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Windows QTL Cartographer 2.5 - FTP Directory Listing

Windows QTL Cartographer 2.5 - FTP Directory Listing

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<strong>Windows</strong> <strong>QTL</strong> <strong>Cartographer</strong> <strong>2.5</strong><br />

This dialog is fairly self-explanatory. The Hypothesis definitions box describes the conditions for each<br />

hypothesis, with a=additive and d=dominant. The LR setting box describes pre-set likelihood ratio<br />

hypotheses.<br />

Click OK to apply the selected hypotheses options to your display.<br />

Showing <strong>QTL</strong> information<br />

Select Effects>Show <strong>QTL</strong> Information… or click on the toolbar to display the Show <strong>QTL</strong> Information<br />

dialog. From here, you can show <strong>QTL</strong>s from a simulation parameter file or show summary <strong>QTL</strong><br />

information from the likelihood ratio graph peaks.<br />

Select the Open <strong>QTL</strong> information file option and then the Browse… button to select a file that has the<br />

<strong>QTL</strong> positions and effects settings you want to use for the display.<br />

Select the Show one or two LOD interval options, as desired, to show empiric <strong>QTL</strong> confidence<br />

intervals—95 percent is one LOD and 99 percent is two LOD.<br />

Select the Automatically locate <strong>QTL</strong>s option to specify parameters Win<strong>QTL</strong>Cart will use to find <strong>QTL</strong>s<br />

in the results. Use the spin dials to specify the minimum acceptable cM range that defines a <strong>QTL</strong> peak;<br />

if the peak's distance is less than this value, then the highest peak will be considered a <strong>QTL</strong>. The<br />

minimum acceptable LOD scale as measured by the highest and lowest points of a <strong>QTL</strong> peak on the<br />

graph. Both of these requirements must be met for a peak to be considered a <strong>QTL</strong>.<br />

© 2010 N.C. State University, Bioinformatics Research Center

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