Kerala State Drug Formulary.pdf

Guidelines
8. Methyl alcohol Ethyl alcohol Correction of metabolic
acidosis by sodium
bicarbonate 0.6-0.7g/kg
IV diluted or oral, ethanol
should be given orally in a
dose of 30-50 mL in 2-4 h,
if blood level of methanol
exceeds 20mg/dl
Hemodialysis to remove
methyl alcohol if blood
level >0.5g/L or total
quantity
ingested>30mL.Peritoneal
dialysis only 1/8 th
effective as
haemodialysis.
9. Nitrites Methylene blue 1-2mg/kg of 1% solution
solution IV
10.Opiates Naloxone 0-4-2mg IV
11.Organophosphates Atropine
Pralidoxime
12. Carbamates Atropine
Glycopyrrolate
15mg IV every 15 min till
drying of secretions.
1 g IV over 15-30 min 8 h
2-3 mg parenterally and
repeat until signs of
atropine intoxication
appears
It is an effective antidote
It is available as ampoules
containing 2mg of the drug
to be given in a dose of
0.45 mg per kg body wt IM
or IV to be repeated till
symptoms are
relieved.this drug is
devoid of CNS side effects
of atropine
Early
management
may be
successful
May need
exchange
Administration
has to be
continuous drip
to maintain
pupil size
normal.very
large doses of
250 -750
ampoules may
be required for
saving serious
cases
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