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Dames & Moore, 1999 - USDA Forest Service

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Use of toxicity criteria (CPFs and RfDs) intentionally designed to be conservative is<br />

likely to overestimate the IHSs' toxic potency. For example, the extrapolation of animal<br />

carcinogen bioassay results to human risk at much lower levels of exposure involves a<br />

number of assumptions regarding effect threshold. interspecies extrapolation. high- to<br />

low-dose extrapolation, and route-to-route extrapolation. The scientific validity of these<br />

assumptions is uncertain; because each of the individual extrapolations are designed to<br />

prevent underestimation of risk, in concert they result in unquantifiable but potentially<br />

very significant overestimation of risk. Specifically, the extrapolation of cancer potency<br />

fiom laboratory animals to humans, which forms the basis for the cancer risk estimates,<br />

may be associated with uncertainties ranging from as much as three to five orders of<br />

magnitude (1,000 to 100,000-fold) for selected chemicals.<br />

The risk analysis does not include a likelihood evaluation. For example, it is unlikely '<br />

that the same recreational users will chronically utilize the lagoon area, Railroad Creek.<br />

Copper Creek, seeps, and portal drainage for recreational purposes. Thus. the actual risk<br />

for recreational users is likely to be significantly lower than estimated in this HHRA.<br />

In summary, because the majority of assumptions regarding representative concentrations and contact rates<br />

made in this assessment are conservative, tending to overestimate exposure and risk, the incremental risks to<br />

the defined receptor populations fiom exposure to IHSs at the site are likely to be significantly<br />

overestimated.<br />

7.1.5 Conclusions of Baseline Human Health Risk Assessment<br />

Human health risks were evaluated through a conservative screening process and a site-specific risk<br />

assessment for those constituents exceeding the screening criteria. Site-specific risk assessment results were<br />

evaluated in light of acceptable risk levels defined by MTCA (i.e., a cumulative excess cancer risk of less<br />

than 1 x 10'' and a cumulative hazard index of less than 1.0 for constituents with effects on the same target<br />

organ). Results for each media are summarized below.<br />

7.1.5.1 Surface Soil and Tailings<br />

Surface soil sample results were divided into seven areas based on exposure characteristics, population<br />

exposed, and/or physical location, as follows: 1) Holden Village, 2) vegetable garden, 3) baseball field, 4)<br />

wilderness boundary, 5) maintenance yard, 6) lagoon area, and 7) USFS guard station. Screening of<br />

constituent concentrations resulted in the elimination of the vegetable garden, baseball field, and wilderness<br />

area as areas of concern for ingestion of surface soil. In addition, the screening resulted in the elimination of<br />

the tailings piles as an area of concern for ingestion. Constituents exceeding screening criteria in the<br />

remaining four surface soil areas were selected as indicator hazardous substances (IHSs) and evaluated in<br />

the site-specific risk assessment.<br />

Cancer risks and noncancer hazard quotients for ingestion of all IHSs in all exposure areas were below the<br />

MTCA cancer risk and hazard quotient guidelines. The cancer risks ranged from 8.91 x 10.'~ for beryllium<br />

at the USFS guard station to 5.66 x 10" for arsenic in the maintenance yard. The hazard quotients ranged<br />

from 4.1 5 x 10" for beryllium at the USFS guard station soil to 2.04 x 10.' for copper in the lagoon area soil.<br />

G:\~uUW)S~utoIdrn-2\ri\74.d0~ 7-35<br />

176936OS-019Uuly 27.<strong>1999</strong>;5:16 PWRAFT FINAL IU REPORT

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