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natural-products-in-plant-pest-management

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Global Scenario and Natural Products 5(a) (b) (c)CHH 3C CH 2HOHOOHOOHOOHHONOHNNCH 3OCH 3HOHOOHOOOHOHFig. 1.1. (a) Rotenone (b) Nicot<strong>in</strong>e (c) Ryanod<strong>in</strong>e.Used widely until the 1940s, such botanical <strong>pest</strong>icides were partly displacedby synthetic <strong>pest</strong>icides that at the time seemed easier to handle andlonger last<strong>in</strong>g. With the knowledge of the adverse effects of synthetic <strong>pest</strong>icides,worldwide attention is currently be<strong>in</strong>g given to shift<strong>in</strong>g to nonsyntheticsafer <strong>pest</strong>icides. There is renewed <strong>in</strong>terest <strong>in</strong> the application ofbotanical <strong>pest</strong>icides for crop protection, and scientists are now experiment<strong>in</strong>gand work<strong>in</strong>g to protect crops from <strong>pest</strong> <strong>in</strong>festations us<strong>in</strong>g <strong>in</strong>digenous<strong>plant</strong> materials (Roy et al., 2005).1.4 Plant Products <strong>in</strong> Current Worldwide Use as PesticidesThe <strong>plant</strong> k<strong>in</strong>gdom is recognized as the most efficient producer of chemicalcompounds, synthesiz<strong>in</strong>g many <strong>products</strong> that are used <strong>in</strong> defence aga<strong>in</strong>stdifferent <strong>pest</strong>s (Prakash and Rao, 1986; 1997; Charleston et al., 2004; Ismanand Akhtar, 2007). Higher <strong>plant</strong>s conta<strong>in</strong> a wide spectrum of secondarymetabolites such as phenolics, flavonoids, qu<strong>in</strong>ones, tann<strong>in</strong>s, essential oils,alkaloids, sapon<strong>in</strong>s and sterols. Tens of thousands of secondary <strong>products</strong> of<strong>plant</strong>s have been identified and there are estimates that hundreds of thousandsof such compounds exist. These secondary compounds represent alarge reservoir of chemical structures with biological activity. Therefore,higher <strong>plant</strong>s can be exploited for the discovery of new bioactive <strong>products</strong>that could serve as lead compounds <strong>in</strong> <strong>pest</strong>icide development because oftheir novel modes-of-action (Philogene et al., 2005). The ra<strong>in</strong>forest <strong>plant</strong>sare particularly thought to have developed a complete array of defenceprovid<strong>in</strong>gchemicals. This resource is largely untapped for use as <strong>pest</strong>icides(Tripathi et al., 2004).Extracts prepared from different <strong>plant</strong>s have been reported from time totime to have a variety of properties <strong>in</strong>clud<strong>in</strong>g <strong>in</strong>secticidal activity, repellenceto <strong>pest</strong>s, antifeedant effects, <strong>in</strong>sect growth regulation, toxicity to nematodes,mites and other agricultural <strong>pest</strong>s, and also antifungal, antiviral andantibacterial properties aga<strong>in</strong>st pathogens (Prakash and Rao, 1986, 1997).

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