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Science of Water : Concepts and Applications

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290 The <strong>Science</strong> <strong>of</strong> <strong>Water</strong>: <strong>Concepts</strong> <strong>and</strong> <strong>Applications</strong><br />

√ Note: You don’t need to be a rocket scientist to fi gure out just how deadly cholera was during<br />

the London cholera outbreak <strong>of</strong> 1854. Comparing the state <strong>of</strong> “medicine” at that time to ours<br />

is like comparing the speed potential <strong>of</strong> a horse <strong>and</strong> buggy to a state-<strong>of</strong>-the-art NASCAR race<br />

car today. Simply stated, cholera was the classic epidemic disease <strong>of</strong> the nineteenth century, as<br />

the plague had been for the fourteenth. Its defeat was a refl ection <strong>of</strong> both common sense <strong>and</strong><br />

<strong>of</strong> progress in medical knowledge—<strong>and</strong> <strong>of</strong> the enduring changes in European <strong>and</strong> American<br />

social thought.<br />

How does a person contract cholera? Good question. Again, we refer to the CDC for our answer.<br />

A person may contract cholera (even today) by drinking water or eating food contaminated with the<br />

cholera bacterium. In an epidemic, the source <strong>of</strong> the contamination is usually feces <strong>of</strong> an infected<br />

person. The disease can spread rapidly in areas with inadequate treatment <strong>of</strong> sewage <strong>and</strong> drinking<br />

water. Disaster areas <strong>of</strong>ten pose special risks. The aftermath <strong>of</strong> Hurricane Katrina, for example, in<br />

New Orleans caused concern for a potential cholera problem.<br />

Cholera bacterium also lives in brackish river <strong>and</strong> coastal waters. Shellfi sh eaten raw have been<br />

a source <strong>of</strong> cholera, <strong>and</strong> a few people in the United States have contracted cholera after eating raw<br />

shellfi sh from the Gulf <strong>of</strong> Mexico. The disease is not likely to spread directly from one person<br />

to another; therefore, casual contact with an infected person is not a risk for transmission <strong>of</strong> the<br />

disease.<br />

Flashback to 1854 London<br />

The information provided in the preceding section was updated <strong>and</strong> provided by the CDC in 1996.<br />

Basically, for our purposes, the CDC confi rms the fact that cholera is a waterborne disease. Today,<br />

we know quite a lot about cholera <strong>and</strong> its transmission, how to prevent infection, <strong>and</strong> how to treat it.<br />

But what did they know about cholera in the 1850s? Not much—however, one thing is certain: They<br />

knew cholera was a deadly killer. That was just about all they knew—until Dr. John Snow proved<br />

his theory. Recall that Snow theorized that cholera is a contagious disease caused by a poison that<br />

reproduces in the human body <strong>and</strong> is found in the vomitus <strong>and</strong> stools <strong>of</strong> cholera victims. He also<br />

believed that the main means <strong>of</strong> transmission was water contaminated with this poison.<br />

Dr. Snow’s theory was correct, <strong>of</strong> course, as we know today. The question is, how did he prove<br />

his theory correct? The answer to this provides us with an account <strong>of</strong> one <strong>of</strong> the all-time legendary<br />

quests for answers in epidemiological research—<strong>and</strong> an interesting story.<br />

Dr. Snow proved his theory in 1854, during yet another severe cholera epidemic in London.<br />

Although ignorant <strong>of</strong> the concept <strong>of</strong> bacteria carried in water, Snow traced an outbreak <strong>of</strong> cholera to<br />

a water pump located at an intersection <strong>of</strong> Cambridge <strong>and</strong> Broad Street (London).<br />

How did he isolate this source to this particular pump? He accomplished this by mapping the<br />

location <strong>of</strong> deaths from cholera. His map indicated that the majority <strong>of</strong> the deaths occurred within<br />

250 yards <strong>of</strong> that water pump. The water pump was used regularly by most <strong>of</strong> the area residents.<br />

Those who did not use the pump remained healthy. Suspecting the Broad Street pump as the plague’s<br />

source, Snow had the water pump h<strong>and</strong>le removed <strong>and</strong> ended the cholera epidemic.<br />

Sounds like a rather simple solution, doesn’t it? For us, it is simple, but remember, in that<br />

era, aspirin had not yet been formulated—to say nothing <strong>of</strong> other medical miracles we take for<br />

granted—for example, antibiotics. Dr. John Snow, by the methodical process <strong>of</strong> elimination <strong>and</strong><br />

linkage (Sherlock Holmes would have been impressed—<strong>and</strong> he was), proved his point, his theory.<br />

Specifi cally, through painstaking documentation <strong>of</strong> cholera cases <strong>and</strong> correlation <strong>of</strong> the comparative<br />

incidence <strong>of</strong> cholera among subscribers to the city’s two water companies, Snow showed that<br />

cholera occurred much more frequently in customers <strong>of</strong> the water company that drew its water from<br />

the lower Thames, where the river had become contaminated with London sewage. The other company<br />

obtained water from the upper Thames. Snow tracked <strong>and</strong> pinpointed the Broad Street pump’s<br />

water source. You guessed it: the contaminated lower Thames, <strong>of</strong> course.

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