Here - EWMA 2013

ORAL PRESENTATIONS
172
Free Paper Session: Negative Pressure Wound Therapy
NEGATIVE PRESSURE WOUND THERAPY WITH INSTILLATION (NPWTi) BETTER
REDUCES POST DEBRIDEMENT BIOBURDEN IN CHRONICALLY INFECTED
LOWER EXTREMITY WOUNDS THAN NPWT ALONE
John Lantis 1 , Cynthia Gendics 1 , Jamie Schwartz 1 , Ema Avdagic 1
1 St Luke’s-Roosevelt Hospital; Columbia University (New York, United States).
Aim: Overabundance of bacteria in the chronic wound plays a significant role in the
decreased ability to primarily close these wounds. We undertook a prospective study to
assess the efficacy two methods of aggressive wound bed preparation. algorithm versus
one employing sharp surgical debridement and NPWTi.
Methods: 16 patients with greater than 105 bacteria in their lower leg and foot wounds
were taken to the OR and debrided and randomized to receive one week of NPWT or
NPWTi (with.25% Dakins solution at 10 min dwell, 60 min vacuum at negative 125
mmHg). Quantitative cultures were taken at day 0,4, and 7.
Results: The NPWTi vs NPWT post debridement wound sizes were 84.25 cm 2 (±89.26
cm 2 ) vs 17.29 cm 2 (5.03 cm 2 ),after debridement there were 3 (±1) types of bacteria in
each wound, and of those bacteria there were 3.7x106 (±4x106) colony forming units
(CFUs) vs 1.8x106(±2.36x106). At one week the bacterial counts were 2 (±1) types of
bacteria per wound (p=0.17), and 2.6 x105 (±3x105) vs 2.79x106 (3.18x106) (p