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Key Session: What is Good Evidence in Wound Care and How do We Generate it?<br />
159<br />
Free Paper Session: Diabetic Foot II<br />
158<br />
Helping to raise the quality of research evidence in wound<br />
management: lessons we have learnt<br />
Treatment Results of Septic Complications and Mixed Forms of<br />
Neuropathic Diabetic Foot<br />
Patricia Price 1<br />
Tamara Tamm 1 , M.S. Popov 1 , O.V. Danilova 1 , A.V. Pasechnik 1<br />
1 Cardiff University (Cardiff, United Kingdom).<br />
1 Ukrainian Wound Treatment Organisation (Ukraine).<br />
In 2010 the <strong>EWMA</strong> Patient Outcome Group (POG) published recommendations to<br />
improve the quality of evidence in wound management (www.ewma.org/english/<br />
publications/ewma-pog- evidence-doc.html). As a companion piece of work, the <strong>EWMA</strong><br />
POG is working to provide a user-friendly document to assist those new to (or<br />
inexperienced in) research in starting on the path to plan, conduct, interpret and<br />
disseminate findings from a study that will improve our understanding of clinical wound<br />
healing and raise the evidence level of the work undertaken in this important area. The<br />
documents will relate to venous leg ulcers, in the first instance. The target audience for<br />
this publication is hospital and community clinicians/researchers working collaboratively<br />
with other professions or industry; the text will take the format of a ‘step by step’<br />
instruction manual to highlight activities to consider and outline frequent mistakes that<br />
many of us have made along the way – with the aim of helping novice researchers avoid<br />
making them and improve the quality of studies that are undertaken. The emphasis will<br />
focus on Randomised Controlled Trials (RCTs) and Cohort Studies that are prospective<br />
(i.e., retrospective studies are not included): see Nice/UK: Guideline Manual 2009,<br />
Appendix M for an outline of different study designs (www.nice.org.uk/guidelinesmanual.<br />
As a European association, the focus will be on European regulations and directives.<br />
Relevance: In contrast to medicamentous treatment, surgery problem of foot destructive<br />
processes is not fixed, as connected with lack of consensus among surgeons as to<br />
surgery choice for such patients, who do not consider the form of foot lesions.<br />
Target: To improve patients treatment with purulent complications of Diabetic Foot<br />
Syndrome (DFS) results by increasing number of patients with preserved leg support<br />
function.<br />
Materials and Methods: Where analyzed results of surgical treatment of 379 patients<br />
with purulent DFS complications: 55 (14.5%) had ischemic form, 120 (31.7%) had<br />
neuropathic and 204 (53.8%) – mixed. Volume of observation included clinical<br />
examination, laboratory and instrumental methods.<br />
Results: It was found that neuropathic form primarily affects bone and joint structure.<br />
Suppurative arthritis and osteomyelitis were diagnosed in 294 (93.4%) patients with<br />
neuropathic and mixed forms. Separate injury of interphalangeal and<br />
metatarsophalangeal joints was performed resection of latter. Prevention of vascular<br />
lesions compression after joints resection was performed by orthopedic correction. It<br />
was found that around resected area formed pseudo articularis, which gives sufficient<br />
support and protection to vascular structures. It was done 34 (70.1%) arthrotomies and<br />
removals of bone structures. Were performed 111 (93%) closings of wounds defects with<br />
free splits or skin grafts. Foot support function was stored in 341 (93%) patients.<br />
Conclusions:<br />
1. Neuropathic and mixed forms of DFS with suppurative processes, often affect foot<br />
bone and joint structure.<br />
2. Foot surgery has to help to maintain support, which is achieved by surgery and<br />
orthopedic correction.<br />
KEY SESSION: WHAT IS GOOD EVIDENCE IN WOUND CARE AND HOW DO WE GENERATE IT?<br />
<strong>EWMA</strong> <strong>2013</strong><br />
COPENHAGEN<br />
15-17 May · <strong>2013</strong><br />
Danish Wound<br />
Healing Society<br />
99