Boreskov Institute of Catalysis of the Siberian Branch of Russian ...

OP-III-11The CCS is also very well suited for chiral separation of amino-acid derivatives usingliquid-liquid extraction. Excellent results were obtained using a chiral cinchona alkaloidextractant 3 in a water-dichloro-ethane system.Biphasic enzymatic reactions may also be performed conveniently in the CCS. Thebiphasic Rhizomucor miehei lipase catalysed esterification of oleic acid with n-butanol to thecorresponding ester in a heptane/water mixture was shown to proceed with oleic acidconversions of up to 70%.ConclusionsWe have demonstrated the applicability of a highly integrated reactor/separator device forinteresting biphasic chemical reactions. Details about the systems including optimizationstudies (kinetic- and reactor modeling) will be reported in the presentation.References1. a) D.H. Meikrantz et al. Centrifugal separator. US patent 5,762,800. 1998. b)www.auxill.nl/uk/cinc.separators.php c). www.cincsolutions.com2. a) F. Ma & M. A. Hanna, Bioresour. Technol., 70, 1-15 (1999). b) J. M. Marchetti, V. U. Michel & A. F.Errazu, Renew. Sust. Energy Rev., 11, 1300-1311 (2007)3. Lindner, W. and Lämmerhofer, M, US Patent Eur. Pat. Appl. No. 96 109 072.7, 1996.111