Here - EWMA 2013

FREE PAPER SESSION: NEGATIVE PRESSURE WOUND THERAPY
Free Paper Session: Negative Pressure Wound Therapy
166
IN VITRO EVALUATION OF THE FLUID DISTRIBUTION IN DIFFERENT WOUND
DRESSINGS DURING NEGATIVE PRESSURE WOUND THERAPY (NPWT)
Cornelia Wiegand 1 , Steffen Springer 1 , Martin Abel 2 , Peter Ruth 2 , Uta-Christina Hipler 1
1 Department of Dermatology, University Medical Center Jena (Jena, Germany);
2 Lohmann & Rauscher GmbH & Co. KG (Rengsdorf, Germany).
Aim: NPWT is clinically effective in treatment of chronic wounds. Studies suggest that
positive effects result from cell recruitments to the wound, where they contribute to
tissue formation. We showed that dressings used for NPWT exhibit different effects on
cells, they especially grow into large-pored foams, and on wound surface and
surrounding tissue. Here, we look at the differences in fluid distribution during NPWT
using large-pored PU-foam dressing*, drainage foil + and specialised NPT-dressing
system # .
Methods: Dressings were placed on the tissue and connected to a vacuum pump.
Experiments were carried out at -120mmHg for 8h. Dispersal of the fluid under the
dressings was tracked by IR imaging. For this, liquid was cooled to 4°C in the supply
while ambient temperature was 22°C.
Results: Dressings tested exhibited a quick fluid distribution after 60min with slopes
from 0.97 to 1.31. Steady states were reached after 160min under PU-foam* and
drainage foil + and after 180 min under NPT-dressing system # . Only for the PU-foam*
and the drainage foil + a complete and uniform fluid spread was observed, while
underneath the NPT-dressing system # a fluid distribution of no more than 70% was
achieved.
Conclusions: NPWT produces heterogeneous pressures at the wound ground, leading
to gradients that control drainage of interstitial fluid. Thus, it is of interest to investigate
the fluid distribution in dressings during NPWT. In this study, using a tissue model, it was
shown that fluid distribution during NPWT differs among dressings.
*Suprasorb ® CNPfoam/Lohmann&Rauscher, + Suprasorb ® CNPdrainagefoil/Lohmann&Rauscher, # KCI ABThera
System/KCI
167
Free Paper Session: Negative Pressure Wound Therapy
CLINICAL AND ECONOMIC EFFECTIVENESS OF THE NEGATIVE PRESSURE
WOUND THERAPY IN ACUTE AND CHRONIC WOUNDS TREATMENT
Vladimir Obolenskiy 1 , Alexander Ermolov 2 , Dmitriy Sychev 1 , Grigoriy Rodoman 2
1 City Hospital # 13 (Moscow, Russia);
2 RNRMU (Moscow, Russia).
Aim: To evaluate the effectiveness of the negative pressure wound therapy (NPWT) in
acute and chronic wounds treatment.
Methods: Treatment results comparative analysis for groups of similar age and
character pathology patients was made: open fractures of the extremities bones (OFEB),
soft tissues acute purulent diseases (STAPD), venous trophic ulcers (VTU). In the
research groups of (OFEB 68 patients; STAPD 17; VTU 9) the NPWT was used, in the
reference groups of (OFEB 64; STAPD 14; VTU 12) the traditional topical methods were
used.
Results: 1) OFEB. In the reference group the average duration of inpatient treatment
was 34.6+2.4 days, the average treatment cost per one patient was EUR 2227 and the
rate of wound complications was 14.1%. In the study group: 26.5+1.4, EUR 1888 and
0%. 2) STAPD. In the reference group the average duration of inpatient treatment was
21.6+1.9 days, wound contraction occurred in 21.4% of patients on days 18.6+0.6 and
the average treatment cost per one patient was EUR 1822. In the study group: 16.0+1.7,
100% of patients on days 10.2+1.1, EUR 1594. 3) VTU. In the reference group the
average duration of inpatient treatment was 22.8+3.8 days, ulcer healing was, on
average, 20%; and the average treatment cost per one patient was EUR 1730. In the
study group: 14.4+1.9, 100% and EUR 1282.
Conclusion: The NPWT is a clinically effective and economically efficient method.
EWMA 2013
COPENHAGEN
15-17 May · 2013
Danish Wound
Healing Society
103