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POSTER: DRESSINGS<br />

Poster: Dressings<br />

P 284<br />

A OZONE PRODUCER OIL IN THE TREATMENT OF RECALCITRANT<br />

CHRONIC WOUNDS<br />

AnnaMaria Ippolito 1 , Paolo Cuffaro 1 , Alessandro Corsi 1 , Ornella Forma 2 ,<br />

Roberto Cassino 1<br />

1 Vulnera – Italian Vulnological Center (Turin, Italy);<br />

2 San Raffaele Hospital (Milan, Italy).<br />

Aim: The most of recalcitrant chronic wounds needs a better “breathing” and this means<br />

that we have to give more oxygen to these wounds. The wound bed preparation target is<br />

to transform a chronic wound into an acute one, which is a wounds that is going to heal:<br />

every wound needs oxygen to heal. Aim of the work is to demonstrate the effectiveness<br />

of a hyperoxydated oils gel in the management of recalcitrant wounds, especially in<br />

terms of promoting granulation, improving WBP score, avoiding colonization and to<br />

prove its “easy to use” property.<br />

Methods: The product we are testing is a hyperoxydated oils gel with filmogenic and<br />

protective function, also from the thermal point of view; it accelerates re-epithelialization<br />

promoting the proliferation of fibroblasts, as well as the secretion of cytokines and<br />

growth factors with consequent endogenous angiogenesis. Due to the strong oxidizing<br />

properties, it helps to control microbial growth. The study involves 50 patients with<br />

recalcitrant chronic ulcers of known aetiology, without signs of critical colonization and<br />

WBP score A and/or B with any amount of exudate. All patients must have 0.7 as<br />

minimum Ankle-Brachial Index; terminal and/or cancer patients and/or in<br />

immunosuppressive therapy have been (and will be) excluded. The dressing consists of<br />

applying an omogeneous layer of gel on the lesion, after cleansing with a chloroxidating<br />

solution (hypochlorite 0.05%); moist gauzes as secondary dressing. The renewal of the<br />

dressing was provided every 48 hours. The effectiveness demonstration provides the<br />

evaluation of WBP score changes and the area reduction after an observation period of<br />

4 weeks.<br />

Results: We have observed a mean area reduction of about 54% in all the patients;<br />

WBP score improved in more than 90% of patients with score B; pain reduction was<br />

reported by every patients involved with a mean decreasing of about 58%: in 7 patients<br />

the pain disappeared and more than 50% reduced the use of analgesic drugs.<br />

Conclusions: The dressing showed real effectiveness, promoting granulation and<br />

accelerating epithelialisation within a very few time; no patient had allergy/intolerance<br />

and all of them reported a decreasing of pain, until the complete relief.<br />

AM.Ippolito, P.Cuffaro, A.Corsi, O.Forma, R.Cassino<br />

P 285<br />

Evaluation of a super absorbent Pro-ionic copolymer gel<br />

Poster: Dressings<br />

Sylvie Hampton 1 , Tadej Martin 1 , Bree-Aslan Cathie 1<br />

1 Eastbourne Wound Healing Centres (Eastbourne, United Kingdom).<br />

Aim: To evaluate the performance of the Pro-ionic Copolymer Gel (PiCG) dressing in<br />

moisture management, wound bed preparation and wound bed granulation in 10 patients with<br />

chronic wounds divided over 2 cohorts<br />

Methods:<br />

• Subjects were treated over 6 or 7 visits for up to 4 weeks using the PiCG dressing<br />

• 1st cohort (5 patients) were treated using the PiCG as a primary dressing only<br />

• 2nd cohort (5 patients) were treated using the PiCG initially as a primary dressing until<br />

debridement was achieved, then the PiCG was used as the secondary dressing<br />

• All subjects were seen within the Eastbourne Wound Healing Centre (EWHC)<br />

• Photographs were obtained on each visit<br />

• pH was tested on each visit<br />

• Lined buckets of tap water were used for leg cleansing<br />

• Qualitative and quantitative data and wound progress was recorded in CRFs<br />

• Wound measurements were obtained with Digital Planimetry<br />

• Protease levels were recorded in some instances, as feasible<br />

• All subjects had ultrasound doppler assessment to measure Ankle Brachial Pressure<br />

Indices (ABPI) prior to treatment<br />

• Subjects had a range of wounds including diabetic foot ulcer, venous and arterial leg<br />

ulceration<br />

Results:<br />

• Wound size increased in 80% of the subjects in the 1st cohort; this was due to poor<br />

dressing application techniques which was addressed for the 2nd cohort<br />

• 100% of subjects in the 2nd cohort had a decrease in wound size<br />

• Equally, pain levels in cohort 1 were found to increase whereas 80% of subjects within<br />

cohort 2 had a decrease in pain levels; 1 subject (cohort 2) had an increase in pain levels<br />

• Cohort 2 used PiCG as a primary dressing in the initial stages to facilitate wound bed<br />

preparation; during this period, 80% saw no change in the size of the wound bed whilst<br />

20% saw a slight increase in the size of the wound<br />

• Debridement of the wound was achieved within 2 weeks using the PiCG<br />

• Clinicians found it easy to apply and remove each clinician stated they would wish to use<br />

the product in future treatment regimes<br />

• The PiCG dressing was found to be effective both as a primary dressing but also as a<br />

secondary dressing, aiding absorbency<br />

• The PiCG provided a degree of offloading in the diabetic foot ulcers and appeared to<br />

reduce shear and friction<br />

• The dressing remained intact in all instances with no incidence of desiccation and no need<br />

for irrigation of the wound following removal<br />

Conclusions: This evaluation demonstrated the multi-usage of a PiCG dressing across a<br />

range of chronic wounds coupled with ease of application and removal<br />

<strong>EWMA</strong> <strong>2013</strong><br />

COPENHAGEN<br />

15-17 May · <strong>2013</strong><br />

Danish Wound<br />

Healing Society<br />

171

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