ISQ User Guide - Write Frame of Mind

Preface
About Your System
This guide contains detailed information about how to use the Thermo Scientific ISQ single
quadrupole GC-MS system. The ISQ is designed to stay cleaner, longer, to maximize your
instrument’s uptime and improve your lab’s productivity. The need to break vacuum, cool off
your system, and spend hours cleaning, reassembling, and restoring the system is gone. The
heated ion volume, lens stack, and ion optics path in the ISQ ensure that the system stays
cleaner longer, but when the system no longer meets your analytical needs, restoring
performance is quick and easy. The ExtractaBrite source incorporates a cartridge that contains
the repeller, source lenses, and RF lens, all of which can be removed from the instrument
while still under vacuum. What once took hours, or even an entire day, is now accomplished
in minutes.
Thermo Fisher Scientific systems provide the highest caliber gas chromatography/mass
spectrometry (GC/MS) instrumentation available on today’s market.
GC/MS represents a combination of two powerful analytical techniques: GC, which acts as a
separation technique and MS, which acts as a detection technique. Complex mixtures of
individual compounds can be injected into the GC, either manually or through the use of an
optional autosampler, and then separated for presentation to the MS. The MS will then
generate a mass spectrum of the GC eluent and its components, which can be used for
qualitative identification, as well as accurate and precise quantification of the individual
compounds present in the sample.
WARNING Thermo Fisher Scientific systems operate safely and reliably under carefully
controlled environmental conditions. If the equipment is used in manner not specified by
the manufacturer, the protections provided by the equipment may be impaired. If you
maintain a system outside the specifications listed in this guide, failures of many types,
including personal injury or death, may occur. The repair of instrument failures caused by
operation in a manner not specified by the manufacturer is specifically excluded from the
Standard Warranty and service contract coverage.
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