13.01.2013 Views

Dames & Moore, 1999 - USDA Forest Service

Dames & Moore, 1999 - USDA Forest Service

Dames & Moore, 1999 - USDA Forest Service

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Constituent<br />

Diesel Fuel,<br />

Light Weight<br />

Fuel Oils, and<br />

Jet Fuel<br />

Heavy fuel<br />

oils, Residual<br />

fuels, No. 6<br />

fuel oil<br />

Acute Toxicity Summary<br />

Acute inhalation can cause dizziness, headache, nausea,<br />

and fatigue in workers.<br />

Acute dermal exposure to heavy No. 6 fuel oil in rabbits<br />

caused severe dermal irritateion, weight loss, anorexia,<br />

ataxia, lethargy, toxic hepatitis, gastrointestinal irritation<br />

and congested lungs. Other grades of No. 6 fuel oil caused<br />

irritation but no systemic toxicity.<br />

TABLE 7.1-44 (CONTINUED)<br />

TOXICITY PROFILES FOR INDICATOR HAZARDOUS SUBSTANCES<br />

Chronic Toxicity Summary<br />

Chronic inhalation may induce fatigue,<br />

anxiety, mood changes and memory<br />

difficulties in workers. Animal studies<br />

indicate liver effects, reduced red blood cell<br />

count, nasal inflammatory changes, and<br />

decreased body weight gains occur after<br />

chronic inhalation exposures. Dermal<br />

exposures in mice have produced kideny<br />

lesions.<br />

Cancer Potential<br />

Tumor promotion and<br />

carcinogenesis of the middle<br />

distillates after dermal exposures<br />

is possibly due to chronic<br />

irritation and hyperplasia. IARC<br />

has classified marine diesel fuel<br />

as possibly carcinogenic to<br />

humans (Group 28) and light<br />

diesel fuels and jet fuels as Group<br />

3, not classifiable. USEPA has<br />

assigned jet fuels to Group C,<br />

possible human carcinogens. In<br />

vitro assays are generally<br />

nonpositive.<br />

Cracked bunker fuel produced<br />

skin tumors in mice after dermal<br />

application. IARC concluded<br />

there is sufficient evidence of the<br />

carcinogenicity of heavy fuel oils<br />

to classify them as Group 2B,<br />

possibly carcinogenic to humans.<br />

In vitro assays are generally<br />

nonpositive.<br />

Other<br />

Embryotoxic, fetotoxic, and<br />

teratogenic effects have not been seen.<br />

DAMES & MOORE

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!