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7 Potency of Plant Products<strong>in</strong> Control of Virus Diseasesof PlantsH.N. VERMA 1 AND V.K. BARANWAL 21 Jaipur National University, Jaipur, India; 2 Advanced Centre of PlantVirology, New Delhi, IndiaAbstractThe exploitation of the <strong>in</strong>herent resistance phenomenon and manipulation of <strong>in</strong>ducibledefence <strong>in</strong> <strong>plant</strong>s is currently receiv<strong>in</strong>g much attention by researchers to control virus<strong>in</strong>fection. Recent advances <strong>in</strong> the molecular biology of resistance to virus <strong>in</strong>fectionhave presented new approaches for mak<strong>in</strong>g susceptible crops resistant aga<strong>in</strong>st virus<strong>in</strong>fection. These approaches <strong>in</strong>clude pathogen-derived resistance to viruses (coatprote<strong>in</strong>-mediatedresistance, movement-prote<strong>in</strong>-mediated resistance, replicase- andprotease-mediated resistance) and virus resistance through transgenic expression ofantiviral prote<strong>in</strong>s of non-viral orig<strong>in</strong>. Endogenously occurr<strong>in</strong>g substances <strong>in</strong> a fewhigher <strong>plant</strong>s have also been reported to <strong>in</strong>duce systemic resistance <strong>in</strong> susceptiblehosts aga<strong>in</strong>st virus <strong>in</strong>fections. Ribosome-<strong>in</strong>activat<strong>in</strong>g prote<strong>in</strong>s (RIPs) may also play animportant role <strong>in</strong> the prevention of virus <strong>in</strong>fection.7.1 IntroductionViruses prove to be a menace to humans and the environment because oftheir disease-caus<strong>in</strong>g nature. They harm crops and cause economic losses.The recent outbreak of cotton leaf curl virus disease <strong>in</strong> cotton <strong>in</strong> the northerncotton-grow<strong>in</strong>g region of India has led to a huge yield loss of cotton fibre.Approximately 12,000 hectares of cotton were affected by leaf curl virusdisease dur<strong>in</strong>g 1996 <strong>in</strong> Rajasthan alone. An annual loss of US$300 million iscaused by mungbean yellow mosaic virus (MYMV) by reduc<strong>in</strong>g the yield ofblack gram, mungbean and soyabean (Varma et al., 1992). The worldwidelosses caused by viral diseases are estimated at about US$60 billionper year.To reduce losses, scientists have explored several strategies to controlvirus <strong>in</strong>fection. However, it is the exploitation of the <strong>in</strong>herent resistancephenomenon and manipulation of <strong>in</strong>ducible defence <strong>in</strong> <strong>plant</strong>s that arereceiv<strong>in</strong>g much attention from researchers. The common approach for© CAB International 2011. Natural Products <strong>in</strong> Plant Pest Management(ed. N.K. Dubey) 149

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