Kerala State Drug Formulary.pdf

Antiinfective Drugs
abnormalities in haematological parameters, positive
Coomb’s test, seizures, taste disturbances, allergic
reactions;myoclonic activity, convulsions, confusion and
mental disturbances reported; slight increase in liver
enzymes and bilirubin reported, rarely hepatitis;
increase in serum creatinine and blood urea.
P/A : Injection, 250mg/vial, 500mg/vial as imipenem (powder
for reconstitution)
Dose : I.M(as imipenem) 500-750mg, every l2 hours in mild
to moderate infections. I.V(as imipenem) 1-2g daily in
3-4 divided doses, max. 4g or 50mg/kg daily
Meropenem:
I: Aerobic and Anaerobic gram + and gram – infections
C/I: Hypersensitivity.
P/C: History of hypersensitivity to other beta-lactam
antibiotics, infants