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James Stewart-Calculus_ Early Transcendentals-Cengage Learning (2015)

A five star textbook for college calculus

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230 Chapter 3 Differentiation Rules

In Section 3.4 we showed that

d

dx sbx d − b x ln b

So the rate of growth of the bacteria population at time t is

dn

dt

− d dt sn 02 t d − n 0 2 t ln 2

For example, suppose that we start with an initial population of n 0 − 100 bacteria.

Then the rate of growth after 4 hours is

dn

dt

Z − 100 ? 2 4 ln 2 − 1600 ln 2 < 1109

t−4

This means that, after 4 hours, the bacteria population is growing at a rate of about

1109 bacteria per hour. ■

ExamplE 7 When we consider the flow of blood through a blood vessel, such as a

vein or artery, we can model the shape of the blood vessel by a cylindrical tube with

radius R and length l as illustrated in Figure 8.

R

r

FIGURE 8

Blood flow in an artery

l

Because of friction at the walls of the tube, the velocity v of the blood is greatest along

the central axis of the tube and decreases as the distance r from the axis increases until

v becomes 0 at the wall. The relationship between v and r is given by the law of laminar

flow discovered by the French physician Jean-Louis-Marie Poiseuille in 1840. This

law states that

1 v − P

4l sR2 2 r 2 d

For more detailed information, see

W. Nichols and M. O’Rourke (eds.),

McDonald’s Blood Flow in Arteries:

Theoretical, Experimental, and Clinical

Principles, 5th ed. (New York, 2005).

where is the viscosity of the blood and P is the pressure difference between the ends

of the tube. If P and l are constant, then v is a function of r with domain f0, Rg.

The average rate of change of the velocity as we move from r − r 1 outward to

r − r 2 is given by

Dv

Dr − vsr 2d 2 vsr 1 d

r 2 2 r 1

and if we let Dr l 0, we obtain the velocity gradient, that is, the instantaneous rate of

change of velocity with respect to r:

Using Equation 1, we obtain

Dv

velocity gradient − lim

Dr l 0 Dr − dv

dr

dv

dr −

P

Pr

s0 2 2rd − 2

4l 2l

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