Kerala State Drug Formulary.pdf

Hormones and other endocrine drugs
6 hours as required for 2-10 days.In severe shock:
(as dexamethasone phosphate), IM 2-6mg/kg repeated
after 2-6 hours if necessary.CHILD: IV/IM, 250-
500mcg/kg (as dexamethasone phosphate) once daily.
Note: Dexamethasone lmg=Dexamethasone phosphate 1.2mg
= Dexamethasone sodium phosphate 1.3mg.
COST: 0.5 mg(10) Rs 2-4 ;Inj 4 mg/ml (2 ml) Rs 7-11;
Hydrocortisone acetate
I: Adrenocortical insufficiency, supression of inflammatory
and allergic disorders, shock and rheumatic disease.
C/I: As for prednisolone
P/C: As for prednisolone
A/E: As for prednisolone
P/A: Injection, 25mg/ml, 5ml vials.
Dose : ADULT: Intra-articular,(as acetate), 5-50mg depending
on size of joint. CHILD : Replacement therapy, oral,
4mg/m 2 , 3 times a day.
Hydrocortisone Sodium Succinate
I : Adrenocortical insufficiency, shock, hypersensitivity
reactions(anaphylactic shock and angioedema), acute
severe asthma.
C/I: As for prednisolone
P/C: As for prednisolone
A/E: As for Prednisolone
P/A: Tablets (as hydrocortisone), 5mg, 10mg, 20mg.
Injection (as sodium succinate), 100mg/vial (powder
for reconstitution).
DOSE : ADULT: As hydrocortisone, I.M/IV 100-500mg 3-4 times
in 24 hours ;or as required.
CHILD: Oral, 4mg/m 2 three times daily.Slow IV upto 1 year
25mg; 1-5 years, 50mg; 6-12 years 100mg.
Cost : 100mg vial Rs 32- 60/-
Triamcinolone Acetonide
I : Suppression of inflammatory and allergic disorders.
C/I : As for prednisolone
P/C : As for prednisolone, high doses may cause proximal
myopathy, avoid in chronic therapy.
A/E : As for prednisolone
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