Toxicology of Industrial Compounds

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52 SIZING UP THE PROBLEM OF EXPOSURE EXTRAPOLATION Table 4.2 Human unbound clearances <strong>of</strong> the compounds used in this analysis
D.BRUCE CAMPBELL 53 a Campbell DB, 1993 unpublished data. b CL=812 ml min−1
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Toxicology of Industrial Compounds
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This edition published in the Taylo
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8. Pulmonary Toxicity Studies with
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Preface A large number of chemical
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Contributors May Akrawi Department
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Beverly M.Kulig TNO Toxicology, Dep
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Richard A.Versen Schuller MTC, Heal
Page 16 and 17: 1 Biomonitoring and Absorption of I
Page 18 and 19: 4 BIOMONITORING AND ABSORPTION OF I
Page 24 and 25: 10 BIOMONITORING AND ABSORPTION OF
Page 26 and 27: 2 Toxicokinetics and Biodisposition
Page 28 and 29: 14 TOXICOKINETICS AND BIODISPOSITIO
Page 50 and 51: 3 Metabolic Activation of Industria
Page 52 and 53: 38 METABOLIC ACTIVATION OF INDUSTRI
Page 58 and 59: 4 Sizing up the Problem of Exposure
Page 60 and 61: 46 SIZING UP THE PROBLEM OF EXPOSUR
Page 74 and 75: 5 Metabolism of Reactive Chemicals
Page 76 and 77: 62 METABOLISM OF REACTIVE CHEMICALS
Page 86 and 87: 6 Methods for the Determination of
Page 88 and 89: 74 METHODS FOR THE DETERMINATION OF
Page 104 and 105: PART THREE Pulmonary toxicology of
Page 106 and 107: 92 CARCINOGENIC POTENTIAL OF MAN-MA
Page 114 and 115: 100 CARCINOGENIC POTENTIAL OF MAN-M
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102 CARCINOGENIC POTENTIAL OF MAN-M
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118 PULMONARY TOXICITY STUDIES WITH
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130 PULMONARY HYPERREACTIVITY TO IN
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10 Mechanisms of Pulmonary Sensitiz
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140 MECHANISMS OF PULMONARY SENSITI
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150 OCCUPATIONAL ASTHMA INDUCED BY
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12 Biomarkers and Risk Assessment K
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160 BIOMARKERS AND RISK ASSESSMENT
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168 EXTRAPOLATION OF TOXICITY DATA
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14 Molecular Approaches to Assess C
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182 MOLECULAR APPROACHES TO ASSESS
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198 EVALUATION OF TOXICITY TO THE I
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208 USE OF LONG-TERM CULTURES OF HE
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PART FIVE Mechanisms of toxicity of
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224 PEROXISOME PROLIFERATION normal
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226 PEROXISOME PROLIFERATION demons
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228 PEROXISOME PROLIFERATION Specie
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230 PEROXISOME PROLIFERATION intend
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232 PEROXISOME PROLIFERATION BENTLE
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234 PEROXISOME PROLIFERATION KRAUPP
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236 PEROXISOME PROLIFERATION POPP,
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18 Neurotoxicity Testing of Industr
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240 NEUROTOXICITY TESTING OF INDUST
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256 ENDOCRINE TOXICOLOGY OF THE THY
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20 Testing and Evaluation for Repro
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282 TESTING AND EVALUATION FOR REPR
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PART SIX Toxicity of selected class
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302 SPECIAL POINTS IN THE TOXICITY
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310 TOXICOLOGY OF TEXTILE CHEMICALS
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318 ANTIOXIDANTS AND LIGHT STABILIS
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340 TOXICOLOGY OF SURFACTANTS Inter
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342 TOXICOLOGY OF SURFACTANTS Figur
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344 TOXICOLOGY OF SURFACTANTS probl
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346 TOXICOLOGY OF SURFACTANTS nonio
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348 TOXICOLOGY OF SURFACTANTS and t
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350 TOXICOLOGY OF SURFACTANTS long-
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352 TOXICOLOGY OF SURFACTANTS COULS
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354
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25 Low Dose of a Genotoxic Carcinog
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358 CARCINOGENESIS AT LOW DOSE Tabl
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360 CARCINOGENESIS AT LOW DOSE year
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26 Controversial Mechanistic and Re
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364 CONTROVERSIAL ISSUES IN SAFETY
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374 INDEX 2-bromo-glutathionyl 64 B
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376 INDEX Gas chromatography/mass s
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378 INDEX mRNA analysis 211 Mutagen
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380 INDEX Surfactants 338-55 acute
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Toxicology of Industrial Compounds

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