Here - EWMA 2013

POSTER: ACUTE WOUNDS
Poster: Acute Wounds
P 204
A NEW TREATMENT IN THE SKIN LESIONS DUE TO RADIATION THERAPY
AnnaMaria Ippolito 1 , Ornella Forma 2 , Alessandro Corsi 1 , Paolo Cuffaro 1 ,
Roberto Cassino 1
1 Vulnera – Italian Vulnological Center (Turin, Italy);
2 San Raffaele Hospital (Milan, Italy).
Aim: The most common side effects of oncologic radiotherapy are rash or redness,
permanent pigmentation, and scarring in the treated area (radiodermatitis). Radiation
therapy causes inflammation of tissues and organs in and around the body site radiated:
for example, radiation can inflame skin to cause a burn. Aim of the work is to
demonstrate the effectiveness of a new product containing glycerosomas carrying
hyaluronate whose mechanism of action is to decrease local inflammation, to form
protective barrier and to regenerate skin.
Methods: The study involved 20 patients with skin damages due to oncologic radiation
therapy. The treatment protocol provides local treatment consisting of applying a small
amount of the product on the radiodermatitis, after cleansing with neutral wet wipes; no
secondary dressing needed. The renewal of the dressing was provided every 24 hours.
The effectiveness evaluation was based on the removal of clinical signs of inflammation
and the reduction of pain, evaluated with VAS (Visual Analogue Scale).
Results: We had pain reduction in more than 70% of patients and effectiveness in terms
of improvement of the skin condition in 100% of cases. The mean time of treatment was
about 2 months, but the pain reduction has been achieved within 3 weeks.
Conclusions: The treatment of radiodermatitis has always been quite empirical:
clinicians suggest to most of patients a nonspecific treatment with steroidal creams or
burns product. Now we think to have a specific product that can become part of an
effective protocol to prevent and care the skin damages of radiotherapy.
P 205
Poster: Acute Wounds
TREATMENT OF GRADE II AND III RADIODERMATITIS IN CANCER PATIENTS
UNDERGOING RADIOTHERAPY HEAD AND NECK
Roselie Corcini Pinto 1 , Bianca BortoliI Souza 1 , Karina Zanella Arrosi 1 ,
Fabiane Mendonça da Rosa 1 , Elaine Cristina Costa 1 , Leila Maria de Abreu Jaggi 1 ,
Neiro Waechter da Motta 1
1 Serviço de Radioterapia/Hospital Santa Rita da Irmandade Santa Casa de Misericórdia
de Porto Alegre (Porto Alegre, Brazil).
Introduction: Radiotherapy uses radioisotopes for cancer treatment leading the
malignant cells to lose their clonogenicity through the deleterious effects of radioactivity
on the tissues. In this process, the lining epithelial cells, are hit or radiodermatitis
triggering skin lesions that are decisive for the therapeutic outcome. In the literature,
there is no evidence of a protocol on the effectiveness of the products listed for the
recovery of radiodermatitis. Being at the discretion of the caregivers stopping treatment,
analgesics and anti-inflammatory, healing frequency, use of salt solutions, antibiotics and
sprays sulfadiazinas among others.
Objective: To evaluate the efficacy of antimicrobial hydrofiber overburden of comprised
of sodium carboxymethyl cellulose and ionic silver for treating radiodermatitis with
grades II and III, in respect to the time of healing, pain relief and manipulation.
Methods: A prospective cohort pilot prognosis of 20 patients with grades II and III
radiodermatitis using the cover of carboxymethylcellulose and silver. Patients were
monitored, guided and evaluated by nurses as the application of visual scale of pain,
vital signs, number of dressings made and appearance of the lesion.
Results/Conclusions: 20 of the analyzed patients, we had, pain relief in 98% in the first
24 hours and 2% in 48 hours, 100% used analgesics in the first 24 hours and 3% in 48
hours, 85% heal an exchange of dressings, and 15% had 2, 55% healed in 6 days, 35%
(5) 5% (9) and 5% (10). Thus we conclude that there was a positive response to
treatment with significant reduction of pain, reduction of injuries in an average of eight
days, and a reduction in the number of interventions without compromising the safety of
the treatment. They also emphasized the importance of the intervention of the nurse,
education and therapeutic decisions in these patients, opening a precedent for a
randomized clinical trial that is already in underway.
EWMA 2013
COPENHAGEN
15-17 May · 2013
Danish Wound
Healing Society
131