Here - EWMA 2013

E-POSTER: ACUTE WOUNDS
E-Poster: Acute Wounds
EP 430
NEGATIVE PRESSURE WOUND THERAPY: IS THE ROUTINELY APPLICATION
POSSIBLE IN BURNS?
Tommaso Anniboletti 1 , Marco Palombo 1 , Simone Moroni 1 , Paolo Palombo 1
1 Department of burn Centre and Plastica and Reconstructive Surgery, S. Eugenio
Hospital (Rome, Italy).
Aim: As an alternative to free tissue transfer, the dermal substitutes* were used in a one
stage procedure in combination with unmeshed split thickness skin grafts for
reconstruction. The aim of this study was to evaluate if the negative pressure therapy**
improves the skin graft take with or without the use of the dermal substitutes and the
wound closure in the acute burn patients.
Methods: This study was carried out on our burn center on 27 patients suffering from
burn or acute high-voltage injuries. All patients were evaluated concerning burn surface
area, burn degree, the application or not of the dermal substitute, a negative pressure
wound therapy treatment period of minimum 6 days and final outcome. The system**
was applied on 27 patients(21- 76 y.o.,). The dermal substitute*** was applied on 13
patients (32-76 y.o). The dermal regeneration template**** was applied on 7 patients
(6-76 y. o.).
Results: All patients were treated with burn wounds escharectomy and immediate
application of the negative pressure wound therapy with or without the use of the dermal
substitute. The negative pressure therapy was well tolerated by all patients. Final graft
take at 8 days was from 85 to 100% with an average of 91.3%.
Conclusions: Negative pressure wound therapy removes wound exudate and, at the
same time, allows an increased blood flow, a decreased edema, a decreased bacterial
counts and an earlier wound closure.
*Matriderm and Integra
**VAC
***Matriderm
****Integra
EP 431
E-Poster: Acute Wounds
OUR EXPERIENCE IN THE TREATMENT OF BURN PATIENT WITH HYALURONIC
ACID AND COLLAGENASES
Tommaso Anniboletti 1 , Marco Palombo 1 , Simone Moroni 1 , Paolo Palombo 1
1 Department of burn Centre and Plastica and Reconstructive Surgery, S. Eugenio
Hospital (Rome, Italy).
Aim: The goal, in the treatment of second-degree burn, is to achieve, in the shortest
time, the debridement of the wound to prepare the patients for skin grafting. The sodium
hyaluronate topical* is an ointment composed of hyaluronic acid, sodium salt 0,2% and
bacterial collagenases extracted from Vibrio Alginolyticus, a non-pathogenic bacterium.
The aim of this study is to evaluate the clinical efficacy of the sodium hyaluronate
topical* in deep second degree burns in long term.
Methods: In this prospective randomized study the sodium hyaluronate topical* was
used as wound dressing in 34 patients with deep second degree burns. The dressing
was applied and kept in situ covered by paraffin gauze. All patients were treated with
daily dressing.
Result: It showed a good improvement, visible already at day 5. Moreover, the medical
treatment promoted faster and complete wound healing in 20 out of 34 patients. Surgical
skin graft was needed in 14 patients.
Conclusion: Short terms topical application of the sodium hyaluronate topical* in
second degee burns promoted faster and complete wound healing thanks to its
formulation. Hyaluronic acid stimulates granulation tissue and protect the surrounding
normal tissue while the collagenases facilitate the enzymatic debridement. This study
encouraged the treatment with the sodium hyaluronate topical* for deep second degree
burns.
*Reference not available.
EWMA 2013
COPENHAGEN
15-17 May · 2013
Danish Wound
Healing Society
251