antiepileptics Ethosuximide I: Drug
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Antiepileptics hypotonia, coordinat
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Antiepileptics Topiramate I: Adjunc
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Antiepileptics Felbamate I: Unrespo
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SECTION - 4 ANTIINFECTIVE DRUGS ANT
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Pencillins Phenoxymethyl penicillin
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Cephalosporins Cephazolin I: Surgic
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Pencillins Cefdinir I: Pneumonia, c
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Aminoglycosides Gentamicin I: Urina
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Broad spectrum antibiotics I: Ricke
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Macrolides pertussis, endemic trach
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Macrolides photosensitivity; hepati
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Teicoplanin Cost: Tab 50 mg (10) Rs
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Fluoroquinolones A/E: Nausea, epiga
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Sulphonamides A/E: same as in cipro
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Antifungal drugs Sulphacetamide I:
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Antiviral drugs ANTI VIRAL DRUGS An
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Non selective antiviral drugs Dose:
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Antiretroviral drugs Dose: Oral, 30
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Antiretroviral drugs A/E : Rash inc
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Antimalarial drugs Artesunate I: Ml
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Antimalarial drugs Quinine I: Acts
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Antiamoebic and other protozoal dru
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Anthelmintics drugs Other drugs use
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Antifilarial drugs SCHISTOSOMICIDES
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SECTION - 5 ANTIMIGRAINE MEDICINES
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SECTION 6 ANTINEOPLASTIC DRUGS ALKY
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Antimetabolites Cost : Inj: 1 g via
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Antineoplastic Drugs Cost : 5-Fluor
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Cytotoxis Antibiotics P/A: Injectio
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Mitotic Inhibitors Epirubicin I: Ca
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Hormones and Hormonal antagonists P
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Targeted agents Progestins Medroxy
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Cytoprotective agents A/E: Infusion
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Dopaminergic agonist P/A: Dose: Bro
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MAO B Inhibitor MAO B Inhibitor Sel
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Central Anticholinergics daily (wit
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SECTION - 8 DRUGS ACTING ON BLOOD A
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Drug affecting Coagulation P/C: Can
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Haemolytic Anaemias HAEMOLYTIC ANAE
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Iron chelating drugs iron, aluminiu
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Acute Myelogenous Leukemia (All Tra
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Chronic Lymphocytic Leukemia dyspne
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Antiplatelet drugs Dose: 300 mg in
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Thrombolytic drugs Cost: lnj vial (
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Antifibrinolytics Tranexamic acid P
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Whole Blood/Components Storage and
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Plasma substitutes I: Short-term bl
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Plasma fractions for specific use H
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SECTION 10 CARDIOVASCULAR DRUGS DRU
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Drugs for Angina Dose : Oral : 10 m
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Drugs for Angina I : Angina pectori
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Lipid Lowering Drugs A/E: Reversibl
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Antihypertensive Drugs failure,neph
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Antihypertensive Drugs D/I: Arrhyth
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Antihypertensive Drugs Labetolol I:
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Antihypertensive Drugs Parenteral :
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Antihypertensive Drugs Mainly these
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Antihypertensive Drugs Alpha Methyl
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Antihypertensive Drugs Dose : In hy
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Drugs for Pulmonary Hypertension D/
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Drugs for Heart Failure Dopamine Do
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Anti Arrhythmic Drugs Dose: 250 - 5
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Anti Arrhythmic Drugs enzyme elevat
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Positive inotropic agents Dose : 2.
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Drugs for Superficial Mycosis P/A:
Page 207 and 208: Drugs for Deep Mycosis D/I: Increas
Page 209 and 210: Anti Bacterial for Topical Use P/C:
Page 211 and 212: Drugs used for Psoriasis Dithranol
Page 213 and 214: Drugs used for Warts P/C: Avoid use
Page 215 and 216: Drugs for other Dermatological Cond
Page 217 and 218: Drugs for other Dermatological Cond
Page 219 and 220: Drugs forLeprosy Rifampicin I: Lepr
Page 221 and 222: SECTION 12 DIAGNOSTIC AGENTS RADIOC
Page 223 and 224: Diagnostic agents A/E: Nausea, vomi
Page 225 and 226: Diagnostic agents reactions;hyperth
Page 227 and 228: SECTION 13 DISINFECTANTS AND ANTISE
Page 229 and 230: Disinfectants And Antiseptics ADMIN
Page 231 and 232: Disinfectants And Antiseptics Gluta
Page 233 and 234: Loop Diuretics P/A: Dose: Tablets 4
Page 235 and 236: Osmotic Diuretics D/I: Increases di
Page 237 and 238: SECTION 15 DRUGS USED IN DENTISTRY
Page 239 and 240: Drugs for Dentistry STEROIDS Triamc
Page 241 and 242: Drugs for ENT A/E: P/A: Candidiasis
Page 243 and 244: Drugs for ENT C/I : Hypersensitivit
Page 245 and 246: Ulcer Healing Drugs mecamylamine,ps
Page 247 and 248: Antispasmodics syndrome. Lansoprazo
Page 249 and 250: Antiemetics And Prokinetics radioth
Page 251 and 252: Anti Diarrhoeals gastroenteritis an
Page 253 and 254: Laxatives osteomalacia; complete de
Page 255 and 256: Drugs Used In Inflammatory Bowel Di
Page 257: Drugs Used In Gall Stones and Heamo
Page 261 and 262: Adrenal Hormones And Synthetic Subs
Page 263 and 264: Adrenal Hormones And Synthetic Subs
Page 265 and 266: Antiandrogens Ointment 2 % w/w, 5 %
Page 267 and 268: Oestrogens And AntiOestrogens A/E:
Page 269 and 270: Progestins And Antiprogestins A/E :
Page 271 and 272: Insulin and Other Anidiabetic Drugs
Page 273 and 274: Insulin and Other Anidiabetic Drugs
Page 275 and 276: Thyroid and Anit Thyroid Drugs Cost
Page 277 and 278: Vitamin D Derivatives orally. Anxie
Page 279 and 280: Bisphosphonates Dose: Hypercalcemia
Page 281 and 282: Sera and immunoglobulins Hypersensi
Page 283 and 284: Vaccines Hepatitis B Immunoglobulin
Page 285 and 286: Vaccines Dose: Primary immunization
Page 287 and 288: Vaccines Child:1-15 years: IM, 0.5
Page 289 and 290: SECTION 20 IMMUNOSUPPRESSANT DRUGS
Page 291 and 292: Cytotoxic drugs A/E: Hypersensitivi
Page 293 and 294: Glucocorticoids I : C/I: P/C : A/E:
Page 295 and 296: Drug treatment of Urolithiasis I: I
Page 297 and 298: Benign prostatic hypertrophy Terazo
Page 299 and 300: Urinary Frequency and Enuresis Dose
Page 301 and 302: Drugs For Impotence A/E : Penile pa
Page 303 and 304: SECTION 22 MUSCLE RELAXANTS AND ANT
Page 305 and 306: Central Muscle Relaxants Botulinum
Page 307 and 308: Peripheral Muscle Relaxant D/I: Sam
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Anticholinesterases C/I: P/C: A/E:
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SECTION 23 OPHTHALMOLOGICAL PREPARA
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Corticosteroids used in Ophthalmolo
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Drug used for Glaucoma Antagonists
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Nutritional Disorders affecting the
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Drugs and Pregnancy Drugs to be avo
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Oxytocics The drip is started with
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Drugs for Induction of Labour PROST
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Drugs for Vaginitis 2. Oral : fluco
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Drugs for Dysfunctional Uterine Ble
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SECTION 25 PSYCHOTHERAPEUTIC DRUGS
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Antipsychotic Drugs Fluphenazine Hy
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Antipsychotic Drugs start initially
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Antipsychotic Drugs dose upto 200 m
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Antipsychotic Drugs Discontinue, if
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Antidepressants reduction of effect
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Antidepressants Doxepin I: Depressi
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Antidepressants Citalopram I, A/E a
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Antidepressants P/C: Renal or hepat
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Anxiolytics C/I: P/C: A/E: P/A: Dos
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Anxiolytics Adjunct in acute alcoho
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Drugs used in substance dependence
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SECTION 26 PAEDIATRIC DRUGS AND NUT
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Paediatric drugs 333
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Paediatric drugs Medication >50 % 1
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Paediatric drugs Dicyclomine Hydroc
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Paediatric drugs Terbutaline A/E: T
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Paediatric drugs Amiodarone: A/E :
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Paediatric drugs STATINS Atorvastat
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Paediatric drugs Fosphenytoin P/A:
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Paediatric Nutrition NUTRITION Reco
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Paediatric Nutrition Daily requirem
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Paediatric Nutrition 6. Vitamin K M
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Paediatric Nutrition Calcium Calciu
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Paediatric Nutrition Combination wi
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Drugs for Respiratory Diseases P/A:
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Drugs for Upper Respiratory tract i
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Drugs for Tuberculosis headache, at
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Drugs for Tuberculosis several mont
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Drugs for Asthma and COPD may produ
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Drugs for Tuberculosis Dose: Etophy
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Drugs for Tuberculosis P/A: Inhaler
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Drugs for Tuberculosis Drugs availa
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Cough Suppressants and Mucolytics I
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SECTION 28 SOLUTIONS CORRECTING WAT
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Oral rehydration Salts I : P/C: A/E
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Parental Solutions mmol/litre in 24
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Parental Solutions oedema or water
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Parental Solutions I: pre- and peri
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Total Parental Nutritions solution
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Intravenous access device used for
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Intravenous access device advanced
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Forms of Intravenous Therapy Effect
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Forms of Intravenous Therapy Fluid
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Vitamins and Minerals severe, iodiz
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Vitamins and Minerals be precipitat
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Vitamins and Minerals CHILD 75-125
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Vitamins and Minerals INFANT under
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PART II GUIDELINES FOR FIRST LINE M
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General Topics pulmonary emergencie
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General Topics If the patient is sh
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General Topics DECONTAMINATION The
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General Topics should be monitored.
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General Topics 13. Benzodiazepines
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General Topics FIRST AID 1. Reassur
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General Topics When to repeat ASV A
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General Topics stings should be war
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Paediatrics Dose: 1 packet of ORS d
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Paediatrics 5. fatigue and exhausti
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Paediatrics RECUSCITATION OF NEWBOR
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Paediatrics neurological status. If
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CARDIOLOGY Evaluation of chest pain
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Cardiology ST segment elevation can
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Cardiology Contraindications for be
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Cardiology Cardiac arrest and its m
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Cardiology the procedure so that mo
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Cardiology Approach to treatment de
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Cardiology Adrenergic inhibitors La
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Respiratory System case crystalline
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Respiratory System 3. Acute Iaryngi
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Respiratory System PLEURAL EFFUSION
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Alimentary System comatose. Cardiac
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Alimentary System such as aluminium
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Endocrinology ‣ Tachycardia ‣ H
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Endocrinology Thyroid crisis can be
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NEUROLOGY COMA Coma is one of the m
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Neurology anticonvulsant action of
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OBSTETRICS AND GYNECOLOGY HYPEREMES
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Obstetrics and Gynecology Transfer
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Ophthalmology does not warrant any
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PART III A. LIST OF ESSENTIAL DRUGS
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Primary Care Hospitals 7. ANTIEPILE
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Secondary Care Hospitals 23.IMMUNOL
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Secondary Care Hospitals 44 TERBUTA
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Secondary Care Hospitals 90 GLYCERI
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Taluk Hospitals 140 INSULIN BOVINE,
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Taluk Hospitals 33 METRONIDAZOLE IN
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Taluk Hospitals 7. ANTIDOTES AND OT
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Taluk Hospitals 126 DIGOXIN TAB IP
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Taluk Hospitals 176 DEXTROSE INJ IP
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Tertiary Hospitals 28.VITAMINS & MI
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Tertiary Hospitals 46 AZITHROMYCIN
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Tertiary Hospitals 7. ANTIDOTES AND
Page 519 and 520:
Tertiary Hospitals 145 HEPARIN SODI
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Tertiary Hospitals 19. OPHTHALMIC D
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Tertiary Hospitals 249 HYDROGEN PER
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Tertiary Hospitals 303 FERROUS SULP
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Child Health 1. Progesterone only p
Page 529 and 530:
Diarrhoea Control Programme end of
Page 531 and 532:
National Immunization Schedule 5. N
Page 533 and 534:
National TB Control Programme DOTS
Page 535 and 536:
National Filaria Control Programme
Page 537 and 538:
APPENDIX 1 PREGNANCY During pregnan
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Alcuronium Amitriptyline Amoxyillin
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Didanosine Diethylcarbamazine Doxyc
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Magnesium sulfate Medroxyprogestero
Page 545 and 546:
methaemoglobinaemia; fear of increa
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Table of medicines present in breas
Page 549 and 550:
Gentamicin Hydrochlorothiazide Insu
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dose leaving the normal interval be
Page 553 and 554:
Benzathine penicillin Severe Neurot
Page 555 and 556:
elimination such as clearance and h
Page 557 and 558:
Heparin Hydralazine Hydrochlorothia
Page 559 and 560:
APPENDIX : 6 LIST OF EMERGENCY MEDI
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1. ANAESTHETICS 1.1. General anesth
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4.2. Specific Antisnake Venom U Inj
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Clarithromycin* S,T Capsules 500 mg
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6.4.2.3 Protease inhibitors Indinav
Page 569 and 570:
Etoposide* T Capsules 100mg Injecti
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12. CARDIOVASCULAR MEDICINES 12.1.
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Provide Iodine U Solution or Ointme
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17.2 Antiemetics Domperidone U Tabl
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Norethisterone U Tablets 5 mg 18.8
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Methyl Ergometrine U Tablets 0.125m
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Calcium salts U Tablets 250,500 mg
Page 583 and 584:
Drugs Minimum Maximum Rifampicin 45
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54. Fixed dose combination of Analg
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APPENDIX 8 ADVERSE DRUG EVENT REPOR
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Amiloride .........................
Page 591 and 592:
Bromhexine ........................
Page 593 and 594:
Conjugated oestrogen ..............
Page 595 and 596:
Esmolol ...........................
Page 597 and 598:
Hydrochlorothiazide ...............
Page 599 and 600:
Loxapine ..........................
Page 601 and 602:
Nitrous Oxide .....................
Page 603 and 604:
Povidone iodine ...................
Page 605 and 606:
Sodium Thiosulphate ...............
Page 607:
Vaccines ..........................
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