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522 W. J. Ott<br />

Velocity Measurements Across<br />

the Atrioventricular Valves<br />

Blood flow across the atrioventricular valves can easily<br />

be seen with Doppler sonography (Fig. 35.6) [14,<br />

22±26]. Blood flow velocity can be studied at the level<br />

of the mitral or tricuspid valves by placing the Doppler<br />

sample volume immediately distal to the valve<br />

leaflets in the right or left ventricle. In addition to<br />

Fig. 35.6. Gray-scale image of a color Doppler axial scan<br />

through the fetal chest at 25 weeks showing flow across<br />

the AVvalves<br />

obtaining diastolic velocities across the atrioventricular<br />

valves, the presence of valvular insufficiency can<br />

be ascertained by moving the Doppler gate retrograde<br />

through the valve opening. Valvular stenosis has been<br />

reported to be associated with increased velocity flow<br />

through the affected valve. The waveforms recorded<br />

at the level of the mitral and tricuspid valves are<br />

characterized by two diastolic peaks: an early ventricular<br />

filling peak (E wave) and a second filling peak<br />

corresponding to the active ventricular filling phase<br />

during atrial contraction (A wave; Figs. 35.7, 35.8).<br />

These waveforms can be recorded as early as 12<br />

weeks' gestational age [27].<br />

The ratio between the A and E waves (A/E) is an<br />

index of ventricular diastolic function and is related<br />

to both cardiac compliance and preload conditions.<br />

The A/E ratio shows a significant decrease with advancing<br />

gestational age but remains above unity<br />

(Figs. 35.7, 35.8). This picture is the converse of that<br />

seen in the adult and suggests that ventricular compliance<br />

is less in the fetus than the neonate but improves<br />

with advancing gestational age. Reed [23] and<br />

Reed et al. [25] have shown that in most of the fetuses<br />

studied, tricuspid flow velocities during both<br />

early and late diastole were greater than those across<br />

the mitral valve. This confirms the impression of<br />

right heart dominance in the fetus that is seen when<br />

evaluating ventricular outflow.<br />

Fig. 35.7. Doppler blood flow across the mitral (left) and tricuspid (right) valves of a 20-week fetus. Note that the A/E ratio<br />

is greater than one

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