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Here - EWMA 2013

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ORAL PRESENTATIONS<br />

13<br />

SINGLE USE NEGATIVE PRESSURE WOUND THERAPY (SU-NPWT)<br />

FOR THE TREATMENT OF CHRONIC LOWER LEG WOUNDS<br />

Free Paper Session: Leg Ulcers I<br />

John Lantis 1 , Jamie Schwartz 1 , Ema Avdagic 1 , Cynthia Gendics 1<br />

1 St Luke’s-Roosevelt Hospital; Columbia University (New York, United States).<br />

Aim: The management of the chronic lower leg ulcer revolves around the TIME<br />

principals. NPWT has been used extensively in this field. Therefore, we undertook a<br />

prospective trial of an affordable low profile SU-NPWT on chronic lower extremity<br />

wounds that would usually be deemed too small or superficial for traditional NPWT.<br />

Methods: A prospective trial of 20 patients was undertaken in which chronic wound of<br />

the lower extremity were treated with SU-NPWT, with the pad being changed twice a<br />

week and the power unit weekly. Wound depth, appearance of granulation tissue,<br />

periwound skin integrity, patient comfort as well as digital photography and planimetry<br />

were carried out at each visit. Patients with VLU were treated under 4 layer wrap, while<br />

DFUs were treated with offloading shoes.<br />

Results: 80% were VLU, while 20% were DFU, with 10% being HIV+. The average<br />

wound duration was 14.2 months, the average size was 23.87 cm 2 (±17.67 cm 2 ). Over<br />

the course of the study the amount of beefy red tissue increased from 42.5% to 58.5%<br />

(p=0.47), while the average size decreased to 17.3 cm 2 (±15.54 cm 2 ) (p=0.069). 10% of<br />

wound closed entirely. Overall the wound became much more superficial, all patients<br />

tolerated the dressing well.<br />

Conclusion: The SU-NPWT appeared to make the wounds much more superficial while<br />

allowing for improved granulation beds, meeting the TIME principals of moisture balance<br />

and epithelial edge migration.<br />

FREE PAPER SESSION: LEG ULCERS I<br />

14<br />

Free Paper Session: Leg Ulcers I<br />

Topical application of haemoglobin to promote the wound healing<br />

of patients with Ulcus cruris venosum in a prospective, single<br />

blinded randomized clinical study<br />

Peter Engels 1<br />

1 EngelsConsult (Bergisch Gladbach, Germany).<br />

Aim: Hypoxia is one of the most critical factors limiting chronic wound healing. Therefore<br />

the improvement of wound oxygenation is getting increasing attention in modern wound<br />

care. Aim of a complementary application of haemoglobin to wounds is to improve and<br />

accelerate wound healing by providing additional oxygen through facilitated diffu-sion to<br />

hypoxic tissue.<br />

Methods: A solution comprising purified haemoglobin was added to the standard wound<br />

care procedure of patients with Ulcus cruris venosum and compared to a second group<br />

without addition of the haemoglobin. Patients were hospitalized two weeks prior to study<br />

initiation. Only pa-tients, who were refractory to the initial treatment in the hospital, were<br />

selected. In each group, 36 patients were included. Duration of treatment was 13 weeks.<br />

Primary end point was reduction of wound size or wound closing during treatment<br />

period.<br />

Results: In the group treated with the additional haemoglobin solution, an average of<br />

53% of wound size reduction was obtained (p

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