Here - EWMA 2013

POSTER: CASE STUDY
Poster: Case Study
P 374
LONG TERM OUTCOMES OF A RANDOMIZED CONTROLLED TRIAL (RCT)
WITH NEGATIVELY CHARGED MICROSPHRES (NCM) TECHNOLOGY COMPARED
TO CONTROL
Hanna Kaufman 1 , Yaron Shoham 2 , Yuval Krieger 3 , Eldad Silberstein 3 ,
Alex Bogdanov-Berezovsky 3
1 Maccabie health care (Haifa, Israel);
2 Plastic Surgery Department, Soroka (Be’er Sheva, Israel);
3 Department, Soroka (Be’er Sheva, Israel).
Background: As life expectancy is increasing, non-healing wounds are a growing
clinical problem and major burden on health care systems. We report the results of
extended follow up of RCT study of treatment of recalcitrant ulcers with Negatively
Charged Microspheres (NCM1)-Technology or control treatment (saline).
Aim: To evaluate the long term safety and care-burden on patients and wound centers
following treatment with NCM1 technology or control.
Methods: Following completion of the controlled phase of 4 weeks active treatment,
patients were enrolled to extended follow-up study. During this period patients were
treated with standard practice (excluding NCM1 or saline). The follow up study included
assessments of wound status, incidence of adverse events and number of unplanned
hospitalizations.
Results: The incidence of adverse events reported in the NCM1 treated group was
lower than in the control group (14.8% vs 30% respectively). There were 50% more
wounds that remained closed in NCM1 group compared to the control arm. There was a
statistically significant reduction of NCM1 vs. control group in unplanned hospitalizations
and reduction in hospitalizations duration for target wound treatment (Mean 0.21
hospitalizations vs 1.43 respectively p= 0.0038; mean hospitalization days 2.53 vs 10.87
respectively p=0.0095).
Conclusions: NCM1 has shown following the active phase, long-term safety as well as
potentially reducing wound care and hospitalization burden. These outcomes may
suggest an important and cost/effective role for NCM1 in chronic wound care.
P 375
Role of Fasciaotomy in sever bilateral limbs infection:
– A case Report
Poster: Case Study
Awaji Alnaemi 1 , Saleem Syed 1
1 Ministry of health (Sabiya, Saudi Arabia).
Introduction: Infection is managed at different level, by combined or unique techniques
stretching from simple technique to amputation. However in certain situation,
controversies do exist, either due to medico-legel reason or because of differences in
basic understanding of pathology. In such situation any decision which is not adversely
affecting patient life and is in lower intensity of damage must be adopted. Our patient
reviewed by multidisciplinary team, with consensus of bilateral limb amputation. This was
not only a big psychological trauma, for the patient, but for the treating surgeon as well.
We put aside the opinion and did simple procedure for saving the limb and succeed.
Aim: How can we control sever soft tissue infection of both legs, other than amputation?
Methods: A 40 years old man, with known type-II diabetes Mellitus, admitted with sever
bilateral leg infection, septicemia, edema of both lower limbs and Diabetic keto-acidosis.
After resuscitation and complete workup and consultation, long releasing incisions were
made both anterior medial and posterior lateral side of the legs and feet as well. Several
repeated debridement and simple dressing with normal saline saved the limbs of patient.
Results: Patient got fantastic recovery, remained admit for 9 months, with added
mobility.
Conclusion/Discussion: Simple manure for deep soft tissue infection is always
overlooked. We recommend not hurrying for last resort that is amputation but consider
other options in the management of sever limbs infection as well.
EWMA 2013
COPENHAGEN
15-17 May · 2013
Danish Wound
Healing Society
217