Kerala State Drug Formulary.pdf

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Guidelines h) Oxygen inhalation and other treatment modes like antibiotics, alkali therapy, and I.V fluid if indicated. No sedation, but monitor carefully. Very few cases may need artificial ventilation to save life ASTHMA IN CHILDREN < 5 YEARS OF AGE Step Long term control Quick Relief Step 4 Severe Persistent High dose inhaled steroid with Bronchodilator as spacer. If needed add systemic needed for symptom steroids 2 mg/kg/day relief upto three times a day Step 3 Moderate persistent Medium dose inhaled steroid “ “ with spacer OR medium dose inhaled steroid with cromolyn OR medium dose inhaled steroid with long acting theophylline Step 2 Mild persistent Daily anti-inflammatory medication “ “ either inhaled cromolyn or low dose inhaled steroids Step1 Mild intermittent No daily medication needed Bronchodilator as needed for symptom relief-either inhaled short acting beta 2 agonist with spacer or oral beta 2 agonists 428
Paediatrics RECUSCITATION OF NEWBORN • Evaluate the neonate at birth for adequacy of respiration, heart rate and colour. • Most newborn babies cry immediately at birth. Dry the baby in a clean warm towel.one of the most accepted objective method to initate recuscitative procedure is to determine the Apgar score which is given below Score 0 1 2 Respiratory None Slow irregular Good, crying effort Heart rate/ min Absent 100 Colour of the Blue or pale Body pink, Pink baby extremities blue Muscle tone Flaccid Some flexion Actively moving the extremities Reflex stimulation (catheter in the nose) No response Grimace Cries,coughs or sneezes Normal babies have an apgar score of more than 8 at 1 & 5 min. Apgar score between 4-8 is moderately low while that less than 4 is very low 5 min apgar score is more important that 1 min apgar score • If baby has not cried within 15-20 seconds after birth or if baby is apnoeic or gasping, place the baby on a flat resuscitation table under a warmer with head slightly extended by 30 degrees. • Clean the airway by oropharyngeal suction, mouth first, then nose. ° Provide tactile stimulus by flicking the soles. • Do not slap the baby or hang him upside down. • If baby is still gasping/apnoeic immediately initiate assisted ventilation with a bag and mask using oxygen at 2-4 L/min. Use of oxygen reservoir will enable 100% oxygen administration. • Count heart rate with a stethoscope for 6 seconds and multiply by 10 to get heart rate in 1 minute. • If heart rate is less than 60 or fails to rise above 80 after 30 seconds of assisted ventilation, then initiate external cardiac massage by chest compression 120 times a minute. For every 2 chest compression one ventilatory breath is given. 429
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KERALA STATE DRUG FORMULARY NUMBER
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CENTRAL DRUG FORMULARY COMMITTEE CH
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LIST OF CONTRIBUTORS 1. Dr. K.V. Kr
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FOREWORD Medicines play a crucial r
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Dr. V. Geetha, Director of Medical
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ABBREVIATIONS A/E .................
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Antiretroviral drugs ..............
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Dyes used in ophthalmology ........
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Antipsychotic drugs ...............
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Eclampsia .........................
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PART - I GENERAL ADVICE TO PRESCRIB
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General advice to Prescribers Monit
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General advice to Prescribers Pharm
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General advice to Prescribers refil
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General advice to Prescribers neces
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General advice to Prescribers 2C19
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General advice to Prescribers possi
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General advice to Prescribers Cost
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General advice to Prescribers Did w
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Inhalational agents I:, C/I:,D/I: s
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Intravenous General Anaesthetics Re
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Local Anaesthetics anaesthesia. Low
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Local Anaesthetics A/E: P/A: Dose:
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Preoperative Medication PREOPERATIV
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Preoperative Medication A/E: P/A: D
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SECTION - 2 ANALGESICS, ANTIPYRETIC
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Non-Steroidal Anti-Inflammatory Dru
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Opioid Analgesics P/A : Injection:
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Opioid Analgesics pain, 100 mg init
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Drugs in Rheumatoid Disorders P/A:
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Drugs in Rheumatoid Disorders IMPOR
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Medicines used for Gout Dose: Admin
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SECTION - 3 ANTI CONVULSANTS/ANTIEP
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Antiepileptics A/E: Cardiovascular
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Antiepileptics Ethosuximide I: Drug
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Antiepileptics hypotonia, coordinat
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Antiepileptics Topiramate I: Adjunc
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Antiepileptics Felbamate I: Unrespo
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SECTION - 4 ANTIINFECTIVE DRUGS ANT
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Pencillins Phenoxymethyl penicillin
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Cephalosporins Cephazolin I: Surgic
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Pencillins Cefdinir I: Pneumonia, c
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Aminoglycosides Gentamicin I: Urina
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Broad spectrum antibiotics I: Ricke
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Macrolides pertussis, endemic trach
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Macrolides photosensitivity; hepati
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Teicoplanin Cost: Tab 50 mg (10) Rs
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Fluoroquinolones A/E: Nausea, epiga
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Sulphonamides A/E: same as in cipro
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Antifungal drugs Sulphacetamide I:
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Antiviral drugs ANTI VIRAL DRUGS An
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Non selective antiviral drugs Dose:
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Antiretroviral drugs Dose: Oral, 30
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Antiretroviral drugs A/E : Rash inc
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Antimalarial drugs Artesunate I: Ml
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Antimalarial drugs Quinine I: Acts
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Antiamoebic and other protozoal dru
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Anthelmintics drugs Other drugs use
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Antifilarial drugs SCHISTOSOMICIDES
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SECTION - 5 ANTIMIGRAINE MEDICINES
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SECTION 6 ANTINEOPLASTIC DRUGS ALKY
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Antimetabolites Cost : Inj: 1 g via
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Antineoplastic Drugs Cost : 5-Fluor
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Cytotoxis Antibiotics P/A: Injectio
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Mitotic Inhibitors Epirubicin I: Ca
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Hormones and Hormonal antagonists P
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Targeted agents Progestins Medroxy
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Cytoprotective agents A/E: Infusion
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Dopaminergic agonist P/A: Dose: Bro
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MAO B Inhibitor MAO B Inhibitor Sel
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Central Anticholinergics daily (wit
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SECTION - 8 DRUGS ACTING ON BLOOD A
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Drug affecting Coagulation P/C: Can
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Haemolytic Anaemias HAEMOLYTIC ANAE
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Iron chelating drugs iron, aluminiu
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Acute Myelogenous Leukemia (All Tra
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Chronic Lymphocytic Leukemia dyspne
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Antiplatelet drugs Dose: 300 mg in
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Thrombolytic drugs Cost: lnj vial (
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Antifibrinolytics Tranexamic acid P
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Whole Blood/Components Storage and
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Plasma substitutes I: Short-term bl
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Plasma fractions for specific use H
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SECTION 10 CARDIOVASCULAR DRUGS DRU
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Drugs for Angina Dose : Oral : 10 m
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Drugs for Angina I : Angina pectori
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Lipid Lowering Drugs A/E: Reversibl
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Antihypertensive Drugs failure,neph
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Antihypertensive Drugs D/I: Arrhyth
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Antihypertensive Drugs Labetolol I:
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Antihypertensive Drugs Parenteral :
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Antihypertensive Drugs Mainly these
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Antihypertensive Drugs Alpha Methyl
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Antihypertensive Drugs Dose : In hy
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Drugs for Pulmonary Hypertension D/
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Drugs for Heart Failure Dopamine Do
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Anti Arrhythmic Drugs Dose: 250 - 5
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Anti Arrhythmic Drugs enzyme elevat
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Positive inotropic agents Dose : 2.
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Drugs for Superficial Mycosis P/A:
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Drugs for Deep Mycosis D/I: Increas
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Anti Bacterial for Topical Use P/C:
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Drugs used for Psoriasis Dithranol
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Drugs used for Warts P/C: Avoid use
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Drugs for other Dermatological Cond
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Drugs for other Dermatological Cond
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Drugs forLeprosy Rifampicin I: Lepr
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SECTION 12 DIAGNOSTIC AGENTS RADIOC
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Diagnostic agents A/E: Nausea, vomi
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Diagnostic agents reactions;hyperth
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SECTION 13 DISINFECTANTS AND ANTISE
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Disinfectants And Antiseptics ADMIN
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Disinfectants And Antiseptics Gluta
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Loop Diuretics P/A: Dose: Tablets 4
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Osmotic Diuretics D/I: Increases di
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SECTION 15 DRUGS USED IN DENTISTRY
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Drugs for Dentistry STEROIDS Triamc
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Drugs for ENT A/E: P/A: Candidiasis
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Drugs for ENT C/I : Hypersensitivit
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Ulcer Healing Drugs mecamylamine,ps
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Antispasmodics syndrome. Lansoprazo
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Antiemetics And Prokinetics radioth
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Anti Diarrhoeals gastroenteritis an
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Laxatives osteomalacia; complete de
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Drugs Used In Inflammatory Bowel Di
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Drugs Used In Gall Stones and Heamo
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SECTION 18 HORMONES AND OTHER ENDOC
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Adrenal Hormones And Synthetic Subs
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Adrenal Hormones And Synthetic Subs
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Antiandrogens Ointment 2 % w/w, 5 %
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Oestrogens And AntiOestrogens A/E:
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Progestins And Antiprogestins A/E :
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Insulin and Other Anidiabetic Drugs
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Insulin and Other Anidiabetic Drugs
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Thyroid and Anit Thyroid Drugs Cost
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Vitamin D Derivatives orally. Anxie
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Bisphosphonates Dose: Hypercalcemia
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Sera and immunoglobulins Hypersensi
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Vaccines Hepatitis B Immunoglobulin
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Vaccines Dose: Primary immunization
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Vaccines Child:1-15 years: IM, 0.5
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SECTION 20 IMMUNOSUPPRESSANT DRUGS
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Cytotoxic drugs A/E: Hypersensitivi
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Glucocorticoids I : C/I: P/C : A/E:
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Drug treatment of Urolithiasis I: I
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Benign prostatic hypertrophy Terazo
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Urinary Frequency and Enuresis Dose
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Drugs For Impotence A/E : Penile pa
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SECTION 22 MUSCLE RELAXANTS AND ANT
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Central Muscle Relaxants Botulinum
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Peripheral Muscle Relaxant D/I: Sam
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Anticholinesterases C/I: P/C: A/E:
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SECTION 23 OPHTHALMOLOGICAL PREPARA
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Corticosteroids used in Ophthalmolo
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Drug used for Glaucoma Antagonists
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Nutritional Disorders affecting the
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Drugs and Pregnancy Drugs to be avo
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Oxytocics The drip is started with
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Drugs for Induction of Labour PROST
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Drugs for Vaginitis 2. Oral : fluco
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Drugs for Dysfunctional Uterine Ble
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SECTION 25 PSYCHOTHERAPEUTIC DRUGS
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Antipsychotic Drugs Fluphenazine Hy
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Antipsychotic Drugs start initially
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Antipsychotic Drugs dose upto 200 m
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Antipsychotic Drugs Discontinue, if
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Antidepressants reduction of effect
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Antidepressants Doxepin I: Depressi
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Antidepressants Citalopram I, A/E a
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Antidepressants P/C: Renal or hepat
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Anxiolytics C/I: P/C: A/E: P/A: Dos
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Anxiolytics Adjunct in acute alcoho
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Drugs used in substance dependence
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SECTION 26 PAEDIATRIC DRUGS AND NUT
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Paediatric drugs 333
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Paediatric drugs Medication >50 % 1
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Paediatric drugs Dicyclomine Hydroc
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Paediatric drugs Terbutaline A/E: T
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Paediatric drugs Amiodarone: A/E :
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Paediatric drugs STATINS Atorvastat
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Paediatric drugs Fosphenytoin P/A:
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Paediatric Nutrition NUTRITION Reco
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Paediatric Nutrition Daily requirem
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Paediatric Nutrition 6. Vitamin K M
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Paediatric Nutrition Calcium Calciu
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Paediatric Nutrition Combination wi
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Drugs for Respiratory Diseases P/A:
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Drugs for Upper Respiratory tract i
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Drugs for Tuberculosis headache, at
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Drugs for Tuberculosis several mont
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Drugs for Asthma and COPD may produ
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Drugs for Tuberculosis Dose: Etophy
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Drugs for Tuberculosis P/A: Inhaler
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Drugs for Tuberculosis Drugs availa
Page 399 and 400: Cough Suppressants and Mucolytics I
Page 401 and 402: SECTION 28 SOLUTIONS CORRECTING WAT
Page 403 and 404: Oral rehydration Salts I : P/C: A/E
Page 405 and 406: Parental Solutions mmol/litre in 24
Page 407 and 408: Parental Solutions oedema or water
Page 409 and 410: Parental Solutions I: pre- and peri
Page 411 and 412: Total Parental Nutritions solution
Page 413 and 414: Intravenous access device used for
Page 415 and 416: Intravenous access device advanced
Page 417 and 418: Forms of Intravenous Therapy Effect
Page 419 and 420: Forms of Intravenous Therapy Fluid
Page 421 and 422: Vitamins and Minerals severe, iodiz
Page 423 and 424: Vitamins and Minerals be precipitat
Page 425 and 426: Vitamins and Minerals CHILD 75-125
Page 427 and 428: Vitamins and Minerals INFANT under
Page 429 and 430: PART II GUIDELINES FOR FIRST LINE M
Page 431 and 432: General Topics pulmonary emergencie
Page 433 and 434: General Topics If the patient is sh
Page 435 and 436: General Topics DECONTAMINATION The
Page 437 and 438: General Topics should be monitored.
Page 439 and 440: General Topics 13. Benzodiazepines
Page 441 and 442: General Topics FIRST AID 1. Reassur
Page 443 and 444: General Topics When to repeat ASV A
Page 445 and 446: General Topics stings should be war
Page 447 and 448: Paediatrics Dose: 1 packet of ORS d
Page 449: Paediatrics 5. fatigue and exhausti
Page 453 and 454: Paediatrics neurological status. If
Page 455 and 456: CARDIOLOGY Evaluation of chest pain
Page 457 and 458: Cardiology ST segment elevation can
Page 459 and 460: Cardiology Contraindications for be
Page 461 and 462: Cardiology Cardiac arrest and its m
Page 463 and 464: Cardiology the procedure so that mo
Page 465 and 466: Cardiology Approach to treatment de
Page 467 and 468: Cardiology Adrenergic inhibitors La
Page 469 and 470: Respiratory System case crystalline
Page 471 and 472: Respiratory System 3. Acute Iaryngi
Page 473 and 474: Respiratory System PLEURAL EFFUSION
Page 475 and 476: Alimentary System comatose. Cardiac
Page 477 and 478: Alimentary System such as aluminium
Page 479 and 480: Endocrinology ‣ Tachycardia ‣ H
Page 481 and 482: Endocrinology Thyroid crisis can be
Page 483 and 484: NEUROLOGY COMA Coma is one of the m
Page 485 and 486: Neurology anticonvulsant action of
Page 487 and 488: OBSTETRICS AND GYNECOLOGY HYPEREMES
Page 489 and 490: Obstetrics and Gynecology Transfer
Page 491 and 492: Ophthalmology does not warrant any
Page 493 and 494: PART III A. LIST OF ESSENTIAL DRUGS
Page 495 and 496: Primary Care Hospitals 7. ANTIEPILE
Page 497 and 498: Secondary Care Hospitals 23.IMMUNOL
Page 499 and 500: Secondary Care Hospitals 44 TERBUTA
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Secondary Care Hospitals 90 GLYCERI
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Taluk Hospitals 140 INSULIN BOVINE,
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Taluk Hospitals 33 METRONIDAZOLE IN
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Taluk Hospitals 7. ANTIDOTES AND OT
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Taluk Hospitals 126 DIGOXIN TAB IP
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Taluk Hospitals 176 DEXTROSE INJ IP
Page 513 and 514:
Tertiary Hospitals 28.VITAMINS & MI
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Tertiary Hospitals 46 AZITHROMYCIN
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Tertiary Hospitals 7. ANTIDOTES AND
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Tertiary Hospitals 145 HEPARIN SODI
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Tertiary Hospitals 19. OPHTHALMIC D
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Tertiary Hospitals 249 HYDROGEN PER
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Tertiary Hospitals 303 FERROUS SULP
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Child Health 1. Progesterone only p
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Diarrhoea Control Programme end of
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National Immunization Schedule 5. N
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National TB Control Programme DOTS
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National Filaria Control Programme
Page 537 and 538:
APPENDIX 1 PREGNANCY During pregnan
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Alcuronium Amitriptyline Amoxyillin
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Didanosine Diethylcarbamazine Doxyc
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Magnesium sulfate Medroxyprogestero
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methaemoglobinaemia; fear of increa
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Table of medicines present in breas
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Gentamicin Hydrochlorothiazide Insu
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dose leaving the normal interval be
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Benzathine penicillin Severe Neurot
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elimination such as clearance and h
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Heparin Hydralazine Hydrochlorothia
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APPENDIX : 6 LIST OF EMERGENCY MEDI
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1. ANAESTHETICS 1.1. General anesth
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4.2. Specific Antisnake Venom U Inj
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Clarithromycin* S,T Capsules 500 mg
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6.4.2.3 Protease inhibitors Indinav
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Etoposide* T Capsules 100mg Injecti
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12. CARDIOVASCULAR MEDICINES 12.1.
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Provide Iodine U Solution or Ointme
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17.2 Antiemetics Domperidone U Tabl
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Norethisterone U Tablets 5 mg 18.8
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Methyl Ergometrine U Tablets 0.125m
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Calcium salts U Tablets 250,500 mg
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Drugs Minimum Maximum Rifampicin 45
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54. Fixed dose combination of Analg
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APPENDIX 8 ADVERSE DRUG EVENT REPOR
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Amiloride .........................
Page 591 and 592:
Bromhexine ........................
Page 593 and 594:
Conjugated oestrogen ..............
Page 595 and 596:
Esmolol ...........................
Page 597 and 598:
Hydrochlorothiazide ...............
Page 599 and 600:
Loxapine ..........................
Page 601 and 602:
Nitrous Oxide .....................
Page 603 and 604:
Povidone iodine ...................
Page 605 and 606:
Sodium Thiosulphate ...............
Page 607:
Vaccines ..........................
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