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Windows QTL Cartographer 2.5 - FTP Directory Listing

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© 2010 N.C. State University, Bioinformatics Research Center<br />

Win<strong>QTL</strong>Cart Procedures 75<br />

Token -gqtltest. (line 17) To test two sets of <strong>QTL</strong> effects (see token -str1 and -str2) have the same<br />

effects or not. The number followed by the token is the <strong>QTL</strong> effect number of each set.<br />

Token -str1 and -str2. (line 18, 19) Every three numbers (population, trait, and <strong>QTL</strong>) indicate a <strong>QTL</strong><br />

effect.<br />

For example.<br />

-gqtltest 2<br />

-str1 1 1 1 1 1 2<br />

-str2 2 1 1 2 1 2<br />

This is to test the following assumption: population 1, trait 1, <strong>QTL</strong> effect 1 equal to population 2, trait 1,<br />

<strong>QTL</strong> effect 1 as well as population 1, trait 1, <strong>QTL</strong> effect 2 equal to population 2, trait 1, <strong>QTL</strong> effect 2. or<br />

not.<br />

Token -end. (line 20) End of Mt-MIM Control File.<br />

Mt-MIM Functions<br />

In the Refine Model Group, you can select one of following functions from the pull-down menu.<br />

1. Model parameter estimation<br />

To do the parameters estimation for current model. The likelihood value is displayed in information<br />

window on the bottom and the detailed result is in the result file. You can compare the likelihood values<br />

between two <strong>QTL</strong> models (likelihood test) to do certain decision, such as the new <strong>QTL</strong> is significant or<br />

not, The two <strong>QTL</strong> is the same or not etc.<br />

2. Test all <strong>QTL</strong> effects<br />

To test the value is zero or not for each of the <strong>QTL</strong> effects (additive, dominant, and epistasis).<br />

3. Optimize <strong>QTL</strong> positions<br />

To go through whole genome (you can set the walk speed, such 1.0 cM), find best position for each<br />

<strong>QTL</strong>.<br />

4. Search main <strong>QTL</strong>(s)<br />

If you do not know the new <strong>QTL</strong>'s chromosome and position, then to assign value -1 to the<br />

chromosome string and Win<strong>QTL</strong>Cart will search the best chromosome number and position for you<br />

automatically.<br />

5. Search epistasis interaction(s)<br />

If you want to find the best <strong>QTL</strong> interaction, then assign value -1 to <strong>QTL</strong>-1 and <strong>QTL</strong>-2 and Win<strong>QTL</strong>Cart<br />

will find out the best <strong>QTL</strong> number 1 and <strong>QTL</strong> number 2 for you automatically.<br />

6. Graphic and summary result<br />

To obtain the graph result file and text summary file.<br />

7. Test Pleiotropy in current population

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