section 1 - World Intellectual Property Organization

42/1998
14724 PCT Gazette - Section I - Gazette du PCT 22 Oct/oct 1998
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH GM
GW HU ID IL IS JP KE KG KP KR KZ LC LK
LR LS LT LU LV MD MG MK MN MW MX NO
NZ PL PT RO RU SD SE SG SI SK SL TJ TM
TR TT UA UG UZ VN YU ZW; AP (GH GM KE
LS MW SD SZ UG ZW); EA (AM AZ BY KG
KZ MD RU TJ TM); EP (AT BE CH CY DE DK
ES FI FR GB GR IE IT LU MC NL PT SE); OA
(BF BJ CF CG CI CM GA GN ML MR NE SN
TD TG).
Published / Publiée : (c)
(11) WO 98/46573 (13) A1
(21) PCT/JP98/01655
(22) 10 Apr/avr 1998 (10.04.1998)
(25) ja (26) ja
(31) 9/132742 (32) 15 Apr/avr 1997 (33) JP
(15.04.1997)
(31) 9/273226 (32) 28 Aug/août 1997 (33) JP
(28.08.1997)
(31) 9/273227 (32) 28 Aug/août 1997 (33) JP
(28.08.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(51) 6 C07D 233/90, 401/06, 403/06, 405/12, A61K
31/415, 31/535
(54) • 2–SUBSTITUTED CARBAMOYLIMIDAZO-
LECARBOXYLIC ACID DERIVATIVES AND
VASCULAR–WALL THICKENING INHI-
BITOR
• DERIVES D’ACIDE 2–SUBSTITUE CAR-
BAMOYLIMIDAZOLECARBOXYLIQUE ET
INHIBITEUR DE L’EPAISSISSEMENT DE
LA PAROI VASCULAIRE
(71) KISSEI PHARMACEUTICAL CO., LTD.
[JP/JP]; 19–48, Yoshino, Matsumoto–shi, Nagano
399–8710 (JP).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) HARADA, Hiromu [JP/JP]; 8054, Oaza
Nakagawa, Shiga–mura, Higashichikuma–gun, Nagano
399–7411 (JP). KUSAMA, Hiroshi [JP/JP];
2–8–13, Kotobukidai, Matsumoto–shi, Nagano
399–0025 (JP). NONAKA, Yoshinori [JP/JP];
Fureguransu–Hanamizuki C202, 4951–2, Oaza
Toyoshina, Toyoshina–machi, Minamiazumi–gun,
Nagano 399–8205 (JP). YAZAKI, Toshikazu
[JP/JP]; 913–4, Oaza Hario, Asahi–mura, Higashichikuma–gun,
Nagano 390–1103 (JP). FUSHIMI,
Nobuhiko [JP/JP]; 89–6, Oaza Okadashimookada,
Matsumoto–shi, Nagano 390–0313 (JP). KA-
MATA, Koji [JP/JP]; Fureguransu–Merodi A101,
4363–1, Oaza Shimauchi, Matsumoto–shi, Nagano
390–0851 (JP).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GM GW
HU ID IL IS JP KE KG KR KZ LC LK LR LS LT
LU LV MD MG MK MN MW MX NO NZ PL PT
RO RU SD SE SG SI SK TJ TM TR TT UA UG
US UZ VN; AP (GH GM KE LS MW SD SZ UG
ZW); EA (AM AZ BY KG KZ MD RU TJ TM);
EP (AT BE CH CY DE DK ES FI FR GB GR IE
IT LU MC NL PT SE); OA (BF BJ CF CG CI CM
GA GN ML MR NE SN TD TG).
(11) WO 98/46574 (13) A1
(21) PCT/EP98/02172
(22) 14 Apr/avr 1998 (14.04.1998)
(25) en (26) en
(31) 9707693.9 (32) 16 Apr/avr 1997
(16.04.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(51) 6 C07D 237/20, 237/34, A61K 31/50
(33) GB
(54) • PYRIDAZINE AND PHTHALAZINE DERI-
VATIVES, PROCESS OF THEIR PREPARA-
TION AND THEIR USE AS ANTICONVUL-
SANTS
• DERIVES DE PYRIDAZINE ET DE PHTALA-
ZINE, LEUR PROCEDE DE PREPARATION
ET LEUR UTILISATION COMME ANTI–
CONVULSIFS
(71) SMITHKLINE BEECHAM PLC [GB/GB]; New
Horizons Court, Brentford, Middlesex TW8 9EP
(GB).
(for all designated States except / pour tous les États
désignés sauf US)
(72, 75) HARLING, John, David [GB/GB]; SmithKline
Beecham Pharmaceuticals, New Frontiers
Science Park South, Third Avenue, Harlow, Essex
CM19 5AW (GB). HERDON, Hugh, Jonathan
[GB/GB]; SmithKline Beecham Pharmaceuticals,
New Frontiers Science Park South, Third Avenue,
Harlow, Essex CM19 5AW (GB). ORLEK, Barry,
Sidney [GB/GB]; SmithKline Beecham Pharmaceuticals,
New Frontiers Science Park South,
Third Avenue, Harlow, Essex CM19 5AW (GB).
THOMPSON, Mervyn [GB/GB]; SmithKline
Beecham Pharmaceuticals, New Frontiers Science
Park South, Third Avenue, Harlow, Essex CM19
5AW (GB).
(74) WEST, Vivien; SmithKline Beecham, Corporate
Intellectual Property, New Horizons Court,
Brentford, Middlesex TW8 9EP (GB).
(81) CA JP US; EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE).
Published / Publiée : (c)
(11) WO 98/46575 (13) A1
(21) PCT/US98/07644
(22) 14 Apr/avr 1998 (14.04.1998)
(25) en (26) en
(31) 60/043,327 (32) 15 Apr/avr 1997 (33) US
(15.04.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(51) 6 C07D 239/00, A01N 43/54
(54) • CRAMBESCIDIN COMPOUNDS
• COMPOSES DE CRAMBESCIDINE
(71) PHARMA MAR, S.A. [ES/ES]; Calle de la Calera,
3, Poligono Industrial de Tres Cantos, E–28760
Tres Cantos (ES). LINEK, Ernest, V. [US/US];
130 Water Street, Boston, MA 02109 (US).
(72) SHI, Jian–Gong; University of Illinois, 349 Administration
Building, 508 South Wright Street, Urbana,
IL 61801 (US). SUN, Furong; University of
Illinois, 349 Administration Building, 508 South
Wright Street, Urbana, IL 61801 (US). RINE-
HART, Kenneth, L.; 454 Roger Adams Lab, 600
South Matthew Avenue, Urbana, IL 61801–3792
(US).
(74) LINEK, Ernest, V. et al. / etc.; Dike, Bronstein,
Roberts & Cushman, LLP, 130 Water Street,
Boston, MA 02109 (US).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH GM
GW HU ID IL IS JP KE KG KP KR KZ LC LK
LR LS LT LU LV MD MG MK MN MW MX NO
NZ PL PT RO RU SD SE SG SI SK SL TJ TM
TR TT UA UG UZ VN YU ZW; AP (GH GM KE
LS MW SD SZ UG ZW); EA (AM AZ BY KG
KZ MD RU TJ TM); EP (AT BE CH CY DE DK
ES FI FR GB GR IE IT LU MC NL PT SE); OA
(BF BJ CF CG CI CM GA GN ML MR NE SN
TD TG).
Published / Publiée : (c)
(11) WO 98/46576 (13) A2
(21) PCT/US98/07092
(22) 8 Apr/avr 1998 (08.04.1998)
(25) en (26) en
(31) 08/843,369 (32) 15 Apr/avr 1997 (33) US
(15.04.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(51) 6 C07D 243/24, A61K 31/55
(54) • HALO–ALKOXYCARBONYL PRODRUGS
• PROMEDICAMENTS HALOALCOXY-
CARBONYLES
(71) GENENTECH, INC. [US/US]; 1 DNA Way,
South San Francisco, CA 94080–4990 (US).
(72) BLACKBURN, Brent; 154 Yerba Buena Avenue,
San Francisco, CA 94127 (US). OLIVERO, Alan,
G.; 680 Highland Avenue, Half Moon Bay, CA
94019 (US). ROBARGE, Kirk; 1260 Haight
Street, San Francisco, CA 94117 (US).
(74) KUBINEC, Jeffrey, S. et al. / etc.; Genentech,
Inc., 1 DNA Way, South San Francisco, CA
94080–4990 (US).
(81) AL AM AT AU AZ BA BB BG BR BY CA CH
CN CU CZ DE DK EE ES FI GB GE GH GM
GW HU ID IL IS JP KE KG KP KR KZ LC LK
LR LS LT LU LV MD MG MK MN MW MX NO
NZ PL PT RO RU SD SE SG SI SK SL TJ TM
TR TT UA UG UZ VN YU ZW; AP (GH GM KE
LS MW SD SZ UG ZW); EA (AM AZ BY KG
KZ MD RU TJ TM); EP (AT BE CH CY DE DK
ES FI FR GB GR IE IT LU MC NL PT SE); OA
(BF BJ CF CG CI CM GA GN ML MR NE SN
TD TG).
(11) WO 98/46577 (13) A1
(21) PCT/US98/07454
(22) 10 Apr/avr 1998 (10.04.1998)
(25) en (26) en
(31) 08/843,031 (32) 11 Apr/avr 1997 (33) US
(11.04.1997)
(43) 22 Oct/oct 1998 (22.10.1998)
(51) 6 C07D 263/04
(54) • NOVEL OXAZOLIDINONES AND ME-
THODS FOR THE SYNTHESIS AND USE OF
SAME
• NOUVELLES OXAZOLIDINONES ET PRO-
CEDES DE SYNTHESE ET D’UTILISATION
DE CES COMPOSES
(71) THE TRUSTEES OF THE UNIVERSITY OF
PENNSYLVANIA [US/US]; Suite 300, 3700 Market
Street, Philadelphia, PA 19104 (US).
(72) SMITH, Amos, B., III; 517 General Lafayette
Road, Merion, PA 19066 (US). HIRSCHMANN,
Ralph, F.; 740 Palmer Place, Blue Bell, PA 19422
(US). SPRENGELER, Paul, A.; 614 S. 26th
Street, Philadelphia, PA 19146 (US). BENO-
WITZ, Andrew, B.; 179 Campmeeting Road,
Willow Grove, PA 19090 (US). FAVOR, David,
A.; Apartment C–409, 310 S. Easton Road, Glenside,
PA 19038 (US).
(74) MACKIEWICZ, John, J. et al. / etc.; Woodcock
Washburn Kurtz Mackiewicz & Norris LLP, 46th
floor, One Liberty Place, Philadelphia, PA 19103
(US).
(81) CA JP; EP (AT BE CH CY DE DK ES FI FR GB
GR IE IT LU MC NL PT SE).
Published / Publiée : (c)
(11) WO 98/46578 (13) A1
(21) PCT/GB98/01076
(22) 14 Apr/avr 1998 (14.04.1998)