Toxicology of Industrial Compounds

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314 TOXICOLOGY OF TEXTILE CHEMICALS Figure 22.5 Total composition of a flame retardant recipe. EEC-directive is ‘under construction’ just now which demands the finishing of all upholstery covers with flame retardant chemicals. The composition of this recipe, shown in Figure 22.4, doesn’t seem to be too complex. No special toxicological properties are apparent. The corrosive character of the phosporic acid vanishes during the application
D.SEDLAK 315 Figure 22.6 Release of chemical substances during/after a flame retardant process. by neutralizing the finished textile with alkalis. Complex reactions of the different components are expected which are supposed to form not well defined polycondensates fixed to the textile fibre. On this basis there is no apparent reason to think of any toxicological side effects. In Figure 22.5, however, you will get a good idea about the real situation. But this detailed composition should not be deceptive about the fact that this is the ‘wanted’ technical composition verified by a few analytical data. In this case about 500 actual substances can be expected. Even if we should have available all the necessary toxicological data for the components it would not help, because there is poor information about the result of the finishing process itself. This is the only reality. A first step in the right direction would be the analysis of the process offgas. The result reflects approximately the activities on the textile during
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Toxicology of Industrial Compounds
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This edition published in the Taylo
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8. Pulmonary Toxicity Studies with
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Preface A large number of chemical
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Contributors May Akrawi Department
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Beverly M.Kulig TNO Toxicology, Dep
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Richard A.Versen Schuller MTC, Heal
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1 Biomonitoring and Absorption of I
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4 BIOMONITORING AND ABSORPTION OF I
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10 BIOMONITORING AND ABSORPTION OF
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2 Toxicokinetics and Biodisposition
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14 TOXICOKINETICS AND BIODISPOSITIO
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3 Metabolic Activation of Industria
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38 METABOLIC ACTIVATION OF INDUSTRI
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4 Sizing up the Problem of Exposure
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46 SIZING UP THE PROBLEM OF EXPOSUR
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5 Metabolism of Reactive Chemicals
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62 METABOLISM OF REACTIVE CHEMICALS
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6 Methods for the Determination of
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74 METHODS FOR THE DETERMINATION OF
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PART THREE Pulmonary toxicology of
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92 CARCINOGENIC POTENTIAL OF MAN-MA
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100 CARCINOGENIC POTENTIAL OF MAN-M
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118 PULMONARY TOXICITY STUDIES WITH
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130 PULMONARY HYPERREACTIVITY TO IN
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10 Mechanisms of Pulmonary Sensitiz
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140 MECHANISMS OF PULMONARY SENSITI
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150 OCCUPATIONAL ASTHMA INDUCED BY
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12 Biomarkers and Risk Assessment K
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160 BIOMARKERS AND RISK ASSESSMENT
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168 EXTRAPOLATION OF TOXICITY DATA
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14 Molecular Approaches to Assess C
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182 MOLECULAR APPROACHES TO ASSESS
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198 EVALUATION OF TOXICITY TO THE I
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208 USE OF LONG-TERM CULTURES OF HE
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PART FIVE Mechanisms of toxicity of
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224 PEROXISOME PROLIFERATION normal
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226 PEROXISOME PROLIFERATION demons
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228 PEROXISOME PROLIFERATION Specie
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230 PEROXISOME PROLIFERATION intend
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232 PEROXISOME PROLIFERATION BENTLE
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234 PEROXISOME PROLIFERATION KRAUPP
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236 PEROXISOME PROLIFERATION POPP,
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18 Neurotoxicity Testing of Industr
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240 NEUROTOXICITY TESTING OF INDUST
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256 ENDOCRINE TOXICOLOGY OF THE THY
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Page 278 and 279: 264 ENDOCRINE TOXICOLOGY OF THE THY
Page 294 and 295: 20 Testing and Evaluation for Repro
Page 296 and 297: 282 TESTING AND EVALUATION FOR REPR
Page 314 and 315: PART SIX Toxicity of selected class
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Page 324 and 325: 310 TOXICOLOGY OF TEXTILE CHEMICALS
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Page 370 and 371: 25 Low Dose of a Genotoxic Carcinog
Page 372 and 373: 358 CARCINOGENESIS AT LOW DOSE Tabl
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Page 376 and 377: 26 Controversial Mechanistic and Re
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364 CONTROVERSIAL ISSUES IN SAFETY
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374 INDEX 2-bromo-glutathionyl 64 B
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376 INDEX Gas chromatography/mass s
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378 INDEX mRNA analysis 211 Mutagen
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380 INDEX Surfactants 338-55 acute
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Toxicology of Industrial Compounds

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