section 1 - World Intellectual Property Organization

42/1998
22 Oct/oct 1998 PCT Gazette - Section I - Gazette du PCT 14723
(11) WO 98/46567
(21) PCT/US98/07872
(13) A1
(22) 16 Apr/avr 1998 (16.04.1998)
(25) en (26) en
(31) 08/834,361 (32) 16 Apr/avr 1997
(16.04.1997)
(33) US
(43) 22 Oct/oct 1998 (22.10.1998)
(51) 6 C07D 209/08
(54) • METHOD OF SYNTHESIZING ISOINDOLE-
QUINONES AND DERIVATIVES THEREOF
•
PROCEDE DE SYNTHESE D’ISO–
INDOLEQUINONES ET DERIVES COR-
RESPONDANTS
(63) US 08/834,361 (CIP)
16 Apr/avr 1997 (16.04.1997)
(71) THE UNIVERSITY OF AKRON [US/US]; 302
E. Buchtel Commons, Akron, OH 44325 (US).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) YOUNGS, Wiley, J. [US/US]; 113 Harmony
Hills Road, Akron, OH 44321 (US). CHA-
KRABORTY, Manisha [US/US]; Apartment 1,
53 S. College Street, Akron, OH 44308 (US).
(74) WEBER, Ray, L. et al. / etc.; Renner, Kenner,
Greive, Bobak, Taylor & Weber, 1610 First National
Tower, Akron, OH 44308 (US).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH HU IL
IS JP KE KG KP KR KZ LC LK LR LS LT LU
LV MD MG MK MN MW MX NO NZ PL PT RO
RU SD SE SG SI SK SL TJ TM TR TT UA UG
US UZ VN YU ZW; AP (GH GM KE LS MW SD
SZ UG ZW); EA (AM AZ BY KG KZ MD RU TJ
TM); EP (AT BE CH CY DE DK ES FI FR GB
GR IE IT LU MC NL PT SE); OA (BF BJ CF CG
CI CM GA GN ML MR NE SN TD TG).
(11) WO 98/46568 (13) A1
(21) PCT/JP98/01465
(22) 31 Mar/mar 1998 (31.03.1998)
(25) ja (26) ja
(31) 9/93723 (32) 11 Apr/avr 1997 (33) JP
(11.04.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(51) 6 C07D 211/58
(54) • PROCESS FOR PRODUCING
1–CHLOROCARBONYL–4–
PIPERIDINOPIPERIDINE OR
HYDROCHLORIDE THEREOF
• PROCEDE DE PRODUCTION
DE 1–CHLOROCARBONYL–4–
PIPERIDINOPIPERIDINE OU
D’HYDROCHLORURE DE CELLE–CI
(71) KABUSHIKI KAISHA YAKULT HONSHA
[JP/JP]; 1–19, Higashishinbashi 1–chome, Minato–ku,
Tokyo 105–8660 (JP).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) HIROTA, Hiroshi [JP/JP]; 22–2–403, Osugi
1–chome, Edogawa–ku, Tokyo 132–0022 (JP).
(74) ARUGA, Mitsuyuki et al. / etc.; Kyodo Building,
3–6, Nihonbashiningyocho 1–chome, Chuo–ku,
Tokyo 103–0013 (JP).
(81) AU BR CA CN IL KR MX US; EA (AM AZ BY
KG KZ MD RU TJ TM); EP (AT BE CH DE DK
ES FI FR GB GR IE IT LU MC NL PT SE).
(11) WO 98/46569 (13) A1
(21) PCT/JP98/01629
(22) 8 Apr/avr 1998 (08.04.1998)
(25) ja (26) ja
(31) 9/110153 (32) 11 Apr/avr 1997
(11.04.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(33) JP
(51) 6 C07D 211/60, 221/20, 401/12, 471/10, A61K
31/445, 31/495
(54) • BENZENE DERIVATIVES
• DERIVES DE BENZENE
(71) SUMITOMO PHARMACEUTICALS CO.,
LTD. [JP/JP]; 2–8, Doshomachi 2–chome,
Chuo–ku, Osaka–shi, Osaka 541–8510 (JP).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) UEKI, Yasuyuki [JP/JP]; 1–J–406, Mukogaoka
5–chome, Sanda–shi, Hyogo 669–1544 (JP).
OKAZAKI, Kazuhiko [JP/JP]; Room 416, Sumitomo
Pharmaceuticals Nishinomiya dormitory,
4–15, Maruhashi–cho, Nishinomiya–shi, Hyogo
662–0831 (JP). SEKI, Hitoshi [JP/JP]; 10–102,
Sanjouminami–machi 5–chome, Ashiya–shi,
Hyogo 659–0086 (JP). NAGAMINE, Jun [JP/JP];
Room 343, Sumitomo Chemical Sone Apartment,
10–3, Sonehigashimachi 2–chome, Toyonaka–shi,
Osaka 561–0802 (JP). KUMAGAI, Kazuo [JP/JP];
53–6, Keyaki–dai 3–chome, Sanda–shi, Hyogo
669–1321 (JP).
(74) NAKAMURA, Toshio; Legal & Patent Dept., Sumitomo
Pharmaceuticals Co., Ltd., 1–98, Kasugadenaka
3–chome, Konohana–ku, Osaka–shi, Osaka
554–0022 (JP).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH GM
GW HU ID IL IS JP KE KG KR KZ LC LK LR
LS LT LU LV MD MG MK MN MW MX NO NZ
PL PT RO RU SD SE SG SI SK SL TJ TM TR
TT UA UG US UZ VN YU ZW; AP (GH GM KE
LS MW SD SZ UG ZW); EA (AM AZ BY KG
KZ MD RU TJ TM); EP (AT BE CH CY DE DK
ES FI FR GB GR IE IT LU MC NL PT SE); OA
(BF BJ CF CG CI CM GA GN ML MR NE SN
TD TG).
(11) WO 98/46570 (13) A1
(21) PCT/US98/07744
(22) 10 Apr/avr 1998 (10.04.1998)
(25) en (26) en
(31) 60/043,624 (32) 14 Apr/avr 1997
(14.04.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(33) US
(51) 6 C07D 223/16, 241/02, 265/30, 401/00, 401/14,
403/00, 405/14, 409/14, 413/00, 417/00, 455/02,
471/02, A61K 31/44, 31/495, 31/50, 31/505,
31/535, 31/54, 31/55
(54) •
•
SUBSTITUTED HETEROAROMATIC 5–HT1F
AGONISTS
AGONISTES 5–HT1F HETEROAROMA-
TIQUES SUBSTITUES
(71) ELI LILLY AND COMPANY [US/US]; Lilly
Corporate Center, Indianapolis, IN 46285 (US).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) FILLA, Sandra, Ann [US/US]; 1680 Williamsburg
Lane, Franklin, IN 46131 (US). KRU-
SHINSKI, Joseph, Herman, Jr. [US/US]; 1633
Beckenbauer Way, Indianapolis, IN 46214 (US).
SCHAUS, John, Mehnert [US/US]; 135 Raintree
Drive, Zionsville, IN 46077 (US).
(74) TITUS, Robert, D. et al. / etc.; Eli Lilly and
Company, Lilly Corporate Center, Indianapolis, IN
46285 (US).
(81) AL AM AU AZ BA BB BG BR BY CA CN CU
CZ EE GE GH GM GW HU ID IL IS JP KE KG
KP KR KZ LC LK LR LS LT LV MD MG MK
MN MW MX NO NZ PL RO RU SD SG SI SK
SL TJ TM TR TT UA UG US UZ VN YU ZW;
AP (GH GM KE LS MW SD SZ UG ZW); EA
(AM AZ BY KG KZ MD RU TJ TM); OA (BF BJ
CF CG CI CM GA GN ML MR NE SN TD TG).
Published / Publiée : (c)
(11) WO 98/46571 (13) A1
(21) PCT/US98/07614
(22) 17 Apr/avr 1998 (17.04.1998)
(25) en (26) en
(31) 08/840,910 (32) 17 Apr/avr 1997
(17.04.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(33) US
(51) 6 C07D 233/44, 233/48, 233/46, 233/66, 401/00,
405/00, 409/00, 411/00, 413/00, 417/00, 419/00,
421/00
(54) •
•
METHODS FOR SYNTHESIZING 2–
SUBSTITUTED IMIDAZOLES
METHODES DE SYNTHESE D’IMIDAZOLES
2–SUBSTITUES
(71) SEPRACOR INC. [US/US]; 111 Locke Drive,
Marlborough, MA 01752 (US).
(72) HONG, Yaping; 3 Ward Farm Circle, Framingham,
MA 01701 (US). BAKALE, Roger, P.; 4 Comstock
Drive, Shrewsbury, MA 01545 (US). SENA-
NAYAKE, Chrisantha, H.; 11 Old Farm Circle,
Shrewsbury, MA 01545 (US).
(74) LAWRENCE, Stanton, T., III et al. / etc.; Pennie
& Edmonds LLP, 1155 Avenue of the Americas,
New York, NY 10036 (US).
(81) AU CA JP; EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE).
(11) WO 98/46572 (13) A1
(21) PCT/US98/07453
(22) 10 Apr/avr 1998 (10.04.1998)
(25) en (26) en
(31) 08/834,658 (32) 11 Apr/avr 1997
(11.04.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(51) 6 C07D 233/48, 401/06, 403/06, A61K 31/47,
31/415, 31/505
(54) •
•
(33) US
IMIDAZOLE AND IMIDAZOLINE DERIVA-
TIVES AND USES THEREOF
DERIVES D’IMIDAZOLE ET
D’IMIDAZOLINE ET LEURS UTILISATIONS
(71) SYNAPTIC PHARMACEUTICAL CORPORA-
TION [US/US]; 215 College Road, Paramus, NJ
07652 (US).
(72) WONG, Wai, C.; 34 Columbia Street, Newark,
NJ 07102 (US). JEON, Yoon, T.; 411 Ponfield
Place, Ridgewood, NJ 07450 (US). DHAR, T.,
G., Murali; 32 East Periwinkle Lane, Hichins
Farm, Newark, DE 19711 (US). GLUCHOWSKI,
Charles; 154 Coolspring Court, Danville, CA
94506 (US).
(74) WHITE, John, P.; Cooper & Dunham LLP, 1185
Avenue of the Americas, New York, NY 10036
(US).