Toxicology of Industrial Compounds

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310 TOXICOLOGY OF TEXTILE CHEMICALS Figure 22.1 New developments in Germany regarding toxicology of textile chemicals. behaviour of textile chemicals to define the absolute label criteria. These uncertainties can be solved only by cooperation of the different groups and not by aggressive competition. How can we handle both developments in a proper way? At first we have to be clear about the interactions of both problem fields. Let us start with the textile chemical delivered to a finishing plant (Figures 22.2 and 22.3). Following the directives for dangerous substances or safety data sheets the product is exactly labelled and its toxicological
Figure 22.2 Possible levels to discuss the toxicology of textile chemicals. D.SEDLAK 311 properties are well described in the SDS. This is only as good as the information given to the product safety manager responsible for the possible ways of handling and processing. However, in most cases textile chemicals can be described as harmless. Nearly all show an acute oral toxicity greater than 2000 mg kg −1 although they may contain toxic substances in diluted form. Only a few of them possess an irritant character or even CMT properties. Nevertheless, many of them have impurities with these properties which are given more and more, even in low concentrations. This is a very important process
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Toxicology of Industrial Compounds
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This edition published in the Taylo
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8. Pulmonary Toxicity Studies with
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Preface A large number of chemical
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Contributors May Akrawi Department
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Beverly M.Kulig TNO Toxicology, Dep
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Richard A.Versen Schuller MTC, Heal
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1 Biomonitoring and Absorption of I
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4 BIOMONITORING AND ABSORPTION OF I
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10 BIOMONITORING AND ABSORPTION OF
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2 Toxicokinetics and Biodisposition
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14 TOXICOKINETICS AND BIODISPOSITIO
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3 Metabolic Activation of Industria
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38 METABOLIC ACTIVATION OF INDUSTRI
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4 Sizing up the Problem of Exposure
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46 SIZING UP THE PROBLEM OF EXPOSUR
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5 Metabolism of Reactive Chemicals
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62 METABOLISM OF REACTIVE CHEMICALS
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6 Methods for the Determination of
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74 METHODS FOR THE DETERMINATION OF
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PART THREE Pulmonary toxicology of
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92 CARCINOGENIC POTENTIAL OF MAN-MA
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100 CARCINOGENIC POTENTIAL OF MAN-M
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118 PULMONARY TOXICITY STUDIES WITH
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130 PULMONARY HYPERREACTIVITY TO IN
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10 Mechanisms of Pulmonary Sensitiz
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140 MECHANISMS OF PULMONARY SENSITI
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150 OCCUPATIONAL ASTHMA INDUCED BY
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12 Biomarkers and Risk Assessment K
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160 BIOMARKERS AND RISK ASSESSMENT
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168 EXTRAPOLATION OF TOXICITY DATA
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14 Molecular Approaches to Assess C
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182 MOLECULAR APPROACHES TO ASSESS
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198 EVALUATION OF TOXICITY TO THE I
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208 USE OF LONG-TERM CULTURES OF HE
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PART FIVE Mechanisms of toxicity of
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224 PEROXISOME PROLIFERATION normal
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226 PEROXISOME PROLIFERATION demons
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228 PEROXISOME PROLIFERATION Specie
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230 PEROXISOME PROLIFERATION intend
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232 PEROXISOME PROLIFERATION BENTLE
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234 PEROXISOME PROLIFERATION KRAUPP
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236 PEROXISOME PROLIFERATION POPP,
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18 Neurotoxicity Testing of Industr
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240 NEUROTOXICITY TESTING OF INDUST
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256 ENDOCRINE TOXICOLOGY OF THE THY
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258 ENDOCRINE TOXICOLOGY OF THE THY
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Page 294 and 295: 20 Testing and Evaluation for Repro
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Page 314 and 315: PART SIX Toxicity of selected class
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Page 326 and 327: 312 TOXICOLOGY OF TEXTILE CHEMICALS
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Page 370 and 371: 25 Low Dose of a Genotoxic Carcinog
Page 372 and 373: 358 CARCINOGENESIS AT LOW DOSE Tabl
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360 CARCINOGENESIS AT LOW DOSE year
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26 Controversial Mechanistic and Re
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364 CONTROVERSIAL ISSUES IN SAFETY
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374 INDEX 2-bromo-glutathionyl 64 B
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376 INDEX Gas chromatography/mass s
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378 INDEX mRNA analysis 211 Mutagen
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380 INDEX Surfactants 338-55 acute
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Toxicology of Industrial Compounds

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