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E-POSTER: CASE STUDY<br />

E-Poster: Case Study<br />

EP 554<br />

Topical ozone and chronic wounds: Improper use of therapeutic<br />

tools may delay wound healing<br />

Gunalp Uzun 1 , Mesut Mutluoglu 1 , Ercan Karabacak 1 , Huseyin Karagoz 1 , Hakan Ay 1<br />

1 GATA Haydarpasa Teaching Hospital Department of Underwater and Hyperbaric<br />

Medicine (İstanbul, Turkey)<br />

Aim: We present a patient with multiple non-healing lower extremity ulcers, and further<br />

discuss the inappropriate use of topical ozone therapy and the need for a<br />

comprehensive approach to wound management.<br />

Methods: A 40-year-old male patient applied to our hyperbaric and wound care center<br />

for multiple non-healing necrotic ulcers over his legs. Ulcers occurred around his ankles<br />

three months ago and spread proximally thereafter, despite topical antibiotic therapy and<br />

gauze dressings delivered at a local hospital. Sunk into despair, he was attracted from<br />

flyers advertising ozone therapy for chronic wounds. Thus, during the following four<br />

weeks, he received several topical ozone therapy sessions, which yielded no further<br />

significant signs of improvement. Eventually, he was suggested bilateral lower extremity<br />

amputation by a surgeon. On physical examination, he had multiple, necrotic, and<br />

infected deep ulcers in variable sizes reaching tendons in some areas.<br />

Results: We hospitalized the patient and undertook a holistic approach comprising<br />

aggressive anti-edema treatment, culture-driven intravenous antibiotic regimen, and<br />

comprehensive daily wound care, including debridement of necrotic tissues and<br />

management of exudates. All ulcers of both legs almost totally epithelized in 8 weeks.<br />

Conclusion: This case report highlights two major issues. First, the role of ozone<br />

therapy is still poorly defined in the management of foot ulcers and should be used with<br />

caution. Second, adjunctive therapies should only be applied when conventional<br />

treatments fail to heal the wound.<br />

EP 555<br />

E-Poster: Case Study<br />

Negatively Charged Microspheres- (NCM) Technology* for The<br />

Treatment of Post Aesthetic Surgery Complications<br />

Haik Josef 1 , Winkler Eyal 1 , Farber Nimrod 1 , Harats Moti 1 , Weissman Oren 1<br />

1 Sheba Medical Center, Department of plastic and Reconstructive Surgery and The Burn<br />

Unit (Ramat Gan, Israel).<br />

Background: Complications following aesthetic procedures such as lower T-junction<br />

wound dehiscence following breast reduction surgery, or flap necrosis following a facelift<br />

procedure are vexing and grievous complications both to the patient and the surgeon.<br />

Treatment modalities that can actively expedite wound healing rates in such cases are<br />

highly craved.<br />

Objectives: To assess wound healing and re-epithelialization rates of open wound<br />

treated by Negatively Charged Microspheres (NCM), following breast reduction and<br />

mastopexy wound dehiscence and flap necrosis following facelift procedures.<br />

Methods: Eight patients with wounds of the aforementioned types (5 breast reduction<br />

patients and 3 facelift patients) were treated with daily dressing with NCM soaked<br />

dressings. Wound closure rates were documented.<br />

Results: Treatment duration averaged 10 days in the facelift cases and 33 days for<br />

breast cases. Wounds showed both accelerated granulation tissue formation, and reepithelialization<br />

rates. Average wound epithelialization rate was 1.9 millimeters per day<br />

for breast cases and 1 millimeters per day for the facelift cases. In these cases, NCM<br />

treatment helped patients avoid additional surgery such as skin grafting. No<br />

complications or side effects were encountered.<br />

Conclusions: NCM treatment may offer a new and efficacious way to heal open wounds<br />

following aesthetic surgery complications. Furthermore, NCM may help avoid the need<br />

for additional reconstructive procedures which would have been quite a problem to the<br />

patient and the surgeon in the wake of aesthetic surgery complications. Further<br />

researches with larger patient numbers are warranted to corroborate these findings.<br />

<strong>EWMA</strong> <strong>2013</strong><br />

COPENHAGEN<br />

15-17 May · <strong>2013</strong><br />

Danish Wound<br />

Healing Society<br />

313

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