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Toxicology of Industrial Compounds

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364 CONTROVERSIAL ISSUES IN SAFETY ASSESSMENT<br />

3.<br />

Exposure <strong>of</strong> the consumer<br />

When looking at the vast array <strong>of</strong> chemicals in use today, most <strong>of</strong> them<br />

will have industrial applications and only relatively few will directly be<br />

used by consumers. Especially highly reactive chemicals with their inherent<br />

potential for health hazards will generally not enter into consumer<br />

application fields simply due to their limited stability. But if a chemical gets<br />

to the consumer, efficient control measures can hardly be implemented, be<br />

it for the exposure per se, the exposed population, appropriate handling or<br />

prevention <strong>of</strong> misuse.<br />

4.<br />

Exposure <strong>of</strong> the general population via the environment<br />

Apart from highly reactive substances, all chemicals will to some extent<br />

enter the environment depending on their application fields and their<br />

processing to other end products. The environmental concentrations are<br />

determined by the amount released, by the distribution media, local<br />

situations and the efficacy <strong>of</strong> the different degradation processes. In<br />

general, the exposure <strong>of</strong> the population via the environment will be very<br />

low as compared to the workplace and health hazards are not to be<br />

expected. Of course highly persistent and highly toxic substances can be an<br />

exemption to this rule and should be monitored carefully.<br />

These exposure scenarios can be exemplified by a textile dyestuff:<br />

manufacturing within the chemical industry makes use <strong>of</strong> various starting<br />

materials and intermediates, which will not end up—apart from minute<br />

impurities—in the final product, and downstream exposure to these<br />

materials will be negligible. The manufacture <strong>of</strong> the dyestuff, its further<br />

handling, processing and formulation within the chemical industry can<br />

easily be controlled. But when this material is used downstream in textiledyeing<br />

workshops an efficient exposure control and appropriate handling<br />

may not always be guaranteed and higher exposures are conceivable.<br />

During the dyeing process, parts <strong>of</strong> the material enter into the<br />

environment, for example into aqueous media. This might lead to an<br />

exposure <strong>of</strong> the general population, albeit at very low concentrations.<br />

Consumer exposure can occur via migration <strong>of</strong> the dyestuff from the<br />

textile, sweat being the carrier medium or for small children the saliva, but<br />

exposure will most <strong>of</strong>ten be so low that a health hazard is not to be<br />

expected.<br />

It is one <strong>of</strong> the main concerns <strong>of</strong> industry within the processes <strong>of</strong><br />

classification and risk assessment that sufficient consideration is <strong>of</strong>ten not<br />

given to the different exposure pr<strong>of</strong>iles <strong>of</strong> each chemical. This results in<br />

simplified black and white decisions, which are not very helpful for an

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