1478 JOURNAL OF COMPUTERS, VOL. 8, NO. 6, JUNE 2013 Figure 7. The circle of Willis pulse wave with the cerebral <strong>in</strong>farction. We can see the pulse wave of the cerebral <strong>in</strong>farction from the simulation figure 6, the K value is 0.495, and is close to the cl<strong>in</strong>ical test of cerebral <strong>in</strong>farction <strong>in</strong> Table II, K = 0.55 ± 0.12, from the chang<strong>in</strong>g trend of the K value, this result matches with the actual cl<strong>in</strong>ical detection basically. V. CONCLUSION In summary, the pulse waveforms extracted the K value by averag<strong>in</strong>g computation and the wave area, although it does not fully reflect subtle changes <strong>in</strong> the pulse curve that conta<strong>in</strong>s all the local physiological and pathological significance, but it represents some important physiological parameters <strong>in</strong> the human blood circulatory system, such as peripheral vascular resistance, blood viscosity and so on. Consider<strong>in</strong>g the characteristic <strong>in</strong>formation to reduce only one characteristic quantity K, it is easy to remember, a clear physiological significance, and changes very regular, can be easily accepted by cl<strong>in</strong>icians, so it can be used as important cardiovascular physiological parameters of the cl<strong>in</strong>ical exam<strong>in</strong>ation. In the averag<strong>in</strong>g comput<strong>in</strong>g pulse wave process, the network only needs to know the relevant basic physiological parameters of blood vessel branch, and calculat<strong>in</strong>g the pulse wave and the K value is more high precision than pulse wave detector. The stability test<strong>in</strong>g results do not affect with the emotional fluctuates <strong>in</strong> the waveform, the different K values corresponds to different pathological conditions, so that it can provide an nondestructive test<strong>in</strong>g mathematical calculation and analysis methods for the cl<strong>in</strong>ical parameters of blood circulation. ACKNOWLEDGMENT This work is supported by NSF 60970105; education department S&T plan J08LJ70 and NSF of Shandong Prov<strong>in</strong>ce ZR2010FL015 and ZR2010FL021; MOHURD and Shandong Development science and technology project 2010-K9-26 and 2011YK05. REFERENCES [1] D<strong>in</strong>g Guang-hong, Yao Wei,Wang Yan-bo, “A Hemodynmic Model and A Mathematical Method to calculate the Dynamics <strong>in</strong>dex for Cerebral Circulation”, Journal of Hydrodynamics, Ser. B, vol. 9, no.4, pp.71-78, 1997. [2] Satish Chandra , Rajesh Bhat , Har<strong>in</strong>der S<strong>in</strong>gh , D.S.Chauhan, "Detection of Bra<strong>in</strong> Tumors from MRI us<strong>in</strong>g Gaussian RBF kernel based Support Vector Mach<strong>in</strong>e", © 2013 ACADEMY PUBLISHER
JOURNAL OF COMPUTERS, VOL. 8, NO. 6, JUNE 2013 1479 IJACT: International Journal of Advancements <strong>in</strong> Comput<strong>in</strong>g Technology, vol. 1, no. 1, pp. 46-51, 2009. [3] Hui Liu, Guochao Sun, " A New Method of Medical Image Retrieval for Computer-Aided Diagnosis", Journal of Software, v 7, n 6, p 1289-1295, 2012. [4] Berend Hillen, Hendrik W. Hoogstraten and Lourens Post, “A mathematical model of the flow <strong>in</strong> the circle of Willis”, Journal of Biomechanics, Elsevier, vol. 19, no.3, pp. 187- 194, 1986. [5] Berend Hillen, Bart A.H. Dr<strong>in</strong>kenburg, Hendrik W. Hoogstraten and Lourens Post, "Analysis of flow and vascular resistance <strong>in</strong> a model of the cricle of Willis", Journal of Biomechanics, Elsevier, vol. 21, no.10, pp. 807- 814, 1988. [6] Wang, Xiaoyong, Fang, Yuefeng, "Study on remote aided diagnosis system of mental health base on export knowledge base", Journal of Software, v 6, n 5, p 834-841, 2011. [7] Mauro Urs<strong>in</strong>o, Massimo Giannessi, "A Model of Cerebrovascular Reactivity Includ<strong>in</strong>g the Circle of Willis and Cortical Anastomoses", Annals of Biomedical Eng<strong>in</strong>eer<strong>in</strong>g, vol. 38, no.3, pp.955-974, 2010. [8] Liang F, Fukasaku K, Liu H, et al., "A computational model study of the <strong>in</strong>fluence of the anatomy of the circle of willis on cerebral hyperperfusion follow<strong>in</strong>g carotid artery surgery", Biomedical Eng<strong>in</strong>eer<strong>in</strong>g Onl<strong>in</strong>e, pp. 84.2010. [9] Devault K, Gremaud PA, Novak V, et al., Blood Flow <strong>in</strong> the circle of willis: Model<strong>in</strong>g and Calibration, Multiscale Model Simulation, vol. 7, no.2, p888-909, 2008. [10] Seol HJ, Sh<strong>in</strong> DC, Kim YS, et al., Computational analysis of hemodynamics us<strong>in</strong>g a two-dimensional model <strong>in</strong> moyamoya disease, Journal Neurosurg Pediatr, vol. 5, no.3, p297-301, 2010. [11] Luo zhichang, Zhang Song, Yang Wenm<strong>in</strong>g, "A research on characteristic <strong>in</strong>formation of pulse wave", Journal of Beij<strong>in</strong>g polytechnic university, vol.22, no.1, pp.71-79, 1996. [12] Li Yang, J<strong>in</strong>xue Sui, Yunan Hu, X<strong>in</strong>li Zhang, Yan J<strong>in</strong>, "Cerebral Circulation Nonl<strong>in</strong>ear Model<strong>in</strong>g and Vertebral Artery Stenosis Pathological Simulation", JCIT: Journal of Convergence Information Technology, Vol. 6, No. 11, pp. 361 ~ 370, 2011. [13] J<strong>in</strong>xue Sui, Yun'an Hu, Li Yang, Zhen Hua, "A Hemodynamics M<strong>in</strong>imal Model for the Cerebral Circulation of Willis Based on Graph Theory", The 2nd International Conference on Bio<strong>in</strong>formatics and Biomedical Eng<strong>in</strong>eer<strong>in</strong>g, pp.1796-1799, 2008. [14] Yun'an Hu, J<strong>in</strong>xue Sui, Li Yang, Zhen Hua, "A Nonl<strong>in</strong>ear Model for the Circle of Willis Based on Hemodynamics”, The 3rd International Conference on Bio<strong>in</strong>formatics and Biomedical Eng<strong>in</strong>eer<strong>in</strong>g, pp.1-4, 2009. [15] Olga I. Koroleva, Miroslav Krstic, “Averag<strong>in</strong>g analysis of periodically forced Fluid flow networks”, Automatica, Elsevier, vol. 41, no.1, pp.129-135, 2005. [16] Yunan Hu, Olga I. Koroleva, Miroslav Krstic, Nonl<strong>in</strong>ear Control of M<strong>in</strong>e Ventilation Networks, Systems & Control Letters, 2003,49: 239-254. [17] Sui, J<strong>in</strong>xue, Yang, Li, Hu, Yunan, Zhu, Zhil<strong>in</strong>, "Cerebral circulation network model<strong>in</strong>g and averag<strong>in</strong>g pathological analysis", Applied Mechanics and Materials, vol. 40-41, pp.133-139, 2011. [18] Li Yang, J<strong>in</strong>xue Sui, Yunan Hu, X<strong>in</strong>li Zhang, Yan J<strong>in</strong>, "Cerebral Circulation Averag<strong>in</strong>g Computation and Pathological Analysis", IJACT: International Journal of Advancements <strong>in</strong> Comput<strong>in</strong>g Technology, Vol. 3, No. 11, pp. 88 ~ 95, 2011. [19] H.K. Khalil, Nonl<strong>in</strong>ear Systems, 3rd ed., Prentice Hall, 2002. [20] Han Zengj<strong>in</strong>, Adaptive control, Beij<strong>in</strong>g: Ts<strong>in</strong>ghua University Press, 1995: 171 -192. Li Yang received the B.S. degree <strong>in</strong> the applied mathematics from yantai university, Yantai <strong>in</strong> 2002 and the M.S. degree and <strong>in</strong> the operational research and cybernetics from Beij<strong>in</strong>g Jiaotong University, Ch<strong>in</strong>a, <strong>in</strong> 2005. Currently, she is an <strong>in</strong>structor with Shandong Institute of Bus<strong>in</strong>ess and Technology and doctoral student with Naval Aeronautical Eng<strong>in</strong>eer<strong>in</strong>g University, Ch<strong>in</strong>a. His research <strong>in</strong>terests are <strong>in</strong>telligent control, fluid network control. J<strong>in</strong>xue Sui, associate professor, he received the M.S. degree <strong>in</strong> the control theory and control eng<strong>in</strong>eer<strong>in</strong>g from Northeast Dianli University, Jil<strong>in</strong>, Ch<strong>in</strong>a <strong>in</strong> 2005 and the Ph.D.~degree <strong>in</strong> the navigation, guidance and control from Naval Aeronautical Eng<strong>in</strong>eer<strong>in</strong>g University, Yantai, Ch<strong>in</strong>a <strong>in</strong> 2009. Currently, he is a <strong>in</strong>structor with Shandong Institute of Bus<strong>in</strong>ess and Technology, Ch<strong>in</strong>a. His research <strong>in</strong>terests are <strong>in</strong>telligent sensor, fluid network control and biological control now. © 2013 ACADEMY PUBLISHER
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Call for Papers and Special Issues
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(Contents Continued from Back Cover