Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
E-POSTER PRESENTATIONS<br />
EP 472<br />
E-Poster: Dressings<br />
USE OF A NEW HYDRO-DESLOUGHING DRESSING IN EXUDING & SLOUGHY<br />
WOUNDS<br />
Claire Marchand 1 , Natalie Smith 2 , C Bouvier 2<br />
1 Laboratoires Urgo (Chenove, France);<br />
2 Urgo Medical (Shepshed, France).<br />
Aim: Slough is usually moist, soft and often stringy in consistency, it is usually yellow,<br />
white or grey in colour and must be removed so that granulation can occur. A new hydrodesloughing<br />
dressing is now available to manage sloughy and moderately exuding<br />
wounds.<br />
Methods: 60 patients gave their consent to be evaluated over 15 sites. Wounds<br />
acceptable for inclusion were chronic exuding wounds in the desloughing phase, acute<br />
wounds, cancerous wounds and lesions without any clinical signs of infection. The<br />
evaluation was over a six week period – wound surface area precentage of sloughy and<br />
granulation tissue were measured and recorded on a weekly basis.<br />
Results: 60 case studies were included in analysis of wound surface area reduction<br />
– mean average reduction was 39.24% after six weeks. Overall average reduction in<br />
slough of 67% after six weeks was also recorded.<br />
Conclusion: Failure to eliminate slough will result in non-healing of a wound so correct<br />
management of the wound bed is essential. The results of this study demonstrate<br />
efficacy of this new dressing in the treatment of exuding & sloughy wounds. This is<br />
combined with excellent tolerance by patients & acceptability by both clinicians &<br />
patients.<br />
E-POSTER: DRESSINGS<br />
EP 473<br />
E-Poster: Dressings<br />
A new anti-biofilm dressing: Demonstration of enhanced silver<br />
penetration and biofilm removal in vitro<br />
David Parsons 1 , Darryl Short 1 , Victoria Rowlands 1 , Nayer Sultana 1<br />
1 ConvaTec Global Development Centre (Deeside, United Kingdom).<br />
Aim: To evaluate the effectiveness of a new absorbent enhanced-antimicrobial silver<br />
dressing (EASH) in the treatment of bacterial biofilms.<br />
Methods: An in vitro method of growing standardized biofilms of Staphylococcus aureus<br />
(NCIMB 9518) on membrane-filter discs was developed. Biofilms were characterized<br />
using microbiological counting techniques, confocal laser-scanning microscopy and<br />
scanning electron microscopy. Biofilm discs were treated with prehydrated EASH, EASH<br />
without the antimicrobial components (non-EASH) or non-EASH with silver (SH). After 24<br />
hours the dressings were removed and the residual biofilm on each disc was analyzed<br />
for silver and calcium. The amount of biofilm physically removed by the dressing was<br />
semi-quantitatively assessed using a biofilm exopolymeric substance (eps) stain.<br />
Results: Reduction in calcium remaining on the filter disc correlated with the eps<br />
removed, both being approximately 50%. The amount of biofilm removed was consistent<br />
for each test dressing, irrespective of the presence of an antibacterial or antibiofilm<br />
formulation. The amount of silver in the residual biofilms treated with EASH was<br />
approximately 25% higher than for those treated with SH.<br />
Conclusion: Given that EASH and SH dressings contain an identical amount of silver<br />
and have similar silver-release kinetics; it is reasonable to conclude that the EASH<br />
formulation facilitates a more efficient and effective transfer of the antimicrobial agent to<br />
the biofilm-embedded bacteria. Biofilm removal is a mechanical effect and is a<br />
consequence of the base dressing structure.<br />
272
Change language