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Dames & Moore, 1999 - USDA Forest Service

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7.0 BASELINE RISK ASSESSMENT<br />

Both a Baseline Human Health Risk Assessment (HHRA) and Baseline Ecological Risk Assessment (ERA)<br />

were prepared for the Holden Mine Site and nearby Holden Village in Chelan County. Washington (Figures<br />

7.0-1 through 7.0-3 and Table 7.0-1). The overall approach and methodology for evaluating the risks<br />

associated with the Site are discussed below.<br />

7.1 HUMAN HEALTH RISK ASSESSMENT<br />

7.1.1 Methodology<br />

The intent of the HHRA is to evaluate the potential for threats to human health based on available<br />

information collected by the USGS, USFS, Ecology, and <strong>Dames</strong> & <strong>Moore</strong>.<br />

A systematic evaluation of the potential risks to human health was conducted in accordance with guidelines<br />

outlined in the following Ecology and U.S. Environmental Protection Agency (USEPA) documents:<br />

Washington State Model Toxics Control Act-Cleanup (WAC 173-340); Model Toxics Control Act Cleanup<br />

Levels and Risk Calculations (CLARC I4 Update (Ecology, 1996); Statistical Guidance for Ecologv Site<br />

Managers (Ecology, 1992); Supplement to Statistical Guidance for Ecology Site Managers (Ecology. 1993):<br />

Risk Assessment Guidance for Superfimd, Volume I, Human Health Evaluation Manual (Part A) (USEPA.<br />

1989) and Part B (USEPA, 1991'b); W ce of Solid Waste and Emergency Response (OSWERJ Directive<br />

9285.6-03, Supplemental Guidance: Standard Default Exposure Factors (USEPA, 1 99 1 a); Guidance for<br />

Data Usability in Risk Assessment (USEPA, 1992b); and Soil Screening Guidance: Technical Background<br />

Document (USEPA, 1996).<br />

The human health risk assessment process typically involves five basic elements:<br />

1. Data Review and Evaluation. Available data were reviewed to characterize the Site and<br />

its associated constituents, define the nature and magnitude of constituent releases to<br />

environmental media (soil, air and water), and identify site-related indicator hazardous<br />

substances (IHSs).<br />

2. . Exposure Assessment. The exposure assessment defines the amount frequency, duration,<br />

and routes of receptor exposure to site-related IHSs. The exposure assessment considers<br />

both current and likely future site uses, and is based on complete exposure pathways to<br />

actual or probable receptors (i.e., the people that could come in contact with site-related<br />

IHSs). Exposure scenarios are summarized in the Exposure Pathways Model. Exposure<br />

point concentrations representative of upper-bound exposure conditions in each affected<br />

medium are also estimated in the exposure assessment. In this baseline risk assessment, the<br />

exposure assessment is conducted in the screening level human health assessment and then<br />

refined in the site-specific HHRA.<br />

3. Toxicity Assessment. The toxicity assessment serves to (I) identify the nature and degree<br />

of toxicity of each IHS, and (2) characterize the dose-response relationship (the relationship<br />

between magnitude of exposure and magnitude of adverse health effects) for each IHS.<br />

Two kinds of effects are recognized: (1) non-carcinogenic effects, and (2) carcinogenic<br />

G:\wpd.uW~\boIdm2Li\7-0.d0~ 7- 1<br />

17693-005-019Uuly 27.<strong>1999</strong>;5:16 PMDRAFT FINAL RI REPORT

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