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ISQ User Guide - Write Frame of Mind

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Tuning the <strong>ISQ</strong><br />

Tuning will improve the performance <strong>of</strong> your <strong>ISQ</strong>. For optimum stability, you should start<br />

tuning after the lights on the front <strong>of</strong> the instrument are a solid green. These lights indicate<br />

that the instrument has reached vacuum and that it is at the last set temperature. If the system<br />

has been powered <strong>of</strong>f for a period <strong>of</strong> time (a cold system), it takes longer (up to 4 hours) for<br />

the <strong>ISQ</strong> components to reach vacuum and temperature. If you did not vent the <strong>ISQ</strong> (system is<br />

hot), it takes approximately 30 minutes for the <strong>ISQ</strong> components to reach vacuum and<br />

temperature.<br />

IMPORTANT Be sure to give the <strong>ISQ</strong> enough time to stabilize. Otherwise, you may see<br />

mass drift, mass spectral changes, or changes in the fragmentation <strong>of</strong> your data.<br />

Thermo Scientific <strong>ISQ</strong> <strong>User</strong> <strong>Guide</strong> 17<br />

3

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