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<strong>EWMA</strong> UCM LECTURE<br />

Key Session: E-health and the Future of Health Care Systems<br />

114<br />

Mobile wound healing center using telemedecine: Analysis of<br />

a database including 5795 patients and perspectives<br />

Luc Teot 1 , C. Trial 1 , J. Lan 1 , E. Riba 1 , S. Palmier 1<br />

1 University Hospital Montpellier (Montpellier, France).<br />

Introduction: The Home Hospital Wound Healing Network (HHWHN)is an expert<br />

network advising professionals GPs and nurses willing to get help in wound healing.<br />

These experts got a diploma in wound healing and are regularly trained and tutored. The<br />

Network uses since 10 years a system of teletransmission of clinical datas and pictures<br />

using computers and smartphones and rassembled on a special software. 5794 patients<br />

were inclused between January 2005 and October 2012 in this database. Functionalities<br />

of the database are detailed. Clinical efficacy and medicoeconomic results are analysed<br />

Results: Patients presenting polypathologies are the majority. Types of wounds<br />

analysed in the software are principally pressure ulcers (42%), leg ulcers (22%), diabetic<br />

foot ulcers (8%), postop wounds complications representing 12%. The mean length of<br />

study is 76 days. Economical markers show a reduce of costs in the management of<br />

wounds compared to previous hospitlaisations and transportations from home to wound<br />

healing centers.<br />

Conclusion: There is an increasing demand of assistance from professionals not<br />

specialised in wound healing facing complex wounds. The territorial coverage by a<br />

network of expert nurses and doctors may help to manage these pathologies which<br />

represent a high economical burden.<br />

115<br />

<strong>EWMA</strong> UCM Lecture<br />

The inflammatory response is regarded as the first of a number of<br />

overlapping processes that constitute wound healing<br />

Judit Daróczy 1<br />

1 Lymphoedema Rehabilitation Department (Hungary).<br />

Definition of the inflammation: Tissue injury causes the immediate onset of acute<br />

inflammation. Inflammatory cells secrete enzymes and various mediators that result in<br />

the classical hallmarks of inflammation: pain, redness, warmth, and swelling. It has been<br />

demonstrated that the inflammatory response during normal healing is characterized by<br />

spatially and temporally changing patterns of various leukocyte subsets.The<br />

development of effective inflammatory models that track the dynamic balance between<br />

changes in systemic neutrophil availability and their recruitment to the wound is<br />

important in identifying the mechanism that leads to normal or aberrant wound healing.<br />

In the early stages of wound healing, keratinocytes become activated and release<br />

inflammatory molecules such as IL-1 and IL-8, which are linked to innate immune<br />

responses and neutrophil recruitment. Fibrocytes are mesenchymal cells that arise from<br />

monocyte precursors. They are present in injured organs and have both the<br />

inflammatory features of macrophages and the tissue remodelling properties of<br />

fibroblasts. Chemokines (IL-8) stimulate angiogenesis and keratinocyte proliferation,<br />

they integrate the inflammatory events with the reparative processes.<br />

The role of inflammation in wound healing: The healing process of skin wounds is<br />

regulated by growth factors which stimulate proliferation of connective tissue cells,<br />

keratinocytes and their synthesis of extracellular matrixcomponents. Different leukocyte<br />

subtypes (neutrophils, macrophages, lymphocytes and mast cells) participate in wound<br />

healing not only as immunological effector cells but also as an important source of<br />

inflammatory and growth promoting cytokines and growth factors.<br />

<strong>EWMA</strong> <strong>2013</strong><br />

COPENHAGEN<br />

15-17 May · <strong>2013</strong><br />

Danish Wound<br />

Healing Society<br />

77

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