Kerala State Drug Formulary.pdf

methaemoglobinaemia; fear of increased
risk of kernicterus in neonates
Suxamethonium
Mildly prolonged maternal paralysis may
occur
Tamoxifen Avoid—possible effects on fetal
development;
Testosterone
All trimesters: Masculinization of female
fetus
Tetracycline
Thiopental
Trimethoprim
Vaccine, Influenza
Vaccine, Measles
Vaccine, MMR
Vaccine, Rubella
Vaccine, Varicella
Verapamil
Warfarin
Zidovudine
All anti malignant drugs
First trimester: Effects on skeletal
development Second, third trimesters:
Dental discoloration
Third trimester: Depresses neonatal
respiration; dose should not exceed 250
mg
First trimester: Teratogenic risk (folate
antagonist)
Not known to be harmful
First trimester: Theoretical risk of
congenital malformations
Avoid; pregnancy should be avoided for l
month after immunization
Avoid; pregnancy should be avoided lor l
month after immunization
Avoid; pregnancy should be avoided for
3 months after immunization
May reduce uterine blood flow with fetal
hypoxia; may inhibit labour
All trimesters: Congenital malformations;
fetal and neonatal haemorrhage
Avoid if possible in first trimester; benefit
of treatment considered to outweigh risk
in second and third trimesters
Avoid - teratogenic
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