Here - EWMA 2013

POSTER PRESENTATIONS
P 250
First experience with topical wound oxygenation
in the healing of the diabetic foot (a pilot study)
Poster: Diabetic Foot
Vladimira Fejfarova 1 , Alexandra Jirkovska 1 , Michal Dubský 1 , Robert Bém 1 ,
Veronika Wosková 1
1 Diabetes Center, Institute for Clinical and Experimental Medicine (Prague, Czech
Republic).
The increase of pO2 in soft tissue could be achieved by revascularization, hyperbaric
oxygen therapy, but probably also by Topical wound oxygenation (TWO).
Aim: The aim of our study was to evaluate the potential effect of TWO on the state of
microcirculation and wound healing in patients with the DFU.
Methods: Into our study we included 6 patients with non-healing DFU despite complex
therapy (mean age 61.7±8.8 year, mean HbA1c 68±29 mmol/mol, mean wounds
duration 7.2±9.4 months). Each patient underwent 20 applications of TWO with 100%
humidified oxygen applied for 60 minutes at cyclic pressure of 5-50 mBars. The state of
microcirculation (rated by TcPO2), ulcer area and depth, type of wound tissue, PUSH
score were compared before and after TWO applications.
Results: After the TWO applications we found a significant increase of the TcPO2
values (37.8vs.47.2mmHg;p